|
FBPs
|
sfbI/prtF1
|
0.0001406 |
1 |
VF0243
|
Adherence |
(sfbX) LPXTG cell wall anchor domain-containing protein [FBPs (VF0243) - Adherence (VFC0001)] [Streptococcus pyogenes MGAS6180]
|
|
Ata
|
ata
|
0.0001406 |
2 |
VF1333
|
Adherence |
(ata) trimeric autotransporter adhesin Ata [Ata (VF1333) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU]
|
|
IcsP (SopA)
|
icsP/sopA
|
0.0000703 |
1 |
VF0122
|
Exoenzyme |
(icsP/sopA) outer membrane protease of the OmpP family, involved in cleavage of surface exposed IcsA [IcsP (SopA) (VF0122) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301]
|
|
Alpha-hemolysin
|
hly/hla
|
0.0000703 |
1 |
VF0001
|
Exotoxin |
(hly/hla) Alpha-Hemolysin precursor [Alpha-hemolysin (VF0001) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
TFP
|
pilG
|
0.8834071 |
12,531 |
VF1334
|
Adherence |
(pilC) type II secretion system F family protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU]
|
|
LPS
|
gtrB
|
0.001265 |
17 |
VF0124
|
Immune modulation |
(gtrB) bactoprenol glucosyl transferase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301]
|
|
Capsule
|
cap8F
|
0.3662239 |
5,171 |
VF0003
|
Immune modulation |
(cap8O) type 8 capsular polysaccharide synthesis protein Cap8O [Capsule (VF0003) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
CbetaG
|
cgs
|
0.0004217 |
6 |
VF0366
|
Immune modulation |
(cgs) cyclic beta 1-2 glucan synthetase [CbetaG (VF0366) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M]
|
|
Aerobactin
|
iutA
|
0.0014759 |
18 |
VF0123
|
Nutritional/Metabolic factor |
(iucC) aerobactin synthesis protein IucC [Aerobactin (VF0123) - Nutritional/Metabolic factor (VFC0272)] [Shigella flexneri 2a str. 301]
|
|
Hyaluronic acid capsule
|
hasC
|
0.0028814 |
36 |
VF0244
|
Immune modulation |
(hasC) UTP--glucose-1-phosphate uridylyltransferase HasC [Hyaluronic acid capsule (VF0244) - Immune modulation (VFC0258)] [Streptococcus pyogenes M1 GAS]
|
|
VirB type IV secretion system
|
virB3
|
0.0026706 |
11 |
VF0365
|
Effector delivery system |
(virB3) type IV secretion system protein VirB3 [VirB type IV secretion system (VF0365) - Effector delivery system (VFC0086)] [Brucella melitensis bv. 1 str. 16M]
|
|
Type I pili
|
fimC
|
0.0000703 |
1 |
VF0486
|
Adherence |
(fimC) outer membrane usher protein [Type I pili (VF0486) - Adherence (VFC0001)] [Aeromonas hydrophila ML09-119]
|
|
Beta-hemolysin
|
hlb
|
0.0000703 |
1 |
VF0002
|
Exotoxin |
(hlb) beta-hemolysin [Beta-hemolysin (VF0002) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus COL]
|
|
CNA
|
cna
|
0.0001406 |
2 |
VF0005
|
Adherence |
(cna) collagen adhesin precursor [CNA (VF0005) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
T6SS
|
vgrG/tssI
|
0.0009136 |
12 |
VF1337
|
Effector delivery system |
(tssC) type VI secretion system contractile sheath large subunit [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU]
|
|
TCP
|
tcpI
|
0.0019678 |
27 |
VF0126
|
Adherence |
(tcpI) negative regulator of the major pilin TcpA [TCP (VF0126) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
BvrR-BvrS
|
bvrR
|
0.0001406 |
2 |
VF0368
|
Regulation |
(bvrR) response regulator transcription factor [BvrR-BvrS (VF0368) - Regulation (VFC0301)] [Brucella melitensis bv. 1 str. 16M]
|
|
Clumping factor
|
clfA
|
0.0002108 |
2 |
VF0004
|
Adherence |
(clfB) Clumping factor B, adhesin [Clumping factor (VF0004) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
LPS
|
wzt
|
1.0281819 |
14,212 |
VF0367
|
Immune modulation |
(gmd) GDP-mannose 4,6-dehydratase [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M]
|
|
T2SS
|
gspE2
|
0.0208729 |
287 |
VF1335
|
Effector delivery system |
(gspE1) general secretion pathway protein E [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU]
|
|
SpeB
|
speB
|
0.0000703 |
1 |
VF0249
|
Exoenzyme |
(speB) pyrogenic exotoxin B [SpeB (VF0249) - Exoenzyme (VFC0251)] [Streptococcus pyogenes M1 GAS]
|
|
ACF
|
acfB
|
0.0011245 |
15 |
VF0127
|
Others |
(acfD) accessory colonization factor AcfD [ACF (VF0127) - Others (VFC0346)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
Spes
|
speG
|
0.0000703 |
1 |
VF0248
|
Exotoxin |
(speG) streptococcal exotoxin G precursor [Spes (VF0248) - Exotoxin (VFC0235)] [Streptococcus pyogenes M1 GAS]
|
|
VirB/VirD4 type IV secretion system
|
virB10
|
0.0000703 |
1 |
VF0369
|
Effector delivery system |
(virB10) type IV secretion system virB10 protein homolog [VirB/VirD4 type IV secretion system (VF0369) - Effector delivery system (VFC0086)] [Bartonella henselae str. Houston-1]
|
|
Exfoliative toxin
|
etb
|
0.0001406 |
1 |
VF0009
|
Exoenzyme |
(etb) exfoliative toxin B [Exfoliative toxin (VF0009) - Exoenzyme (VFC0251)] [Staphylococcus aureus]
|
|
Zot
|
zot
|
0.0104716 |
128 |
VF0129
|
Exotoxin |
(zot) zona occludens toxin [Zot (VF0129) - Exotoxin (VFC0235)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
T6SS
|
atsL
|
0.0248788 |
329 |
VF0480
|
Effector delivery system |
(hcp1) HcpA-like protein [T6SS (VF0480) - Effector delivery system (VFC0086)] [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
|
|
RtxA
|
rtxE
|
0.0004217 |
6 |
VF0482
|
Exotoxin |
(rtxE) RTX toxin transporter, ATPase protein [RtxA (VF0482) - Exotoxin (VFC0235)] [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
|
|
Capsule
|
cpsJ
|
0.0001406 |
2 |
VF0361
|
Immune modulation |
(cpsJ) ABC transporter, ATP-binding protein [Capsule (VF0361) - Immune modulation (VFC0258)] [Enterococcus faecalis V583]
|
|
PhoPQ
|
phoP
|
0.0016164 |
20 |
VF0111
|
Regulation |
(phoP) response regulator in two-component regulatory system with PhoQ [PhoPQ (VF0111) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Lateral flagella
|
lfhA
|
0.0009136 |
12 |
VF0474
|
Motility |
(lfgG) lateral flagellar basal-body rod protein LfgG [Lateral flagella (VF0474) - Motility (VFC0204)] [Aeromonas salmonicida subsp. salmonicida A449]
|
|
Pic
|
pic
|
0.0002108 |
3 |
VF0232
|
Effector delivery system |
(pic) Pic serine protease precursor, autotransporter [Pic (VF0232) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
