Listeria monocytogenes

单核增生李斯特氏菌
Virulence Factors: Temporal Map
VFs in isolation sources
List
Virulence factor Related gene Frequency Genomes statistics VF ID VF function Description
TFP pilM 0.0000228 1 VF1334 Adherence (pilM) pilus assembly protein PilM [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU]
Capsule cap8J 0.0003424 14 VF0003 Immune modulation (cap8J) type 8 capsular polysaccharide synthesis protein Cap8J [Capsule (VF0003) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
LPS gtrB 0.0000456 2 VF0124 Immune modulation (gtrB) bactoprenol glucosyl transferase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301]
Hyaluronic acid capsule hasC 1.0035606 43,761 VF0244 Immune modulation (hasC) UTP--glucose-1-phosphate uridylyltransferase HasC [Hyaluronic acid capsule (VF0244) - Immune modulation (VFC0258)] [Streptococcus pyogenes M1 GAS]
CNA cna 0.0000228 1 VF0005 Adherence (cna) collagen adhesin precursor [CNA (VF0005) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
Clumping factor clfA 0.0000228 1 VF0004 Adherence (clfA) Clumping factor A, fibrinogen-binding protein [Clumping factor (VF0004) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
LPS acpXL 1.0000456 43,802 VF0367 Immune modulation (acpXL) acyl carrier protein [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M]
PavB pavB/pfbB 0.0000685 3 VF0524 Adherence (pavB/pfbB) cell wall surface anchor family protein, Plasminogen- and Fibronectin-binding protein B [PavB (VF0524) - Adherence (VFC0001)] [Streptococcus pneumoniae R6]
Type VII secretion system essC 0.0011869 46 VF0403 Effector delivery system (esxD) type VII secretion system secreted protein EsxD [Type VII secretion system (VF0403) - Effector delivery system (VFC0086)] [Staphylococcus aureus subsp. aureus MW2]
Delta-hemolysin hld 0.0000228 1 VF0007 Exotoxin (hld) delta-hemolysin [Delta-hemolysin (VF0007) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
ECP yagX/ecpC 0.0000456 2 VF0404 Adherence (yagX/ecpC) E. coli common pilus usher EcpC [ECP (VF0404) - Adherence (VFC0001)] [Escherichia coli O157:H7 str. EDL933]
Porin porA 0.0000228 1 VF0081 Invasion (porA) porin PorA [Porin (VF0081) - Invasion (VFC0083)] [Neisseria meningitidis MC58]
TTSS exsE 0.0000228 1 VF0083 Effector delivery system (exsE) type III secretion system regulatory protein ExsE [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
Type IV pili fimV 0.0000456 2 VF0082 Adherence (chpA) still frameshift probable component of chemotactic signal transduction system [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1]
Fsr fsrA 0.0000456 1 VF0360 Biofilm (fsrA) response regulator [Fsr (VF0360) - Biofilm (VFC0271)] [Enterococcus faecalis V583]
LPS wzz 0.0000228 1 VF0085 Immune modulation (wzz) O-antigen chain length regulator [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1]
Xcp secretion system xcpQ 0.0000228 1 VF0084 Effector delivery system (xcpQ) general secretion pathway protein D [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
T6SS vasK/icmF 0.0000228 1 VF0480 Effector delivery system (vasK/icmF) Type VI secretion system protein [T6SS (VF0480) - Effector delivery system (VFC0086)] [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
BopD bopD 0.0002282 9 VF0362 Biofilm (bopD) sugar-binding transcriptional regulator, LacI family [BopD (VF0362) - Biofilm (VFC0271)] [Enterococcus faecalis V583]
Capsule cpsD 1.0022596 43,796 VF0361 Immune modulation (cpsB/cdsA) phosphatidate cytidylyltransferase [Capsule (VF0361) - Immune modulation (VFC0258)] [Enterococcus faecalis V583]
PhoPQ phoQ 0.0000228 1 VF0111 Regulation (phoQ) sensor protein PhoQ [PhoPQ (VF0111) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
GroEL groEL 1.0008901 43,811 VF0594 Adherence (groEL) chaperonin GroEL [GroEL (VF0594) - Adherence (VFC0001)] [Clostridium difficile 630]
