|
RelA
|
relA
|
0.0003212 |
1 |
VF0287
|
Regulation |
(relA) Probable GTP pyrophosphokinase RelA (ATP:GTP 3'-pyrophosphotransferase) (PPGPP synthetase I) ((P)PPGPP synthetase) (GTP diphosphokinase) [RelA (VF0287) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
RpoS
|
rpoS
|
1.0028911 |
3,113 |
VF0166
|
Regulation |
(rpoS) RNA polymerase sigma factor RpoS [RpoS (VF0166) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
LigA
|
ligA
|
1.0057822 |
3,112 |
VF0165
|
Effector delivery system |
(ligA) LigA, interaptin [LigA (VF0165) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
LOS
|
galU
|
0.0009637 |
3 |
VF0044
|
Immune modulation |
(wbaP/rfbP) undecaprenyl-phosphate galactosephosphotransferase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20]
|
|
KatAB
|
katA
|
2.0028911 |
3,112 |
VF0168
|
Stress survival |
(katA) catalase/(hydro)peroxidase [KatAB (VF0168) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Capsule
|
cap8E
|
0.0003212 |
1 |
VF0003
|
Immune modulation |
(cap8E) type 8 capsular polysaccharide synthesis protein Cap8E [Capsule (VF0003) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
LPS
|
gtrB
|
0.0003212 |
1 |
VF0124
|
Immune modulation |
(gtrB) bactoprenol glucosyl transferase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301]
|
|
GspA
|
LPG_RS11000
|
0.9980726 |
3,107 |
VF0167
|
Stress survival |
(LPG_RS11000) Hsp20 family protein [GspA (VF0167) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
LPS
|
kdsA
|
1.0064247 |
3,112 |
VF0367
|
Immune modulation |
(acpXL) acyl carrier protein [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M]
|
|
SodB
|
sodB
|
0.9980726 |
3,105 |
VF0169
|
Stress survival |
(sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
FeoAB
|
feoB
|
2.0019274 |
3,113 |
VF0160
|
Nutritional/Metabolic factor |
(feoB) ferrous iron transporter B [FeoAB (VF0160) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Type IV pili
|
vfr
|
0.0019274 |
6 |
VF0082
|
Adherence |
(pilR) two-component response regulator PilR [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1]
|
|
PmiA
|
LPG_RS08655
|
1.0131706 |
3,112 |
VF0162
|
Others |
(LPG_RS08655) DUF1189 family protein [PmiA (VF0162) - Others (VFC0346)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
LPS
|
wbpE
|
0.0048185 |
15 |
VF0085
|
Immune modulation |
(wbpE) UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1]
|
|
MOMP
|
LPG_RS03055
|
4.2887889 |
3,112 |
VF0161
|
Adherence |
(omp28) major outer membrane protein [MOMP (VF0161) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Capsule
|
ugd
|
0.0003212 |
1 |
VF0560
|
Immune modulation |
(ugd) UDP-glucose 6-dehydrogenase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Enh loci
|
LPG_RS06795
|
9.4783167 |
3,113 |
VF0163
|
Others |
(LPG_RS06795) SEL1-like repeat protein [Enh loci (VF0163) - Others (VFC0346)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Type IV pili
|
pilC
|
20.9357533 |
3,113 |
VF0155
|
Adherence |
(pilF) type IV pilus biogenesis protein PilF [Type IV pili (VF0155) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Flagella
|
tsr
|
0.0003212 |
1 |
VF0430
|
Motility |
(tsr) methyl-accepting chemotaxis protein I [Flagella (VF0430) - Motility (VFC0204)] [Burkholderia pseudomallei K96243]
|
|
LPS
|
bplC
|
0.0006425 |
2 |
VF0033
|
Immune modulation |
(bplC) lipopolysaccharide biosynthesis protein [LPS (VF0033) - Immune modulation (VFC0258)] [Bordetella pertussis Tohama I]
|
|
Lsp T2SS
|
lspK
|
11.0459364 |
3,113 |
VF0154
|
Effector delivery system |
(lspL) general secretion pathway protein L [Lsp T2SS (VF0154) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Polar flagella
|
flmH
|
0.0003212 |
1 |
VF0473
|
Motility |
(flmH) short chain dehydrogenase/reductase family oxidoreductase [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119]
|
|
Flagella
|
motC
|
46.1708962 |
3,113 |
VF0157
|
Motility |
(flgK) flagellar hook-associated protein 1 FlgK [Flagella (VF0157) - Motility (VFC0204)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
MgtC
|
mgtC
|
0.0003212 |
1 |
VF1365
|
Nutritional/Metabolic factor |
(mgtC) Salmonella virulence protein MgtC [MgtC (VF1365) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Capsule