GroEL
|
groEL
|
0.0014056 |
19 |
VF0594
|
Adherence |
(groEL) chaperonin GroEL [GroEL (VF0594) - Adherence (VFC0001)] [Clostridium difficile 630]
|
|
Sat
|
sat
|
0.0001406 |
2 |
VF0231
|
Effector delivery system |
(sat) Aecreted auto transpoter toxin [Sat (VF0231) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
Polar flagella
|
nueA
|
1.0066062 |
14,207 |
VF0473
|
Motility |
(flrA) FleQ protein [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119]
|
|
AS
|
EF0149
|
0.0001406 |
2 |
VF0352
|
Adherence |
(EF0149) aggregation substance [AS (VF0352) - Adherence (VFC0001)] [Enterococcus faecalis V583]
|
|
Chu
|
chuY
|
0.0005622 |
7 |
VF0234
|
Nutritional/Metabolic factor |
(chuY) ChuY [Chu (VF0234) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli O157:H7 str. EDL933]
|
|
Fur
|
fur
|
0.0015461 |
22 |
VF0113
|
Regulation |
(fur) ferric iron uptake transcriptional regulator [Fur (VF0113) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Tap type IV pili
|
tapC
|
0.001265 |
18 |
VF0475
|
Adherence |
(tapC) type IV fimbrial assembly protein, PilC-like [Tap type IV pili (VF0475) - Adherence (VFC0001)] [Aeromonas hydrophila ML09-119]
|
|
RpoS
|
rpoS
|
0.0008433 |
12 |
VF0112
|
Regulation |
(rpoS) RNA polymerase sigma factor RpoS [RpoS (VF0112) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Tsh
|
tsh
|
0.0000703 |
1 |
VF0233
|
Effector delivery system |
(tsh) temperature-sensitive protein Tsh [Tsh (VF0233) - Effector delivery system (VFC0086)] [Escherichia coli O25b:H4-ST131]
|
|
OmpA
|
ompA
|
0.0010542 |
14 |
VF0236
|
Invasion |
(ompA) outer membrane protein A [OmpA (VF0236) - Invasion (VFC0083)] [Escherichia coli O18:K1:H7 str. RS218]
|
|
Exe T2SS
|
exeA
|
0.001757 |
22 |
VF0478
|
Effector delivery system |
(exeA) general secretion pathway protein A [Exe T2SS (VF0478) - Effector delivery system (VFC0086)] [Aeromonas hydrophila ML09-119]
|
|
MSHA type IV pili
|
mshF
|
0.0000703 |
1 |
VF0477
|
Adherence |
(mshF) hypothetical protein [MSHA type IV pili (VF0477) - Adherence (VFC0001)] [Aeromonas hydrophila ML09-119]
|
|
Flagella
|
eptC
|
0.0000703 |
1 |
VF0114
|
Motility |
(eptC) phosphoethanolamine transferase [Flagella (VF0114) - Motility (VFC0204)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
AslA
|
aslA
|
0.0009839 |
13 |
VF0238
|
Invasion |
(aslA) putative arylsulfatase [AslA (VF0238) - Invasion (VFC0083)] [Escherichia coli O18:K1:H7 str. RS218]
|
|
T3SS
|
ascR
|
0.0009136 |
13 |
VF0479
|
Effector delivery system |
(ascR) Type III secretion system inner membrane export apparatus protein AscR [T3SS (VF0479) - Effector delivery system (VFC0086)] [Aeromonas salmonicida subsp. salmonicida A449]
|
|
Ibes
|
ibeC
|
0.9984539 |
14,140 |
VF0237
|
Invasion |
(ibeB) Cu(+)/Ag(+) efflux RND transporter outer membrane channel CusC [Ibes (VF0237) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
|
|
TTSS (SPI-1 encode)
|
sipB/sspB
|
0.0001406 |
2 |
VF0116
|
Effector delivery system |
(spaP) type III secretion system minor export apparatus protein SpaP [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
K1 capsule
|
kpsD
|
0.0022489 |
25 |
VF0239
|
Invasion |
(kpsD) Polysialic acid transport protein precursor [K1 capsule (VF0239) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88]
|
|
HSI-2 T6SS secreted effectors
|
pldA/tle5a
|
2.175065 |
12,683 |
VF0915
|
Effector delivery system |
(pldA/tle5a) phospholipase D [HSI-2 T6SS secreted effectors (VF0915) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Phospholipase C
|
plc1
|
0.0005622 |
8 |
VF0470
|
Exotoxin |
(plc2) phospholipase C [Phospholipase C (VF0470) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU]
|
|
Salmochelin siderophore
|
iroN
|
0.0037951 |
52 |
VF0230
|
Nutritional/Metabolic factor |
(iroN) salmochelin receptor IroN [Salmochelin siderophore (VF0230) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
PNAG
|
pgaC
|
0.000492 |
7 |
VF0472
|
Biofilm |
(pgaC) poly-beta-1,6 N-acetyl-D-glucosamine synthase [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
PmrAB
|
pmrA
|
0.001757 |
18 |
VF1355
|
Regulation |
(pmrB) sensory kinase PmrB [PmrAB (VF1355) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Capsule
|
cps4J
|
0.0005622 |
8 |
VF0144
|
Immune modulation |
(cps4I) capsular polysaccharide biosynthesis protein Cps4I [Capsule (VF0144) - Immune modulation (VFC0258)] [Streptococcus pneumoniae TIGR4]
|
|
V8 protease
|
sspA
|
0.0000703 |
1 |
VF0023
|
Exoenzyme |
(sspA) serine protease; V8 protease; glutamyl endopeptidase [V8 protease (VF0023) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Hpt
|
hpt
|
0.0000703 |
1 |
VF0264
|
Nutritional/Metabolic factor |
(hpt) hexose phosphate transport protein [Hpt (VF0264) - Nutritional/Metabolic factor (VFC0272)] [Listeria monocytogenes EGD-e]
|
|
Hyaluronidase
|
hysA
|
0.0000703 |
1 |
VF0146
|
Exoenzyme |
(hysA) hyaluronidase [Hyaluronidase (VF0146) - Exoenzyme (VFC0251)] [Streptococcus pneumoniae TIGR4]
|
|
TTSS secreted effectors
|
espR1
|
0.0001406 |
1 |
VF1111
|
Effector delivery system |
(espX5) Type III secretion system effector EspX5 [TTSS secreted effectors (VF1111) - Effector delivery system (VFC0086)] [Escherichia coli O55:H7 str. CB9615]
|
|
Vat
|
vat
|
0.0002811 |
3 |
VF1112
|
Effector delivery system |
(vat) vacuolating autotransporter toxin [Vat (VF1112) - Effector delivery system (VFC0086)] [Escherichia coli CFT073]
|
|
Aureolysin
|
aur
|
0.0002108 |
2 |
VF0024
|
Exoenzyme |
(aur) zinc metalloproteinase aureolysin [Aureolysin (VF0024) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
HitABC
|
hitC
|
0.0000703 |
1 |
VF0268
|
Nutritional/Metabolic factor |
(hitC) iron(III) ABC transporter, ATP-binding protein [HitABC (VF0268) - Nutritional/Metabolic factor (VFC0272)] [Haemophilus influenzae Rd KW20]
|
|
Cya
|
cyaB
|
0.0610022 |
862 |
VF0028
|
Exotoxin |
(cyaB) cyclolysin secretion ATP-binding protein [Cya (VF0028) - Exotoxin (VFC0235)] [Bordetella pertussis Tohama I]
|
|
HSI-3
|
tssK
|
14.9132757 |
14,034 |
VF0944
|
Effector delivery system |