SSLs set22 0.0000913 2 VF0990 Exotoxin (set19) superantigen-like protein SSL4 [SSLs (VF0990) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
Polar flagella nueA 0.0000456 2 VF0473 Motility (nueA) NeuA protein [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119]
Chu chuX 0.0000913 1 VF0234 Nutritional/Metabolic factor (chuY) ChuY [Chu (VF0234) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli O157:H7 str. EDL933]
Fur fur 0.0000456 2 VF0113 Regulation (fur) ferric iron uptake transcriptional regulator [Fur (VF0113) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
Capsule siaC/synC 0.0000456 1 VF0079 Immune modulation (siaC/synC) polysialic acid capsule biosynthesis protein SiaC [Capsule (VF0079) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
EfaA efaA 0.0000228 1 VF0354 Adherence (efaA) endocarditis specific antigen [EfaA (VF0354) - Adherence (VFC0001)] [Enterococcus faecalis V583]
OmpA ompA 0.0000228 1 VF0236 Invasion (ompA) outer membrane protein A [OmpA (VF0236) - Invasion (VFC0083)] [Escherichia coli O18:K1:H7 str. RS218]
Exe T2SS exeG 0.0000685 1 VF0478 Effector delivery system (exeF) general secretion pathway protein F [Exe T2SS (VF0478) - Effector delivery system (VFC0086)] [Aeromonas hydrophila ML09-119]
Gelatinase gelE 0.0000228 1 VF0357 Exoenzyme (gelE) coccolysin [Gelatinase (VF0357) - Exoenzyme (VFC0251)] [Enterococcus faecalis V583]
Flagella Cj0371 0.000776 27 VF0114 Motility (flaB) flagellin [Flagella (VF0114) - Motility (VFC0204)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
Cytolysin cylR2 0.0033095 144 VF0356 Exotoxin (cylR2) cytolysin regulator R2 [Cytolysin (VF0356) - Exotoxin (VFC0235)] [Enterococcus faecalis str. MMH594]
Hyaluronidase EF0818 0.0001826 7 VF0359 Exoenzyme (EF0818) polysaccharide lyase, family 8 [Hyaluronidase (VF0359) - Exoenzyme (VFC0251)] [Enterococcus faecalis V583]
Shiga toxin stxA 0.0000456 1 VF0117 Exotoxin (stxB) Shiga toxin subunit B precursor [Shiga toxin (VF0117) - Exotoxin (VFC0235)] [Shigella dysenteriae Sd197]
TTSS (SPI-1 encode) prgI 0.0000456 2 VF0116 Effector delivery system (prgI) type III secretion system needle filament protein PrgI [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
Ibes ibeC 0.0000456 2 VF0237 Invasion (ibeB) Cu(+)/Ag(+) efflux RND transporter outer membrane channel CusC [Ibes (VF0237) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
SprE sprE 0.0000228 1 VF0358 Exoenzyme (sprE) serine proteinase, V8 family [SprE (VF0358) - Exoenzyme (VFC0251)] [Enterococcus faecalis V583]
Yst1 T2SS yst1D 0.0000228 1 VF0635 Effector delivery system (yst1D) type II secretion system secretin GspD [Yst1 T2SS (VF0635) - Effector delivery system (VFC0086)] [Yersinia enterocolitica subsp. enterocolitica 8081]
InlB inlB 1.1135508 43,801 VF0070 Invasion (inlB) Internalin B [InlB (VF0070) - Invasion (VFC0083)] [Listeria monocytogenes EGD-e]
TTSS espA 0.0002511 1 VF0191 Effector delivery system (cesF) CesF, chaperone for EspF [TTSS (VF0191) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
ClpC clpC 1.002077 43,809 VF0072 Stress survival (clpC) endopeptidase Clp ATP-binding chain C [ClpC (VF0072) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
Ami ami 1.5994111 43,770 VF0071 Adherence (ami) autolysin amidase, adhesin [Ami (VF0071) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
ClpP clpP 1.0001598 43,805 VF0074 Stress survival (clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
ClpE clpE 1.0029672 43,813 VF0073 Stress survival (clpE) ATP-dependent protease [ClpE (VF0073) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
Lsp lspA 1.0007988 43,812 VF0351 Post-translational modification (lspA) signal peptidase II [Lsp (VF0351) - Post-translational modification (VFC0315)] [Listeria monocytogenes EGD-e]