|
ctrD
|
0.0003212 |
1 |
VF0079
|
Immune modulation |
(ctrD) capsule polysaccharide export ATP-binding protein CtrD [Capsule (VF0079) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
Dot/Icm
|
dotV
|
28.0340508 |
3,113 |
VF0156
|
Effector delivery system |
(dotA) Dot/Icm type IV secretion system protein DotA [Dot/Icm (VF0156) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Hsp60
|
htpB
|
1.0009637 |
3,113 |
VF0159
|
Adherence |
(htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Flagella
|
pseB
|
0.0986187 |
303 |
VF0114
|
Motility |
(pseB) UDP-GlcNAc-specific C4,6 dehydratase/C5 epimerase [Flagella (VF0114) - Motility (VFC0204)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
Dot/Icm T4SS secreted effectors
|
lem4/smdA
|
269.6074526 |
3,113 |
VF0798
|
Effector delivery system |
(lem12) Dot/Icm type IV secretion system effector Lem12 [Dot/Icm T4SS secreted effectors (VF0798) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Purine biosynthesis
|
purCD
|
0.9832959 |
2,992 |
VF0559
|
Nutritional/Metabolic factor |
(purCD) fusion protein PurC/PurD [Purine biosynthesis (VF0559) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Pyrimidine biosynthesis
|
carB
|
0.0012849 |
4 |
VF0558
|
Nutritional/Metabolic factor |
(carB) carbamoyl phosphate synthase large subunit [Pyrimidine biosynthesis (VF0558) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
TTSS
|
escV
|
0.0003212 |
1 |
VF0191
|
Effector delivery system |
(escV) Type III secretion system major export apparatus protein [TTSS (VF0191) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
ClpC
|
clpC
|
0.0003212 |
1 |
VF0072
|
Stress survival |
(clpC) endopeptidase Clp ATP-binding chain C [ClpC (VF0072) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
ClpP
|
clpP
|
0.9987151 |
3,109 |
VF0074
|
Stress survival |
(clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
O-antigen
|
YE_RS15425
|
0.0006425 |
1 |
VF0392
|
Immune modulation |
(YE_RS15425) GDP-L-fucose synthase [O-antigen (VF0392) - Immune modulation (VFC0258)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Mip
|
mip
|
1.0003212 |
3,112 |
VF0153
|
Post-translational modification |
(mip) macrophage infectivity potentiator Mip [Mip (VF0153) - Post-translational modification (VFC0315)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Flagella
|
flgK
|
0.0006425 |
1 |
VF0394
|
Motility |
(flgK) flagellar hook-associated protein 1 FlgK [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Type IV pili
|
pilT2
|
0.0006425 |
2 |
VF0075
|
Adherence |
(pilT2) twitching motility protein PilT [Type IV pili (VF0075) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
|
|
LPS
|
wbtL
|
0.0122069 |
38 |
VF0542
|
Immune modulation |
(wbtL) glucose-1-phosphate thymidylyltransferase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
AhpC
|
ahpC
|
0.0009637 |
3 |
VF0306
|
Stress survival |
(ahpC) alkyl hydroperoxide reductase subunit AhpC [AhpC (VF0306) - Stress survival (VFC0282)] [Mycobacterium tuberculosis H37Rv]
|
|
AdeFGH efflux pump
|
adeG
|
0.0012849 |
3 |
VF0504
|
Biofilm |
(adeG) cation/multidrug efflux pump [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
Enterobactin
|
fepG
|
0.0016062 |
3 |
VF0228
|
Nutritional/Metabolic factor |
(fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
FdeC
|
fdeC
|
0.0003212 |
1 |
VF0506
|
Adherence |
(fdeC) adhesin FdeC [FdeC (VF0506) - Adherence (VFC0001)] [Escherichia coli O45:K1:H7 str. S88]
|
|
PDIM
|
ppsD
|
0.0009637 |
3 |
VF0309
|
Immune modulation |
(ppsD) phthiocerol synthesis polyketide synthase type I PpsD [PDIM (VF0309) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
|
|
CsrA
|
csrA
|
0.994539 |
3,093 |
VF0261
|
Regulation |
(csrA) carbon storage regulator CsrA [CsrA (VF0261) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
TTSS
|
yscQ
|
0.0003212 |
1 |
VF0140
|
Effector delivery system |
(yscQ) type III secretion system C ring protein [TTSS (VF0140) - Effector delivery system (VFC0086)] [Yersinia pestis CO92]
|
|
RelA
|
relA
|
1.0099582 |
3,112 |
VF0260
|
Regulation |
(relA) GTP diphosphokinase [RelA (VF0260) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