(tssI) type VI secretion system tip protein VgrG [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
HSI-2
|
tssJ
|
21.2649519 |
14,224 |
VF0943
|
Effector delivery system |
(PA1663) transcriptional regulator [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
CsrA
|
csrA
|
1.0593858 |
14,173 |
VF0261
|
Regulation |
(csrA) carbon storage regulator CsrA [CsrA (VF0261) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
RelA
|
relA
|
0.0000703 |
1 |
VF0260
|
Regulation |
(relA) GTP diphosphokinase [RelA (VF0260) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
TTSS secreted effectors
|
espL1
|
0.0002108 |
1 |
VF1110
|
Effector delivery system |
(espX4) Type III secretion system effector EspX4 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933]
|
|
Staphylokinase
|
sak
|
0.0000703 |
1 |
VF0021
|
Exoenzyme |
(sak) Staphylokinase precursor [Staphylokinase (VF0021) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
HSI-3 T6SS secreted effectors
|
pldB/tle5b
|
1.0052006 |
13,937 |
VF1350
|
Effector delivery system |
(pldB/tle5b) phospholipase D [HSI-3 T6SS secreted effectors (VF1350) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
LetA/S
|
letA
|
0.000492 |
7 |
VF0262
|
Regulation |
(letA) UvrY/SirA/GacA family response regulator transcription factor [LetA/S (VF0262) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
SE
|
selq
|
0.0000703 |
1 |
VF0020
|
Exotoxin |
(selq) staphylococcal enterotoxin G precursor [SE (VF0020) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Lipase
|
lip
|
0.0002811 |
2 |
VF0012
|
Exoenzyme |
(lip) triacylglycerol lipase precursor [Lipase (VF0012) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
BoNT
|
bont
|
0.0000703 |
1 |
VF0375
|
Exotoxin |
(bont) botulinum neurotoxin, BoNT [BoNT (VF0375) - Exotoxin (VFC0235)] [Clostridium botulinum C str. Stockholm]
|
|
Isocitrate lyase
|
icl
|
0.0013353 |
18 |
VF0253
|
Others |
(icl) Isocitrate lyase Icl (isocitrase) (isocitratase) [Isocitrate lyase (VF0253) - Others (VFC0346)] [Mycobacterium tuberculosis H37Rv]
|
|
Gamma-hemolysin
|
hlgA
|
0.0002108 |
1 |
VF0011
|
Exotoxin |
(hlgA) gamma-hemolysin chain II precursor [Gamma-hemolysin (VF0011) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Intercellular adhesion proteins
|
icaB
|
0.0004217 |
2 |
VF0014
|
Biofilm |
(icaR) ica operon transcriptional regulator IcaR [Intercellular adhesion proteins (VF0014) - Biofilm (VFC0271)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Shu
|
shuV
|
0.0004217 |
6 |
VF0256
|
Nutritional/Metabolic factor |
(shuA) outer membrane heme/hemoglobin receptor ShuA [Shu (VF0256) - Nutritional/Metabolic factor (VFC0272)] [Shigella dysenteriae Sd197]
|
|
Hyaluronate lyase
|
hysA
|
0.0001406 |
1 |
VF0013
|
Exoenzyme |
(hysA) hyaluronate lyase precursor [Hyaluronate lyase (VF0013) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Eap/Map
|
eap/map
|
0.0000703 |
1 |
VF0016
|
Adherence |
(eap/map) extracellular adherence protein Eap/Map [Eap/Map (VF0016) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
ShET2
|
senB
|
0.0000703 |
1 |
VF0258
|
Exotoxin |
(senB) enterotoxin [ShET2 (VF0258) - Exotoxin (VFC0235)] [Shigella boydii Sb227]
|
|
SigA
|
sigA/rpoV
|
0.0011947 |
17 |
VF0257
|
Regulation |
(sigA/rpoV) RNA polymerase sigma factor SigA [SigA (VF0257) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
Yersiniabactin
|
ybtS
|
0.0156019 |
101 |
VF0136
|
Nutritional/Metabolic factor |
(irp1) yersiniabactin biosynthetic protein Irp1 [Yersiniabactin (VF0136) - Nutritional/Metabolic factor (VFC0272)] [Yersinia pestis CO92]
|
|
Isd
|
isdA
|
0.0007028 |
1 |
VF0015
|
Nutritional/Metabolic factor |
(harA) haptoglobin-binding heme uptake protein HarA [Isd (VF0015) - Nutritional/Metabolic factor (VFC0272)] [Staphylococcus aureus subsp. aureus str. Newman]
|
|
SpA
|
spa
|
0.0002108 |
3 |
VF0017
|
Exotoxin |
(spa) Immunoglobulin G binding protein A precursor [SpA (VF0017) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
RtxA
|
rtxA
|
0.0000703 |
1 |
VF0259
|
Exotoxin |
(rtxA) structural toxin protein RtxA [RtxA (VF0259) - Exotoxin (VFC0235)] [Legionella pneumophila str. Paris]
|
|
SDr
|
sdrE
|
0.0006325 |
3 |
VF0019
|
Adherence |
(sdrC) Ser-Asp rich fibrinogen-binding bone sialoprotein-binding protein [SDr (VF0019) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
SLO
|
slo
|
0.0000703 |
1 |
VF0250
|
Exotoxin |
(slo) streptolysin O precursor [SLO (VF0250) - Exotoxin (VFC0235)] [Streptococcus pyogenes M1 GAS]
|
|
LPS
|
fabZ
|
0.0000703 |
1 |
VF0370
|
Immune modulation |
(fabZ) 3-hydroxyacyl-ACP dehydratase FabZ [LPS (VF0370) - Immune modulation (VFC0258)] [Bartonella henselae str. Houston-1]
|
|
Flagella
|
flgG
|
0.0002108 |
3 |
VF0373
|
Motility |
(flaA) flagellin A [Flagella (VF0373) - Motility (VFC0204)] [Bartonella bacilliformis KC583]
|
|
FnBPs
|
fnbA
|
0.0002108 |
1 |
VF0010
|
Adherence |
(fnbA) fibronectin-binding protein A [FnBPs (VF0010) - Adherence (VFC0001)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Trw type IV secretion system
|
trwK
|
0.0074496 |
60 |
VF0372
|
Effector delivery system |
(trwE) Trw type IV secretion sysmtem VirB10 homolog, trwE protein [Trw type IV secretion system (VF0372) - Effector delivery system (VFC0086)] [Bartonella henselae str. Houston-1]
|
|
Ent
|
entS
|
1.0088552 |
14,132 |
VF0562
|
Nutritional/Metabolic factor |
(entD) enterochelin synthetase component D [Ent (VF0562) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
LPS
|
rfbB
|
0.0004217 |
6 |
VF0561
|
Immune modulation |
(rfbA) O-antigen export ABC transporter permease RfbA [LPS (VF0561) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Ybt
|
ybtS
|
0.0088552 |
79 |
VF0564
|
Nutritional/Metabolic factor |
(ybtE) yersiniabactin biosynthesis salycil-AMP ligase YbtE [Ybt (VF0564) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Sal
|
iroN
|
0.9794083 |
13,904 |
VF0563
|
Nutritional/Metabolic factor |
(iroN) salmochelin receptor IroN [Sal (VF0563) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Type I fimbriae