Salmochelin siderophore iroB 0.0000228 1 VF0230 Nutritional/Metabolic factor (iroB) glucosyltransferase IroB [Salmochelin siderophore (VF0230) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
BSH bsh 0.9979686 43,648 VF0350 Stress survival (bsh) bile salt hydrolase [BSH (VF0350) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
Type IV pili pilT 0.0000456 2 VF0075 Adherence (pilT) twitching motility protein PilT [Type IV pili (VF0075) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
Capsule cps4B 0.0004337 18 VF0144 Immune modulation (cps4I) capsular polysaccharide biosynthesis protein Cps4I [Capsule (VF0144) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
PmrAB pmrB 0.0000228 1 VF1355 Regulation (pmrB) sensory kinase PmrB [PmrAB (VF1355) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
Hpt hpt 1.0027617 43,800 VF0264 Nutritional/Metabolic factor (hpt) hexose phosphate transport protein [Hpt (VF0264) - Nutritional/Metabolic factor (VFC0272)] [Listeria monocytogenes EGD-e]
Autolysin cbpD 0.0000456 2 VF0143 Exoenzyme (cbpD) choline binding protein D [Autolysin (VF0143) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
LPS wbtM 0.6800265 29,438 VF0542 Immune modulation (wbtM) dTDP-D-glucose 4,6-dehydratase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
TTSS secreted effectors nleG2-4 0.0001598 1 VF1111 Effector delivery system (nleG7) Type III secretion system effector NleG7, E3 Ubiquitin Ligase [TTSS secreted effectors (VF1111) - Effector delivery system (VFC0086)] [Escherichia coli O55:H7 str. CB9615]
IdeR ideR 0.0000228 1 VF0300 Regulation (ideR) Iron-dependent repressor and activator IdeR [IdeR (VF0300) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
Aureolysin aur 0.0000228 1 VF0024 Exoenzyme (aur) zinc metalloproteinase aureolysin [Aureolysin (VF0024) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
Nitrate reductase narH 0.0001141 5 VF0302 Nutritional/Metabolic factor (narG) nitrate reductase subunit alpha [Nitrate reductase (VF0302) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
AdsA adsA 0.0000228 1 VF0422 Immune modulation (adsA) Adenosine synthase A [AdsA (VF0422) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
IgA1 protease zmpC 0.0000456 2 VF0147 Immune modulation (zmpC) immunoglobulin A1 protease [IgA1 protease (VF0147) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
Capsule galE 0.0000228 1 VF0543 Immune modulation (galE) UDP-glucose 4-epimerase GalE [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
TTSS-2 secreted effectors sspH2 0.0000228 1 VF0947 Effector delivery system (sspH2) type III secretion system effector SspH2 (Salmonella secreted protein H2), novel E3 ubiquitin ligase [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
PDIM pks1 0.0000228 1 VF0309 Immune modulation (pks1) polyketide synthase [PDIM (VF0309) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
TTSS-1 secreted effectors sopE2 0.0000228 1 VF0949 Effector delivery system (sopE2) type III secretion system effector SopE2, guanine nucleotide exchange factor [TTSS-1 secreted effectors (VF0949) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
HSI-1 T6SS secreted effectors tse5/rhsP1 0.0000228 1 VF1194 Effector delivery system (tse5/rhsP1) Toxin protein Tse5 [HSI-1 T6SS secreted effectors (VF1194) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
Fap fapC 0.0000228 1 VF1191 Adherence (fapC) major amyloid subunit FapC [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1]
TTSS yopB 0.0001369 1 VF0140 Effector delivery system (lcrG) chaperone for tip protein LcrV [TTSS (VF0140) - Effector delivery system (VFC0086)] [Yersinia pestis CO92]
TTSS secreted effectors nleA/espI 0.0002282 2 VF1110 Effector delivery system (espG) Type III secretion system effector EspG, GTPase activating protein [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