TTSS secreted effectors
|
espX2
|
0.0003212 |
1 |
VF1110
|
Effector delivery system |
(espX2) Type III secretion system effector EspX2 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
EF-Tu
|
tufA
|
2.4876325 |
3,106 |
VF0460
|
Adherence |
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
LetA/S
|
letA
|
2.0183103 |
3,113 |
VF0262
|
Regulation |
(letA) UvrY/SirA/GacA family response regulator transcription factor [LetA/S (VF0262) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Colibactin
|
clbF
|
0.0012849 |
4 |
VF0573
|
Exotoxin |
(clbF) colibactin biosynthesis dehydrogenase ClbF [Colibactin (VF0573) - Exotoxin (VFC0235)] [Klebsiella pneumoniae subsp. pneumoniae 1084]
|
|
T4SS secreted effectors
|
CBU_1566
|
0.0019274 |
6 |
VF0696
|
Effector delivery system |
(CBU_2076) Coxiella Dot/Icm type IVB secretion system translocated effector [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493]
|
|
VAS T6SS
|
vipB/mglB
|
0.0003212 |
1 |
VF0335
|
Effector delivery system |
(vipB/mglB) type VI secretion system tubule-forming protein VipB [VAS T6SS (VF0335) - Effector delivery system (VFC0086)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
MsrAB
|
msrA/B(pilB
|
0.0012849 |
4 |
VF0456
|
Stress survival |
(msrA/B(pilB)) trifunctional thioredoxin/methionine sulfoxide reductase A/B protein [MsrAB (VF0456) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
Yersiniabactin
|
ybtP
|
0.0003212 |
1 |
VF0136
|
Nutritional/Metabolic factor |
(ybtP) yersiniabactin ABC transporter ATP-binding/permease protein YbtP [Yersiniabactin (VF0136) - Nutritional/Metabolic factor (VFC0272)] [Yersinia pestis CO92]
|
|
T6SS
|
rhs/PAAR
|
0.0003212 |
1 |
VF0579
|
Effector delivery system |
(rhs/PAAR) Type VI secretion system protein, PAAR family [T6SS (VF0579) - Effector delivery system (VFC0086)] [Shigella sonnei Ss046]
|
|
Pht
|
phtA
|
1.0003212 |
3,113 |
VF0337
|
Nutritional/Metabolic factor |
(phtA) major facilitator family transporter, phagosomal transporter [Pht (VF0337) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
RtxA
|
rtxA
|
1.7163508 |
2,944 |
VF0259
|
Exotoxin |
(rtxA) structural toxin protein RtxA [RtxA (VF0259) - Exotoxin (VFC0235)] [Legionella pneumophila str. Paris]
|
|
FrgA
|
frgA
|
1.004176 |
3,111 |
VF0290
|
Nutritional/Metabolic factor |
(frgA) siderophore biosynthetic protein, iron repressed gene FrgA [FrgA (VF0290) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Alginate
|
mucP
|
0.0003212 |
1 |
VF0091
|
Biofilm |
(mucP) metalloprotease protease [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
CcmC
|
ccmE
|
6.0038548 |
3,113 |
VF0292
|
Nutritional/Metabolic factor |
(ccmC) cytochrome c-type biogenesis protein CcmC, putative heme lyase for CcmE [CcmC (VF0292) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Pyoverdine
|
pvdD
|
0.0003212 |
1 |
VF0094
|
Nutritional/Metabolic factor |
(pvdD) pyoverdine synthetase D [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
LPS
|
hisH
|
25.5191134 |
3,112 |
VF0171
|
Immune modulation |
(LPG_RS03810) class I SAM-dependent methyltransferase [LPS (VF0171) - Immune modulation (VFC0258)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Urease
|
ureB
|
0.0003212 |
1 |
VF0050
|
Stress survival |
(ureB) urease beta subunit UreB, urea amidohydrolase [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695]
|
|
Legiobactin
|
lbtA
|
4.0308384 |
3,112 |
VF0291
|
Nutritional/Metabolic factor |
(lbtA) siderophore biosynthetic enzyme LbtA [Legiobactin (VF0291) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
SodC
|
sodC
|
0.9996788 |
3,112 |
VF0170
|
Stress survival |
(sodC) superoxide dismutase (copper-zinc) [SodC (VF0170) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
TTSS secreted effectors
|
yopT
|
0.0006425 |
1 |
VF1021
|
Effector delivery system |
(yopH) type III secretion system effector YopH, protein tyrosine phosphatase [TTSS secreted effectors (VF1021) - Effector delivery system (VFC0086)] [Yersinia pestis CO92]
|
|
IraAB
|
iraA
|
2.0186315 |
3,113 |
VF0293
|
Nutritional/Metabolic factor |
(iraB) Di/tripeptide permease [IraAB (VF0293) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|