|
fimI
|
0.0072387 |
44 |
VF0566
|
Adherence |
(fimG) type 1 fimbrial minor component [Type I fimbriae (VF0566) - Adherence (VFC0001)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Aerobactin
|
iutA
|
0.003514 |
31 |
VF0565
|
Nutritional/Metabolic factor |
(iucC) aerobactin siderophore biosynthesis protein IucC [Aerobactin (VF0565) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Lap
|
lap
|
0.0004217 |
5 |
VF0444
|
Adherence |
(lap) Listeria adhesion protein Lap [Lap (VF0444) - Adherence (VFC0001)] [Listeria monocytogenes EGD-e]
|
|
Capsule
|
kpsF
|
0.0002811 |
4 |
VF0323
|
Immune modulation |
(kpsF) D-arabinose 5-phosphate isomerase [Capsule (VF0323) - Immune modulation (VFC0258)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
|
|
AcrAB
|
acrA
|
1.0702087 |
14,212 |
VF0568
|
Antimicrobial activity/Competitive advantage |
(acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Type 3 fimbriae
|
mrkI
|
0.0040059 |
31 |
VF0567
|
Biofilm |
(mrkC) fimbrial biogenesis outer membrane usher protein mrkC precursor [Type 3 fimbriae (VF0567) - Biofilm (VFC0271)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
T6SS
|
vipA/tssB
|
0.0177806 |
110 |
VF0569
|
Effector delivery system |
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF0569) - Effector delivery system (VFC0086)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Capsule
|
wcaJ
|
0.0118772 |
106 |
VF0560
|
Immune modulation |
(KP1_RS17305) GDP-L-fucose synthase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Flagella
|
cheD
|
1.0278305 |
14,175 |
VF0430
|
Motility |
(tsr) methyl-accepting chemotaxis protein I [Flagella (VF0430) - Motility (VFC0204)] [Burkholderia pseudomallei K96243]
|
|
FupA
|
feoB
|
0.0003514 |
5 |
VF0550
|
Nutritional/Metabolic factor |
(feoB) Fe(2+) transporter permease subunit FeoB [FupA (VF0550) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
GGT
|
ggt
|
0.0009136 |
13 |
VF0553
|
Nutritional/Metabolic factor |
(ggt) gamma-glutamyltranspeptidase [GGT (VF0553) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
BoaA
|
boaA
|
0.0000703 |
1 |
VF0434
|
Adherence |
(boaA) surface-exposed protein, autotransporter [BoaA (VF0434) - Adherence (VFC0001)] [Burkholderia pseudomallei K96243]
|
|
Capsule I
|
wcbT
|
0.0008433 |
11 |
VF0436
|
Immune modulation |
(wcbB) capsular polysaccharide glycosyltransferase biosynthesis protein [Capsule I (VF0436) - Immune modulation (VFC0258)] [Burkholderia pseudomallei K96243]
|
|
ESX-1
|
eccCb1
|
0.0000703 |
1 |
VF0315
|
Effector delivery system |
(eccCb1) ESX-1 type VII secretion system FtsK/SpoIIIE family protein EccCb1 [ESX-1 (VF0315) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
Dot/Icm T4SS secreted effectors
|
LPG_RS11860
|
0.0006325 |
9 |
VF0798
|
Effector delivery system |
(LPG_RS11860) Dot/Icm type IV secretion system effector [Dot/Icm T4SS secreted effectors (VF0798) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Pyrimidine biosynthesis
|
carB
|
0.0144072 |
184 |
VF0558
|
Nutritional/Metabolic factor |
(carA) carbamoyl phosphate synthase small subunit [Pyrimidine biosynthesis (VF0558) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
PanC/PanD
|
panC
|
0.0002108 |
3 |
VF0319
|
Nutritional/Metabolic factor |
(panC) pantothenate synthetase [PanC/PanD (VF0319) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
Pyocyanin
|
phzS
|
16.0870054 |
14,225 |
VF0100
|
Nutritional/Metabolic factor |
(phzS) flavin dependent hydroxylase PhzS [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
Type 1 fimbriae
|
fimH
|
0.0007731 |
11 |
VF0221
|
Adherence |
(fimG) FimG protein precursor [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
BfmRS
|
bfmS
|
1.0065359 |
14,203 |
VF0463
|
Regulation |
(bfmS) signal transduction histidine kinase [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU]
|
|
P fimbriae
|
papC
|
0.0000703 |
1 |
VF0220
|
Adherence |
(papC) usher protein PapC [P fimbriae (VF0220) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
Dr adhesins
|
draA
|
0.0007028 |
7 |
VF0223
|
Adherence |
(draC) usher protein DraC [Dr adhesins (VF0223) - Adherence (VFC0001)] [Escherichia coli O75:K5:H- str. IH11128]
|
|
Bacillibactin
|
dhbF
|
0.0044276 |
62 |
VF0586
|
Nutritional/Metabolic factor |
(dhbE) 2,3-dihydroxybenzoate adenylase DhbE [Bacillibactin (VF0586) - Nutritional/Metabolic factor (VFC0272)] [Bacillus cereus ATCC 10987]
|
|
Type 1 fimbriae
|
fimI
|
0.0009136 |
5 |
VF0102
|
Adherence |
(fimW) helix-turn-helix transcriptional regulator [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Capsule
|
pseF
|
0.3921569 |
3,828 |
VF0465
|
Immune modulation |
(ACICU_RS00500) phosphomannomutase/phosphoglucomutase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Vi antigen
|
tviC
|
0.2306557 |
3,261 |
VF0101
|
Immune modulation |
(tviB) Vi polysaccharide biosynthesis protein, UDP-N-acetylglucosamine (UPD-GlcNAc) 6-dehydrogenase TviB [Vi antigen (VF0101) - Immune modulation (VFC0258)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
|
|
S fimbriae
|
sfaF
|
0.0000703 |
1 |
VF0222
|
Adherence |
(sfaF) S fimbriae outer membrane usher SfaF [S fimbriae (VF0222) - Adherence (VFC0001)] [Escherichia coli UTI89]
|
|
Alpha-Hemolysin
|
hlyB
|
0.0007028 |
10 |
VF0225
|
Exotoxin |
(hlyB) Hemolysin B [Alpha-Hemolysin (VF0225) - Exotoxin (VFC0235)] [Escherichia coli CFT073]
|
|
Acinetobactin
|
bauD
|
0.037037 |
179 |
VF0467
|
Nutritional/Metabolic factor |
(basB) non-ribosomal peptide synthetase with condensation and peptidyl carrier protein domains [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU]
|
|
Pef
|
pefC
|
0.0001406 |
1 |
VF0104
|
Adherence |
(pefD) plasmid-encoded fimbriae chaperone protein PefD [Pef (VF0104) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
LPS
|
lpxL
|
0.0011947 |
16 |
VF0466
|
Immune modulation |
(lpxA) acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Agf
|
csgE
|
0.0002811 |
2 |
VF0103
|
Adherence |
(csgF) curli production assembly/transport protein CsgF [Agf (VF0103) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