RelA relA 0.0000228 1 VF0260 Regulation (relA) GTP diphosphokinase [RelA (VF0260) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
SvpA hbp2 2.0027389 43,812 VF0263 Nutritional/Metabolic factor (hbp2) hypothetical protein [SvpA (VF0263) - Nutritional/Metabolic factor (VFC0272)] [Listeria monocytogenes EGD-e]
Capsule capB 0.0000228 1 VF0141 Immune modulation (capB) CapB, involved in Poly-gamma-glutamate synthesis [Capsule (VF0141) - Immune modulation (VFC0258)] [Bacillus anthracis]
Lipase lip 0.0001598 6 VF0012 Exoenzyme (lip) triacylglycerol lipase precursor [Lipase (VF0012) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
Gamma-hemolysin hlgB 0.0000228 1 VF0011 Exotoxin (hlgB) gamma-hemolysin component B [Gamma-hemolysin (VF0011) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
Intercellular adhesion proteins icaR 0.0000685 3 VF0014 Biofilm (icaR) ica operon transcriptional regulator IcaR [Intercellular adhesion proteins (VF0014) - Biofilm (VFC0271)] [Staphylococcus aureus subsp. aureus MW2]
LLS llsD 1.7410129 12,495 VF0410 Exotoxin (llsH) ABC transporter permease protein LlsH [LLS (VF0410) - Exotoxin (VFC0235)] [Listeria innocua SLCC6294]
Shu shuA 0.0000456 2 VF0256 Nutritional/Metabolic factor (shuA) outer membrane heme/hemoglobin receptor ShuA [Shu (VF0256) - Nutritional/Metabolic factor (VFC0272)] [Shigella dysenteriae Sd197]
Isd isdA 0.0003424 13 VF0015 Nutritional/Metabolic factor (isdA) iron-regulated surface determinant protein A [Isd (VF0015) - Nutritional/Metabolic factor (VFC0272)] [Staphylococcus aureus subsp. aureus str. Newman]
SigA sigA/rpoV 0.0002511 11 VF0257 Regulation (sigA/rpoV) RNA polymerase sigma factor SigA [SigA (VF0257) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
Yersiniabactin irp1 0.0000685 2 VF0136 Nutritional/Metabolic factor (irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136) - Nutritional/Metabolic factor (VFC0272)] [Yersinia pestis CO92]
SpA spa 0.0000228 1 VF0017 Exotoxin (spa) Immunoglobulin G binding protein A precursor [SpA (VF0017) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
RTX protein frpA 0.0000228 1 VF0897 Adherence (frpA) iron-regulated protein FrpA [RTX protein (VF0897) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
SDr sdrE 0.0000685 2 VF0019 Adherence (sdrC) Ser-Asp rich fibrinogen-binding bone sialoprotein-binding protein [SDr (VF0019) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
EcbA ecbA/fss3 0.0062995 275 VF0539 Adherence (ecbA/fss3) Collagen binding MSCRAMM, EcbA/Fss3 [EcbA (VF0539) - Adherence (VFC0001)] [Enterococcus faecium DO]
Ebp pili ebpB 0.0003424 8 VF0538 Adherence (srtC) sortase [Ebp pili (VF0538) - Adherence (VFC0001)] [Enterococcus faecalis V583]
Alginate algU 0.0000456 2 VF0091 Biofilm (algU) alginate biosynthesis protein AlgZ/FimS [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
Pyoverdine pvdI 0.0000228 1 VF0094 Nutritional/Metabolic factor (pvdI) peptide synthase [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
Pyochelin pchE 0.0000228 1 VF0095 Nutritional/Metabolic factor (pchE) dihydroaeruginoic acid synthetase PchE [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
OatA oatA 1.0037204 43,811 VF0441 Immune modulation (oatA) peptidoglycan O-acetyltransferase [OatA (VF0441) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
Ent entF 0.0000228 1 VF0562 Nutritional/Metabolic factor (entF) enterobactin synthase subunit F [Ent (VF0562) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
LntA lntA 0.9979002 43,689 VF0440 Immune modulation (lntA) listeria nuclear targeted protein A [LntA (VF0440) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
LOS rffG 0.0001598 7 VF0044 Immune modulation (lpxA) UDP-N-acetylglucosamine acyltransferase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20]