F1C fimbriae
|
sfaY
|
0.0000703 |
1 |
VF0224
|
Adherence |
(sfaY) transcriptional regulator SfaY [F1C fimbriae (VF0224) - Adherence (VFC0001)] [Escherichia coli CFT073]
|
|
Phospholipase D
|
plcD
|
0.0000703 |
1 |
VF0469
|
Exotoxin |
(plcD) phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase [Phospholipase D (VF0469) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU]
|
|
MgtB
|
mgtB
|
1.0098391 |
14,195 |
VF0106
|
Nutritional/Metabolic factor |
(mgtB) Mg2+ transport protein [MgtB (VF0106) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Chu
|
chuX
|
0.001757 |
19 |
VF0227
|
Nutritional/Metabolic factor |
(chuT) periplasmic heme-binding protein ChuT [Chu (VF0227) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
Lpf
|
lpfC
|
0.0001406 |
2 |
VF0105
|
Adherence |
(lpfC) long polar fimbrial usher protein LpfC [Lpf (VF0105) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
PbpG
|
pbpG
|
0.0000703 |
1 |
VF0468
|
Immune modulation |
(pbpG) D-alanyl-D-alanine endopeptidase PBP7/8 [PbpG (VF0468) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU]
|
|
Aerobactin
|
iutA
|
0.0010542 |
13 |
VF0229
|
Nutritional/Metabolic factor |
(iutA) ferric aerobactin receptor precusor IutA [Aerobactin (VF0229) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
Enterobactin
|
entS
|
1.0007731 |
13,991 |
VF0228
|
Nutritional/Metabolic factor |
(entE) 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073]
|
|
Csu fimbriae
|
csuD
|
0.0005622 |
8 |
VF0461
|
Biofilm |
(csuD) Csu pilus usher protein CsuD [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
Exolysin
|
exlB
|
0.0123691 |
85 |
VF0582
|
Effector delivery system |
(exlA) hemolysin [Exolysin (VF0582) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PA7]
|
|
EF-Tu
|
tufA
|
2.7272472 |
14,168 |
VF0460
|
Adherence |
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Colibactin
|
clbG
|
0.0033734 |
18 |
VF0573
|
Exotoxin |
(clbC) colibactin polyketide synthase ClbC [Colibactin (VF0573) - Exotoxin (VFC0235)] [Klebsiella pneumoniae subsp. pneumoniae 1084]
|
|
Allantion utilization
|
allB
|
0.0024598 |
27 |
VF0572
|
Nutritional/Metabolic factor |
(allB) allantoinase [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
MtrCDE
|
mtrE
|
0.007309 |
92 |
VF0451
|
Antimicrobial activity/Competitive advantage |
(mtrC) membrane fusion protein MtrC [MtrCDE (VF0451) - Antimicrobial activity/Competitive advantage (VFC0325)] [Neisseria meningitidis MC58]
|
|
T2SS
|
gspD
|
0.0047087 |
46 |
VF0333
|
Effector delivery system |
(gspE) general secretion pathway protein E [T2SS (VF0333) - Effector delivery system (VFC0086)] [Shigella dysenteriae Sd197]
|
|
T4SS secreted effectors
|
coxH2/rimL
|
0.9993675 |
14,184 |
VF0696
|
Effector delivery system |
(CBU_0270) Coxiella Dot/Icm type IVB secretion system translocated effector, trans-2-enoyl-CoA reductase [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493]
|
|
KatA
|
katA
|
1.1929159 |
14,203 |
VF0454
|
Stress survival |
(katA) catalase [KatA (VF0454) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
Invasin C/Ilp
|
invC/ilp
|
0.0000703 |
1 |
VF0575
|
Invasion |
(invC/ilp) intimin-like invasin C protein [Invasin C/Ilp (VF0575) - Invasion (VFC0083)] [Yersinia pseudotuberculosis IP 31758]
|
|
T4SS secreted effectors
|
ricA
|
0.000492 |
7 |
VF0695
|
Effector delivery system |
(ricA) type IV secretion system effector RicA, Rab2 interacting conserved protein A [T4SS secreted effectors (VF0695) - Effector delivery system (VFC0086)] [Brucella melitensis bv. 1 str. 16M]
|
|
MsrAB
|
msrA/B(pilB
|
0.0358423 |
496 |
VF0456
|
Stress survival |
(msrA/B(pilB)) trifunctional thioredoxin/methionine sulfoxide reductase A/B protein [MsrAB (VF0456) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
VAS T6SS
|
hcp-1
|
0.0094174 |
126 |
VF0335
|
Effector delivery system |
(vasH) type VI secretion system regulatory protein VasH [VAS T6SS (VF0335) - Effector delivery system (VFC0086)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
AAFs
|
aafD
|
0.0000703 |
1 |
VF0214
|
Adherence |
(aafD) chaperone protein AafD [AAFs (VF0214) - Adherence (VFC0001)] [Escherichia coli O44:H18 042]
|
|
Adhesive fimbriae
|
cfaD/cfaE
|
0.0000703 |
1 |
VF0213
|
Adherence |
(cfaD/cfaE) minor pilin and initiator [Adhesive fimbriae (VF0213) - Adherence (VFC0001)] [Escherichia coli E24377A]
|
|
MntABC
|
mntB
|
0.0004217 |
5 |
VF0455
|
Stress survival |
(mntB) Manganese transport system membrane protein MntB [MntABC (VF0455) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
HSI-1
|
icmF1/tssM1
|
25.0644459 |
14,224 |
VF0334
|
Effector delivery system |
(hsiF1/tssE) type VI secretion system hcp secretion island protein HsiF1, a gp25-like protein, but not exhibit lysozyme activity [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
T6SS
|
tssJ
|
0.0047087 |
27 |
VF0579
|
Effector delivery system |
(tssG) Type VI secretion system protein TssG [T6SS (VF0579) - Effector delivery system (VFC0086)] [Shigella sonnei Ss046]
|
|
RecN
|
recN
|
0.0005622 |
8 |
VF0457
|
Stress survival |
(recN) DNA repair protein RecN [RecN (VF0457) - Stress survival (VFC0282)] [Neisseria meningitidis MC58]
|
|
BvgAS
|
bvgA
|
0.004779 |
65 |
VF0336
|
Regulation |
(bvgS) virulence factors two-component system sensor histidine kinase BvgS [BvgAS (VF0336) - Regulation (VFC0301)] [Bordetella pertussis Tohama I]
|
|
Pet
|
pet
|
0.0002108 |
3 |
VF0217
|
Effector delivery system |
(pet) Pet serine protease precursor, autotransporter [Pet (VF0217) - Effector delivery system (VFC0086)] [Escherichia coli O44:H18 042]
|
|
FarAB
|
farB
|
0.004779 |
68 |
VF0450
|
Antimicrobial activity/Competitive advantage |
(farA) fatty acid efflux system protein FarA [FarAB (VF0450) - Antimicrobial activity/Competitive advantage (VFC0325)] [Neisseria meningitidis MC58]
|
|
RcsAB
|
rcsB
|
0.0063954 |
88 |
VF0571
|
Regulation |
(rcsA) transcriptional activator for ctr capsule biosynthesis [RcsAB (VF0571) - Regulation (VFC0301)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
|
|
Rhamnolipid
|
rhlC
|
3.2722609 |
14,215 |
VF0089
|
Immune modulation |
(rhlA) rhamnosyltransferase chain A [Rhamnolipid (VF0089) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1]
|
|
LasA
|
lasA
|
1.088411 |
14,156 |
VF0088
|
Effector delivery system |
(lasA) LasA protease precursor [LasA (VF0088) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Type IV pili
|
pilU
|
0.0044979 |
58 |
VF0401
|
Adherence |
(pilO) type IV pilus inner membrane platform protein PilO [Type IV pili (VF0401) - Adherence (VFC0001)] [Yersinia pseudotuberculosis IP 31758]
|
|
SinH
|
sinH
|
0.0007731 |
10 |
VF0400
|
Adherence |
(sinH) intimin-like protein [SinH (VF0400) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Type VII secretion system
|
esaB
|
0.001265 |
3 |
VF0403
|
Effector delivery system |
(esaB) type VII secretion system protein EsaB [Type VII secretion system (VF0403) - Effector delivery system (VFC0086)] [Staphylococcus aureus subsp. aureus MW2]
|
|
ESX-5
|
PPE25
|
0.0001406 |
1 |
VF0402
|
Effector delivery system |
(PPE25) PPE family protein PPE25 [ESX-5 (VF0402) - Effector delivery system (VFC0086)] [Mycobacterium tuberculosis H37Rv]
|
|
ECP
|
ykgK/ecpR
|
0.0078712 |
72 |
VF0404
|
Adherence |
(ykgK/ecpR) regulator protein EcpR [ECP (VF0404) - Adherence (VFC0001)] [Escherichia coli O157:H7 str. EDL933]
|
|
AI-2
|
luxS
|
0.0004217 |
6 |
VF0406
|
Biofilm |
(luxS) S-ribosylhomocysteinase [AI-2 (VF0406) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
RlrA islet
|
rrgC
|
0.0000703 |
1 |
VF0529
|
Adherence |
(rrgC) cell wall surface anchor family protein, minor pili RrgC [RlrA islet (VF0529) - Adherence (VFC0001)] [Streptococcus pneumoniae TIGR4]
|
|
T3SS1
|
vscN
|
0.0000703 |
1 |
VF0408
|
Effector delivery system |
(vscN) type III secretion system ATPase VscN [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633]
|
|
TTSS
|
pcr3
|
36.8489001 |
14,143 |
VF0083
|
Effector delivery system |
(pscQ) type III secretion system protein PscQ [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Type IV pili
|
vfr
|
37.2995291 |
14,229 |
VF0082
|
Adherence |
(pilY1) type 4 fimbrial biogenesis protein PilY1 [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1]
|
|
LPS
|
PA3143
|
9.4263125 |
14,226 |
VF0085
|
Immune modulation |
(wbpJ) glycosyl transferase WbpJ [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1]
|
|
Xcp secretion system
|
xcpP
|
11.7439736 |
14,223 |
VF0084
|
Effector delivery system |
(xcpP) secretion protein XcpP [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
LasB
|
lasB
|
1.0154614 |
14,206 |
VF0087
|
Effector delivery system |
(lasB) elastase LasB [LasB (VF0087) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
ExoA
|
toxA
|
1.0028112 |
13,934 |
VF0086
|
Exotoxin |
(toxA) exotoxin A precursor [ExoA (VF0086) - Exotoxin (VFC0235)] [Pseudomonas aeruginosa PAO1]
|
|
LOS
|
rfaK
|
0.0000703 |
1 |
VF0078
|
Immune modulation |
(rfaK) glycosyltransferase family 4 protein [LOS (VF0078) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
SSLs
|
set24
|
0.0007028 |
1 |
VF0990
|
Exotoxin |
(set19) superantigen-like protein SSL4 [SSLs (VF0990) - Exotoxin (VFC0235)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Capsule
|
ctrD
|
0.0001406 |
2 |
VF0079
|
Immune modulation |
(lipB) capsule polysaccharide modification protein LipB [Capsule (VF0079) - Immune modulation (VFC0258)] [Neisseria meningitidis MC58]
|
|
IlpA
|
IlpA
|
0.0007028 |
10 |
VF0513
|
Adherence |
(IlpA) immunogenic lipoprotein A [IlpA (VF0513) - Adherence (VFC0001)] [Vibrio vulnificus YJ016]
|
|
VAS T6SS secreted effectors
|
vgrG-1
|
0.0001406 |
2 |
VF0634
|
Effector delivery system |
(vgrG-1) type VI secretion system tip protein VgrG [VAS T6SS secreted effectors (VF0634) - Effector delivery system (VFC0086)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
MAM7
|
mam7
|
0.0005622 |
8 |
VF0512
|
Adherence |
(mam7) multivalent adhesion molecule MAM7 [MAM7 (VF0512) - Adherence (VFC0001)] [Vibrio parahaemolyticus RIMD 2210633]
|
|
MSHA pili
|
mshA
|
0.0000703 |
1 |
VF0515
|
Adherence |
(mshA) MSHA pilin protein MshA [MSHA pili (VF0515) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
HemO cluster
|
ACICU_RS04565
|
0.0003514 |
5 |
VF0636
|
Nutritional/Metabolic factor |
(hemO) biliverdin-producing heme oxygenase [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU]
|
|
Yst1 T2SS
|
yst1F
|
0.0007731 |
11 |
VF0635
|
Effector delivery system |
(yst1E) type II secretion system ATPase GspE [Yst1 T2SS (VF0635) - Effector delivery system (VFC0086)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Flagella
|
flrA
|
0.0005622 |
8 |
VF0519
|
Motility |
(flaA) flagellin [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
ClpC
|
clpC
|
0.0066062 |
73 |
VF0072
|
Stress survival |
(clpC) endopeptidase Clp ATP-binding chain C [ClpC (VF0072) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
ClpP
|
clpP
|
0.9989458 |
14,190 |
VF0074
|
Stress survival |
(clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
ClpE
|
clpE
|
0.0002108 |
2 |
VF0073
|
Stress survival |
(clpE) ATP-dependent protease [ClpE (VF0073) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e]
|
|
Opa
|
opa
|
0.0000703 |
1 |
VF0076
|
Invasion |
(opa) outer membrane beta-barrel protein [Opa (VF0076) - Invasion (VFC0083)] [Neisseria meningitidis MC58]
|
|
Type IV pili
|
pilG
|
0.0015461 |
22 |
VF0075
|
Adherence |
(pilS) pilin [Type IV pili (VF0075) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
|
|
LPS
|
wbtL
|
1.0013353 |
14,174 |
VF0542
|
Immune modulation |
(wbtF) NAD dependent epimerase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
Staphylocoagulase
|
coa
|
0.0000703 |
1 |
VF0421
|
Exoenzyme |
(coa) staphylocoagulase precursor [Staphylocoagulase (VF0421) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus MW2]
|
|
VWbp
|
vWbp
|
0.0000703 |
1 |
VF0420
|
Exoenzyme |
(vWbp) secreted von Willebrand factor-binding protein precursor [VWbp (VF0420) - Exoenzyme (VFC0251)] [Staphylococcus aureus subsp. aureus str. Newman]
|
|