LPS rfbD 0.0000228 1 VF0561 Immune modulation (rfbD) UDP-galactopyranose mutase [LPS (VF0561) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
Vip vip 0.7650241 33,452 VF0443 Invasion (vip) surface adhesin Vip [Vip (VF0443) - Invasion (VFC0083)] [Listeria monocytogenes EGD-e]
KatAB katA 0.0000228 1 VF0168 Stress survival (katA) catalase/(hydro)peroxidase [KatAB (VF0168) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
TTSS (SPI-2 encode) sseD 0.0000456 2 VF0321 Effector delivery system (ssaM) type III secretion system protein SsaM [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
Sal iroN 0.0000456 2 VF0563 Nutritional/Metabolic factor (iroN) salmochelin receptor IroN [Sal (VF0563) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
PgdA pdgA 1.0016205 43,805 VF0442 Immune modulation (pdgA) Peptidoglycan N-deacetylase [PgdA (VF0442) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
Tbp tbpA 0.0000228 1 VF0046 Nutritional/Metabolic factor (tbpA) transferrin-binding protein A [Tbp (VF0046) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
InlJ inlJ 1.0528382 43,601 VF0445 Adherence (inlJ) internalin J [InlJ (VF0445) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
Type I fimbriae fimD 0.0000456 2 VF0566 Adherence (fimC) periplasmic chaperone [Type I fimbriae (VF0566) - Adherence (VFC0001)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
ToxB toxB 0.0000913 2 VF0203 Effector delivery system (toxB) cytotoxin [ToxB (VF0203) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
Lap lap 1.0056604 43,812 VF0444 Adherence (lap) Listeria adhesion protein Lap [Lap (VF0444) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
Capsule kpsD 0.0001369 4 VF0323 Immune modulation (kpsD) capsule polysaccharide ABC transporter substrate-binding protein [Capsule (VF0323) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
SodB sodB 0.0000685 3 VF0169 Stress survival (sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
Intimin eae 0.0000228 1 VF0202 Effector delivery system (eae) intimin type gamma [Intimin (VF0202) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
Aerobactin iucB 0.0000228 1 VF0565 Nutritional/Metabolic factor (iucB) N-acetyltransferase IucB [Aerobactin (VF0565) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
LOS Cj1136 0.0001141 5 VF0326 Immune modulation (waaC) heptosyltransferase I [LOS (VF0326) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
AcrAB acrA 0.0001826 6 VF0568 Antimicrobial activity/Competitive advantage (acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
InlF inlF 0.930637 39,227 VF0447 Adherence (inlF) internalin F [InlF (VF0447) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
LapB lapB 0.9783169 42,306 VF0446 Adherence (lapB) Listeria adhesion protein LapB [LapB (VF0446) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
Curli fibers cgsE 0.0000685 1 VF1138 Adherence (cgsE) curli production assembly/transport protein CsgE [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131]
PrsA2 prsA2 1.5185219 43,811 VF0449 Post-translational modification (prsA2) post translocation chaperone PrsA2 [PrsA2 (VF0449) - Post-translational modification (VFC0315)] [Listeria monocytogenes EGD-e]
MOMP porA 0.0000228 1 VF0328 Adherence (porA) major outer membrane protein [MOMP (VF0328) - Adherence (VFC0001)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
Hemolysin hlyA 0.0002282 3 VF0207 Exotoxin (hlyA) Hemolysin A [Hemolysin (VF0207) - Exotoxin (VFC0235)] [Escherichia coli O157:H7 str. EDL933]
Stx stx2B 0.0000456 1 VF0206 Exotoxin (stx2B) shiga-like toxin II B subunit encoded by bacteriophage BP-933W [Stx (VF0206) - Exotoxin (VFC0235)] [Escherichia coli O157:H7 str. EDL933]
StcE stcE 0.0000456 2 VF0209 Exoenzyme (stcE) metalloprotease [StcE (VF0209) - Exoenzyme (VFC0251)] [Escherichia coli O157:H7 str. EDL933]