Nitrate reductase
|
narI
|
0.0140558 |
187 |
VF0302
|
Nutritional/Metabolic factor |
(narG) nitrate reductase subunit alpha [Nitrate reductase (VF0302) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
Sbi
|
sbi
|
0.0000703 |
1 |
VF0423
|
Immune modulation |
(sbi) IgG-binding protein SBI [Sbi (VF0423) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
Capsule
|
galE
|
0.9990161 |
14,201 |
VF0543
|
Immune modulation |
(galE) UDP-glucose 4-epimerase GalE [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4]
|
|
AdsA
|
adsA
|
0.0002108 |
3 |
VF0422
|
Immune modulation |
(adsA) Adenosine synthase A [AdsA (VF0422) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2]
|
|
KatG
|
katG
|
0.0003514 |
5 |
VF0303
|
Stress survival |
(katG) catalase-peroxidase [KatG (VF0303) - Stress survival (VFC0282)] [Mycobacterium tuberculosis H37Rv]
|
|
Bsa T3SS
|
bsaQ
|
0.0000703 |
1 |
VF0428
|
Effector delivery system |
(bsaQ) Type III secretion system protein BsaQ [Bsa T3SS (VF0428) - Effector delivery system (VFC0086)] [Burkholderia pseudomallei K96243]
|
|
PDIM
|
pks15
|
0.00253 |
23 |
VF0309
|
Immune modulation |
(ddrA) daunorubicin ABC transporter ATP-binding protein DrrA [PDIM (VF0309) - Immune modulation (VFC0258)] [Mycobacterium tuberculosis H37Rv]
|
|
HSI-1 T6SS secreted effectors
|
tse6
|
6.1624851 |
14,221 |
VF1194
|
Effector delivery system |
(tse3) type VI secretion system effector Tse3, glycoside hydrolase [HSI-1 T6SS secreted effectors (VF1194) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
Fap
|
fapD
|
5.9579732 |
14,111 |
VF1191
|
Adherence |
(fapF) outer membrane secretin FapF [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1]
|
|
T6SS secreted effectors
|
vgrG1
|
0.0018975 |
24 |
VF0651
|
Effector delivery system |
(vgrG1) Type VI secretion system effector VgrG1, ADP-ribosyltransferase [T6SS secreted effectors (VF0651) - Effector delivery system (VFC0086)] [Aeromonas hydrophila subsp. hydrophila ATCC 7966]
|
|
RTX protein
|
frpA
|
0.0009839 |
14 |
VF0897
|
Adherence |
(frpA) iron-regulated protein FrpA [RTX protein (VF0897) - Adherence (VFC0001)] [Neisseria meningitidis MC58]
|
|
EcbA
|
ecbA/fss3
|
0.0002108 |
2 |
VF0539
|
Adherence |
(ecbA/fss3) Collagen binding MSCRAMM, EcbA/Fss3 [EcbA (VF0539) - Adherence (VFC0001)] [Enterococcus faecium DO]
|
|
Ebp pili
|
ebpA
|
0.0000703 |
1 |
VF0538
|
Adherence |
(ebpA) endocarditis and biofilm-associated pilus tip protein EbpA [Ebp pili (VF0538) - Adherence (VFC0001)] [Enterococcus faecalis V583]
|
|
Alkaline protease
|
aprA
|
1.0002108 |
14,163 |
VF0090
|
Exoenzyme |
(aprA) alkaline metalloproteinase precursor [Alkaline protease (VF0090) - Exoenzyme (VFC0251)] [Pseudomonas aeruginosa PAO1]
|
|
PLC
|
plcH
|
1.0082226 |
14,179 |
VF0092
|
Exotoxin |
(plcH) hemolytic phospholipase C precursor [PLC (VF0092) - Exotoxin (VFC0235)] [Pseudomonas aeruginosa PAO1]
|
|
Alginate
|
algI
|
25.7803078 |
14,229 |
VF0091
|
Biofilm |
(algL) poly(beta-d-mannuronate) lyase precursor AlgL [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
Pyoverdine
|
PA2384
|
26.9800408 |
14,207 |
VF0094
|
Nutritional/Metabolic factor |
(PA2384) hypothetical protein [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
Quorum sensing
|
rhlI
|
3.9576218 |
14,216 |
VF0093
|
Biofilm |
(lasI) autoinducer synthesis protein LasI [Quorum sensing (VF0093) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1]
|
|
Pyochelin
|
pchI
|
14.4933586 |
14,223 |
VF0095
|
Nutritional/Metabolic factor |
(pchB) salicylate biosynthesis protein PchB [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1]
|
|
RelA
|
relA
|
0.0000703 |
1 |
VF0287
|
Regulation |
(relA) Probable GTP pyrophosphokinase RelA (ATP:GTP 3'-pyrophosphotransferase) (PPGPP synthetase I) ((P)PPGPP synthetase) (GTP diphosphokinase) [RelA (VF0287) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
PhoP
|
phoP
|
0.0001406 |
2 |
VF0286
|
Regulation |
(phoP) Possible two component system response transcriptional positive regulator PhoP [PhoP (VF0286) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
LOS
|
rffG
|
1.0855296 |
14,205 |
VF0044
|
Immune modulation |
(msbA) lipid transporter ATP-binding/permease [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20]
|
|
KatAB
|
katA
|
0.0026706 |
37 |
VF0168
|
Stress survival |
(katA) catalase/(hydro)peroxidase [KatAB (VF0168) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
MgtC
|
mgtC
|
0.0014759 |
21 |
VF0289
|
Nutritional/Metabolic factor |
(mgtC) Possible Mg2+ transport P-type ATPase C MgtC [MgtC (VF0289) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
GspA
|
LPG_RS11000
|
0.0003514 |
5 |
VF0167
|
Stress survival |
(LPG_RS11000) Hsp20 family protein [GspA (VF0167) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Tbp
|
tbpA
|
0.0001406 |
1 |
VF0046
|
Nutritional/Metabolic factor |
(tbpA) transferrin-binding protein A [Tbp (VF0046) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
SodB
|
sodB
|
1.0041465 |
14,204 |
VF0169
|
Stress survival |
(sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
DIP0733
|
DIP_RS14950
|
0.0000703 |
1 |
VF0601
|
Adherence |
(DIP_RS14950) UPF0182 family protein [DIP0733 (VF0601) - Adherence (VFC0001)] [Corynebacterium diphtheriae NCTC 13129]
|
|
Curli fibers
|
csgC
|
0.0009136 |
10 |
VF1138
|
Adherence |
(cgsE) curli production assembly/transport protein CsgE [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131]
|
|
ChiRP
|
pilA
|
0.0011947 |
17 |
VF0609
|
Adherence |
(pilB) type IV-A pilus assembly ATPase PilB [ChiRP (VF0609) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961]
|
|
FeoAB
|
feoB
|
0.0009136 |
13 |
VF0160
|
Nutritional/Metabolic factor |
(feoB) ferrous iron transporter B [FeoAB (VF0160) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Type IV pili
|
pilC
|
0.0000703 |
1 |
VF0155
|
Adherence |
(pilC) type IV pilus assembly protein PilC [Type IV pili (VF0155) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
MisL
|
misL
|
0.0000703 |
1 |
VF0397
|
Adherence |