EspP espP 0.0000228 1 VF0208 Effector delivery system (espP) autotransporter, serine protease [EspP (VF0208) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
GtcA gtcA 1.0004793 43,777 VF0607 Post-translational modification (gtcA) wall teichoic acid glycosylation protein GtcA [GtcA (VF0607) - Post-translational modification (VFC0315)] [Listeria monocytogenes EGD-e]
Hyaluronidase hylB 0.0000228 1 VF0281 Exoenzyme (hylB) hyaluronidase [Hyaluronidase (VF0281) - Exoenzyme (VFC0251)] [Streptococcus agalactiae NEM316]
FeoAB feoB 0.0000228 1 VF0160 Nutritional/Metabolic factor (feoB) ferrous iron transporter B [FeoAB (VF0160) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
Capsule wcaJ 1.0039942 43,811 VF0560 Immune modulation (KP1_RS29180) acyltransferase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
MisL misL 0.0000228 1 VF0397 Adherence (misL) putative autotransporter [MisL (VF0397) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
Flagella flgC 0.0000228 1 VF0430 Motility (flgC) flagellar basal body rod protein FlgC [Flagella (VF0430) - Motility (VFC0204)] [Burkholderia pseudomallei K96243]
FupA feoB 0.0000685 3 VF0550 Nutritional/Metabolic factor (feoB) Fe(2+) transporter permease subunit FeoB [FupA (VF0550) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
LPS bplF 0.0000685 2 VF0033 Immune modulation (bplF) lipopolysaccharide biosynthesis protein [LPS (VF0033) - Immune modulation (VFC0258)] [Bordetella pertussis Tohama I]
RatB ratB 0.0000228 1 VF0399 Adherence (ratB) putative outer membrane protein [RatB (VF0399) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
Flagella fliC 0.0000456 2 VF0157 Motility (fliC) flagellin [Flagella (VF0157) - Motility (VFC0204)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
Hsp60 htpB 0.0000456 2 VF0159 Adherence (htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
Beta-haemolysin/cytolysin cylB 0.0002054 9 VF0279 Exotoxin (cylB) ABC (ATP-binding cassette) transporter CylB [Beta-haemolysin/cytolysin (VF0279) - Exotoxin (VFC0235)] [Streptococcus agalactiae NEM316]
ESX-1 eccCa1 0.0000228 1 VF0315 Effector delivery system (eccCa1) ESX-1 type VII secretion system FtsK/SpoIIIE family protein EccCa1 [ESX-1 (VF0315) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
InlC inlC 0.9927647 43,309 VF0438 Immune modulation (inlC) internalin C [InlC (VF0438) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
Pyrimidine biosynthesis carB 0.000388 17 VF0558 Nutritional/Metabolic factor (carB) carbamoyl phosphate synthase large subunit [Pyrimidine biosynthesis (VF0558) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
InlK inlK 1.0171867 43,804 VF0439 Immune modulation (inlK) internalin K [InlK (VF0439) - Immune modulation (VFC0258)] [Listeria monocytogenes EGD-e]
PsaA psaA 0.0000456 2 VF0151 Nutritional/Metabolic factor (psaA) manganese ABC transporter, manganese-binding adhesion liprotein [PsaA (VF0151) - Nutritional/Metabolic factor (VFC0272)] [Streptococcus pneumoniae TIGR4]
O-antigen galE 0.0000456 2 VF0392 Immune modulation (galE) UDP-glucose 4-epimerase GalE [O-antigen (VF0392) - Immune modulation (VFC0258)] [Yersinia enterocolitica subsp. enterocolitica 8081]
Flagella fliM 0.0000456 2 VF0273 Motility (fleR) two-component response regulator [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1]
Flagella motB 0.0001598 4 VF0394 Motility (fliR) flagellar biosynthetic protein FliR [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081]
PspA pspA 0.0000228 1 VF0152 Immune modulation (pspA) surface protein A [PspA (VF0152) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
PlcB plcB 1.0015977 43,804 VF0067 Exotoxin (plcB) phospholipase C [PlcB (VF0067) - Exotoxin (VFC0235)] [Listeria monocytogenes EGD-e]
Pyocyanin phzS 0.0000456 2 VF0100 Nutritional/Metabolic factor (phzS) flavin dependent hydroxylase PhzS [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
Type 1 fimbriae fimH 0.0001369 1 VF0221 Adherence (fimF) FimF protein precursor [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073]
BfmRS bfmR 0.0000228 1 VF0463 Regulation (bfmR) biofilm-controlling response regulator [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU]
ActA actA 1.0126218 43,791 VF0066 Motility (actA) actin-assembly inducing protein precursor [ActA (VF0066) - Motility (VFC0204)] [Listeria monocytogenes EGD-e]
InlA inlA 1.1085066 43,802 VF0069 Invasion (inlA) Internalin A [InlA (VF0069) - Invasion (VFC0083)] [Listeria monocytogenes EGD-e]
Type 1 fimbriae fimH 0.0001369 4 VF0102 Adherence (fimZ) DNA-binding response regulator [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
Capsule galE 0.0000456 2 VF0465 Immune modulation (galE) UDP-glucose 4-epimerase GalE [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
Vi antigen tviB 0.0000913 4 VF0101 Immune modulation (tviB) Vi polysaccharide biosynthesis protein, UDP-N-acetylglucosamine (UPD-GlcNAc) 6-dehydrogenase TviB [Vi antigen (VF0101) - Immune modulation (VFC0258)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
P60 iap/cwhA 1.0015749 43,808 VF0068 Invasion (iap/cwhA) P60 extracellular protein, invasion associated protein Iap [P60 (VF0068) - Invasion (VFC0083)] [Listeria monocytogenes EGD-e]
LpeA lpeA 1.0007076 43,807 VF0346 Invasion (lpeA) lipoprotein promoting cell invasion [LpeA (VF0346) - Invasion (VFC0083)] [Listeria monocytogenes EGD-e]
Pef pefC 0.0000228 1 VF0104 Adherence (pefC) plasmid-encoded fimbriae usher protein PefC [Pef (VF0104) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
Auto aut 0.7200831 29,457 VF0348 Invasion (aut) autolysin [Auto (VF0348) - Invasion (VFC0083)] [Listeria monocytogenes EGD-e]
MgtB mgtB 0.000525 23 VF0106 Nutritional/Metabolic factor (mgtB) Mg2+ transport protein [MgtB (VF0106) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
Chu chuV 0.0000228 1 VF0227 Nutritional/Metabolic factor (chuV) ATP-binding hydrophilic protein ChuV [Chu (VF0227) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
LplA1 lplA1 1.5251638 43,810 VF0347 Nutritional/Metabolic factor (lplA1) lipoate protein ligase [LplA1 (VF0347) - Nutritional/Metabolic factor (VFC0272)] [Listeria monocytogenes EGD-e]
Lpf lpfC 0.0000685 2 VF0105 Adherence (lpfC) long polar fimbrial usher protein LpfC [Lpf (VF0105) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
AdeFGH efflux pump adeG 0.0000228 1 VF0504 Biofilm (adeG) cation/multidrug efflux pump [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
Enterobactin entF 0.0001826 7 VF0228 Nutritional/Metabolic factor (entF) enterobactin synthase multienzyme complex component, ATP-dependent [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
FbpA fbpA 1.0017575 43,812 VF0349 Adherence (fbpA) fibronectin-binding protein [FbpA (VF0349) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
FdeC fdeC 0.0000228 1 VF0506 Adherence (fdeC) adhesin FdeC [FdeC (VF0506) - Adherence (VFC0001)] [Escherichia coli O45:K1:H7 str. S88]
SodCI sodCI 0.0000228 1 VF0109 Stress survival (sodCI) Gifsy-2 prophage: superoxide dismutase precursor (Cu-Zn) [SodCI (VF0109) - Stress survival (VFC0282)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
SMase smcL 0.0000456 2 VF0061 Exoenzyme (smcL) sphingomyelinase-c [SMase (VF0061) - Exoenzyme (VFC0251)] [Listeria ivanovii str. ATCC 19119]
PlcA plcA 1.0002967 43,804 VF0063 Exotoxin (plcA) phosphatidylinositol-specific phospholipase c [PlcA (VF0063) - Exotoxin (VFC0235)] [Listeria monocytogenes EGD-e]
PrfA prfA 1.0009586 43,800 VF0062 Regulation (prfA) listeriolysin positive regulatory protein [PrfA (VF0062) - Regulation (VFC0301)] [Listeria monocytogenes EGD-e]
Mpl mpl 1.0034465 43,804 VF0065 Exoenzyme (mpl) Zinc metalloproteinase precursor [Mpl (VF0065) - Exoenzyme (VFC0251)] [Listeria monocytogenes EGD-e]