(misL) putative autotransporter [MisL (VF0397) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Mig-5
|
mig-5
|
0.0048493 |
67 |
VF0396
|
Antimicrobial activity/Competitive advantage |
(mig-5) putative carbonic anhydrase [Mig-5 (VF0396) - Antimicrobial activity/Competitive advantage (VFC0325)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Lsp T2SS
|
lspG
|
0.0003514 |
5 |
VF0154
|
Effector delivery system |
(lspE) general secretion pathway protein E [Lsp T2SS (VF0154) - Effector delivery system (VFC0086)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
LPS
|
bplL
|
0.0009136 |
13 |
VF0033
|
Immune modulation |
(bplL) lipopolysaccharide biosynthesis protein [LPS (VF0033) - Immune modulation (VFC0258)] [Bordetella pertussis Tohama I]
|
|
Flagella
|
fliC
|
0.0018975 |
26 |
VF0157
|
Motility |
(fliI) flagellum-specific ATP synthase FliI [Flagella (VF0157) - Motility (VFC0204)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
RatB
|
ratB
|
0.0002811 |
4 |
VF0399
|
Adherence |
(ratB) putative outer membrane protein [RatB (VF0399) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
C5a peptidase
|
scpA/scpB
|
0.0000703 |
1 |
VF0278
|
Adherence |
(scpA/scpB) streptococcal C5a peptidase [C5a peptidase (VF0278) - Adherence (VFC0001)] [Streptococcus agalactiae NEM316]
|
|
MgtC
|
mgtC
|
0.0008433 |
12 |
VF1365
|
Nutritional/Metabolic factor |
(mgtC) Salmonella virulence protein MgtC [MgtC (VF1365) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
ShdA
|
shdA
|
0.0000703 |
1 |
VF0398
|
Adherence |
(shdA) AIDA autotransporter-like protein [ShdA (VF0398) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
|
|
Hsp60
|
htpB
|
1.0463139 |
14,199 |
VF0159
|
Adherence |
(htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Hap
|
hap
|
0.0000703 |
1 |
VF0037
|
Adherence |
(hap) adhesion and penetration protein Hap [Hap (VF0037) - Adherence (VFC0001)] [Haemophilus influenzae N187]
|
|
FbpABC
|
fbpA
|
0.0001406 |
2 |
VF0272
|
Nutritional/Metabolic factor |
(fbpA) iron(III) ABC transporter, periplasmic binding protein [FbpABC (VF0272) - Nutritional/Metabolic factor (VFC0272)] [Neisseria meningitidis MC58]
|
|
PsaA
|
psaA
|
0.0000703 |
1 |
VF0151
|
Nutritional/Metabolic factor |
(psaA) manganese ABC transporter, manganese-binding adhesion liprotein [PsaA (VF0151) - Nutritional/Metabolic factor (VFC0272)] [Streptococcus pneumoniae TIGR4]
|
|
O-antigen
|
galE
|
0.0011245 |
16 |
VF0392
|
Immune modulation |
(galE) UDP-glucose 4-epimerase GalE [O-antigen (VF0392) - Immune modulation (VFC0258)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
Flagella
|
fleI/flaG
|
51.7277391 |
14,229 |
VF0273
|
Motility |
(PA1458) two-component sensor [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1]
|
|
Flagella
|
motB
|
0.0561529 |
574 |
VF0394
|
Motility |
(fliL) flagellar basal body protein FliL [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081]
|
|
AdeFGH efflux pump
|
adeG
|
1.2569401 |
14,143 |
VF0504
|
Biofilm |
(adeG) cation/multidrug efflux pump [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU]
|
|
Dot/Icm T4SS
|
dotC
|
0.0000703 |
1 |
VF0503
|
Effector delivery system |
(dotC) Type IVB secretion system protein DotC, outer membrane lipoprotein of core-transmembrane complex [Dot/Icm T4SS (VF0503) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493]
|
|
FdeC
|
fdeC
|
0.0007731 |
11 |
VF0506
|
Adherence |
(fdeC) adhesin FdeC [FdeC (VF0506) - Adherence (VFC0001)] [Escherichia coli O45:K1:H7 str. S88]
|
|
LPS
|
kdtB
|
0.0006325 |
9 |
VF0056
|
Immune modulation |
(kdtB) lipopolysaccharide core biosynthesis protein [LPS (VF0056) - Immune modulation (VFC0258)] [Helicobacter pylori 26695]
|
|
MprAB
|
mprA
|
0.0000703 |
1 |
VF0298
|
Regulation |
(mprA) two-component response regulator MrpA [MprAB (VF0298) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|
|
BapA
|
bapA
|
0.0001406 |
2 |
VF0971
|
Adherence |
|
|
Mycobactin
|
mbtH
|
0.0009839 |
14 |
VF0299
|
Nutritional/Metabolic factor |
(mbtH) putative protein MbtH [Mycobactin (VF0299) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv]
|
|
Flp pili
|
VV1_RS15610
|
0.0004217 |
6 |
VF0612
|
Adherence |
(VV1_RS15610) CpaF family protein [Flp pili (VF0612) - Adherence (VFC0001)] [Vibrio vulnificus CMCP6]
|
|
TTSS secreted effectors
|
exoY
|
3.0402699 |
14,139 |
VF0853
|
Effector delivery system |
(exoT) type III secretion system effector ExoT, ADP ribosyltransferase activity and GTPase-activating protein activity [TTSS secreted effectors (VF0853) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1]
|
|
SCI (Salmonella centrisome island)/SPI-6 T6SS
|
STM0267
|
0.0007028 |
8 |
VF0974
|
Effector delivery system |
|
|
Eps T2SS
|
epsG
|
0.0018975 |
26 |
VF0613
|
Effector delivery system |
(epsI) type II secretion system minor pseudopilin GspI [Eps T2SS (VF0613) - Effector delivery system (VFC0086)] [Vibrio cholerae O395]
|
|
LPS
|
rfbC
|
0.0014759 |
21 |
VF0171
|
Immune modulation |
(LPG_RS03775) NAD-dependent epimerase/dehydratase family protein [LPS (VF0171) - Immune modulation (VFC0258)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
Urease
|
ureG
|
2.00253 |
14,210 |
VF0050
|
Stress survival |
(ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695]
|
|
CcmC
|
ccmF
|
0.0051304 |
71 |
VF0292
|
Nutritional/Metabolic factor |
(ccmC) cytochrome c-type biogenesis protein CcmC, putative heme lyase for CcmE [CcmC (VF0292) - Nutritional/Metabolic factor (VFC0272)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
|
|
EspC
|
espC
|
0.000492 |
7 |
VF0173
|
Effector delivery system |
(espC) Type III secretion system secreted protein, serine protease [EspC (VF0173) - Effector delivery system (VFC0086)] [Escherichia coli O127:H6 str. E2348/69]
|
|
Flagella
|
tlpB
|
0.0007028 |
10 |
VF0051
|
Motility |
(cheV3) chemotaxis coupling protein CheV3 [Flagella (VF0051) - Motility (VFC0204)] [Helicobacter pylori 26695]
|
|
SigE
|
sigE
|
0.0000703 |
1 |
VF0295
|
Regulation |
(sigE) ECF RNA polymerase sigma factor SigE [SigE (VF0295) - Regulation (VFC0301)] [Mycobacterium tuberculosis H37Rv]
|