EF-Tu tufA 1.0015977 43,808 VF0460 Adherence (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4]
LLO hly 1.0017346 43,804 VF0064 Exotoxin (hly) listeriolysin O precursor [LLO (VF0064) - Exotoxin (VFC0235)] [Listeria monocytogenes EGD-e]
LPS kdtB 0.0000228 1 VF0056 Immune modulation (kdtB) lipopolysaccharide core biosynthesis protein [LPS (VF0056) - Immune modulation (VFC0258)] [Helicobacter pylori 26695]
Allantion utilization allB 0.0002054 8 VF0572 Nutritional/Metabolic factor (allB) allantoinase [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
MtrCDE mtrD 0.0000228 1 VF0451 Antimicrobial activity/Competitive advantage (mtrD) multiple transferable resistance system protein MtrD [MtrCDE (VF0451) - Antimicrobial activity/Competitive advantage (VFC0325)] [Neisseria meningitidis MC58]
KatA katA 0.000913 40 VF0454 Stress survival (katA) catalase [KatA (VF0454) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
T4SS secreted effectors CBU_1566 0.0034921 153 VF0696 Effector delivery system (CBU_1566) Coxiella Dot/Icm type IVB secretion system translocated effector [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493]
SiiE siiE 0.0001369 4 VF0970 Adherence (siiE) non-fimbrial adhesin SiiE [SiiE (VF0970) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
MsrAB msrA/B(pilB 0.6763289 29,613 VF0456 Stress survival (msrA/B(pilB)) trifunctional thioredoxin/methionine sulfoxide reductase A/B protein [MsrAB (VF0456) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
InlP inlP 1.3147239 43,504 VF0577 Adherence (inlP) internalin P [InlP (VF0577) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
Adhesive fimbriae cfaC 0.0000228 1 VF0213 Adherence (cfaC) colonisation factor antigen c, usher [Adhesive fimbriae (VF0213) - Adherence (VFC0001)] [Escherichia coli E24377A]
T6SS rhs/PAAR 0.0002054 4 VF0579 Effector delivery system (rhs/PAAR) Type VI secretion system protein, PAAR family [T6SS (VF0579) - Effector delivery system (VFC0086)] [Shigella sonnei Ss046]
SCI (Salmonella centrisome island)/SPI-6 T6SS STM0274 0.0000456 2 VF0974 Effector delivery system
RecN recN 0.0000456 2 VF0457 Stress survival (recN) DNA repair protein RecN [RecN (VF0457) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
TTSS secreted effectors exoT 0.0000228 1 VF0853 Effector delivery system (exoT) type III secretion system effector ExoT, ADP ribosyltransferase activity and GTPase-activating protein activity [TTSS secreted effectors (VF0853) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
VPS vpsU 0.0000228 1 VF0615 Biofilm (vpsU) exopolysaccharide regulatory protein-tyrosine phosphatase VpsU [VPS (VF0615) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961]
Urease ureG 0.0000913 4 VF0050 Stress survival (ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695]
LPS rfbB 0.000913 39 VF0171 Immune modulation (LPG_RS03745) aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme [LPS (VF0171) - Immune modulation (VFC0258)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
Flagella cheA 0.0000456 2 VF0051 Motility (cheA) histidine kinase CheA [Flagella (VF0051) - Motility (VFC0204)] [Helicobacter pylori 26695]
FarAB farB 0.0000228 1 VF0450 Antimicrobial activity/Competitive advantage (farB) fatty acid efflux system protein FarB [FarAB (VF0450) - Antimicrobial activity/Competitive advantage (VFC0325)] [Neisseria meningitidis MC58]
RcsAB rcsA 0.0000456 2 VF0571 Regulation (rcsA) transcriptional activator for ctr capsule biosynthesis [RcsAB (VF0571) - Regulation (VFC0301)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
Lymphostatin/LifA lifA/efa1 0.0000228 1 VF0175 Effector delivery system (lifA/efa1) lymphostatin Efa1/LifA [Lymphostatin/LifA (VF0175) - Effector delivery system (VFC0086)] [Escherichia coli O55:H7 str. CB9615]