| bacA |
ARO:3002986 |
316,722 |
peptide antibiotic |
antibiotic target alteration |
undecaprenyl pyrophosphate related proteins |
| OXA-17 |
ARO:3001412 |
6 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
OXA beta-lactamase |
| CTX-M-32 |
ARO:3001894 |
6 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| dfrF |
ARO:3002867 |
1 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| msbA |
ARO:3003950 |
316,728 |
nitroimidazole antibiotic |
antibiotic efflux |
ATP-binding cassette (ABC) antibiotic efflux pump |
| dfrA5 |
ARO:3002861 |
377 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| emrK |
ARO:3000206 |
3 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| aadA23 |
ARO:3002620 |
488 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| dfrA7 |
ARO:3002862 |
2,078 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| dfrA8 |
ARO:3002863 |
174 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| aadA24 |
ARO:3002621 |
102 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| dfrA17 |
ARO:3002860 |
897 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| mphB |
ARO:3000318 |
68 |
macrolide antibiotic |
antibiotic inactivation |
macrolide phosphotransferase (MPH) |
| dfrA12 |
ARO:3002858 |
4,752 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| aadA16 |
ARO:3002616 |
671 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| aadA17 |
ARO:3002617 |
297 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| dfrA14 |
ARO:3002859 |
6,317 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| aadA22 |
ARO:3002619 |
435 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| aadA12 |
ARO:3002612 |
209 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| dfrA1 |
ARO:3002854 |
3,475 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| OXA-334 |
ARO:3001522 |
1 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
OXA beta-lactamase |
| aadA13 |
ARO:3002613 |
34 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| QnrB19 |
ARO:3002734 |
9 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| mdtE |
ARO:3000795 |
1 |
macrolide antibiotic; fluoroquinolone antibiotic; penam |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| mdtC |
ARO:3000794 |
315,823 |
aminocoumarin antibiotic |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| QnrB20 |
ARO:3002735 |
239 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| mdtB |
ARO:3000793 |
314,684 |
aminocoumarin antibiotic |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| aadA15 |
ARO:3002615 |
56 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| mphA |
ARO:3000316 |
3,449 |
macrolide antibiotic |
antibiotic inactivation |
macrolide phosphotransferase (MPH) |
| CTX-M-27 |
ARO:3001889 |
64 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
CTX-M beta-lactamase |
| OXA-10 |
ARO:3001405 |
446 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
OXA beta-lactamase |
| OXA-9 |
ARO:3001404 |
16 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
OXA beta-lactamase |
| Shigella flexneri gyrA conferring resistance to fluoroquinolones |
ARO:3003940 |
1 |
fluoroquinolone antibiotic |
antibiotic target alteration |
fluoroquinolone resistant gyrA |
| vanT gene in vanG cluster |
ARO:3002972 |
2 |
glycopeptide antibiotic |
antibiotic target alteration |
glycopeptide resistance gene cluster; vanT |
| QnrB17 |
ARO:3002732 |
16 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| H-NS |
ARO:3000676 |
31 |
macrolide antibiotic; fluoroquinolone antibiotic; cephalosporin; cephamycin; penam; tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump; resistance-nodulation-cell division (RND) antibiotic efflux pump |
| CTX-M-24 |
ARO:3001886 |
5 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| aadA11 |
ARO:3002611 |
2 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| mdtA |
ARO:3000792 |
2 |
aminocoumarin antibiotic |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| mdsC |
ARO:3000791 |
298,028 |
monobactam; carbapenem; cephalosporin; cephamycin; penam; phenicol antibiotic; penem |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| CTX-M-17 |
ARO:3001880 |
1 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| mdsB |
ARO:3000790 |
297,383 |
monobactam; carbapenem; cephalosporin; cephamycin; penam; phenicol antibiotic; penem |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| aadA5 |
ARO:3002605 |
843 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| arr-2 |
ARO:3002847 |
860 |
rifamycin antibiotic |
antibiotic inactivation |
rifampin ADP-ribosyltransferase (Arr) |
| QnrB12 |
ARO:3002726 |
2 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| arr-3 |
ARO:3002848 |
2,161 |
rifamycin antibiotic |
antibiotic inactivation |
rifampin ADP-ribosyltransferase (Arr) |
| aadA6 |
ARO:3002606 |
1 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| aadA7 |
ARO:3002607 |
1,506 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| aadA8 |
ARO:3002608 |
9 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| Salmonella enterica parC conferring resistance to fluoroquinolones |
ARO:3003939 |
1 |
fluoroquinolone antibiotic |
antibiotic target alteration |
fluoroquinolone resistant parC |
| LAP-2 |
ARO:3004826 |
319 |
cephalosporin; penam; penem |
antibiotic inactivation |
LAP beta-lactamase |
| APH(3')-IIIa |
ARO:3002647 |
2 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(3') |
| aadA8b |
ARO:3004704 |
55 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| APH(3')-Ia |
ARO:3002641 |
10,772 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(3') |
| NDM-1 |
ARO:3000589 |
21 |
carbapenem; cephalosporin; cephamycin; penam |
antibiotic inactivation |
NDM beta-lactamase |
| APH(3')-IIa |
ARO:3002644 |
926 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(3') |
| NDM-5 |
ARO:3000467 |
16 |
carbapenem; cephalosporin; cephamycin; penam |
antibiotic inactivation |
NDM beta-lactamase |
| OXA-320 |
ARO:3001793 |
1 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
OXA beta-lactamase |
| APH(3'')-Ib |
ARO:3002639 |
34,261 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(3'') |
| HERA-3 |
ARO:3004818 |
201 |
penam |
antibiotic inactivation |
HERA beta-lactamase |
| APH(2'')-IIa |
ARO:3002635 |
2 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(2'') |
| vanW gene in vanI cluster |
ARO:3003724 |
1 |
glycopeptide antibiotic |
antibiotic target alteration |
vanW; glycopeptide resistance gene cluster |
| OXA-181 |
ARO:3001784 |
2 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
OXA beta-lactamase |
| linG |
ARO:3002879 |
1,250 |
lincosamide antibiotic |
antibiotic inactivation |
lincosamide nucleotidyltransferase (LNU) |
| FosA3 |
ARO:3002872 |
2,254 |
phosphonic acid antibiotic |
antibiotic inactivation |
fosfomycin thiol transferase |
| acrB |
ARO:3000216 |
316,203 |
fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| kdpE |
ARO:3003841 |
310,773 |
aminoglycoside antibiotic |
antibiotic efflux |
kdpDE |
| QnrB38 |
ARO:3002753 |
1 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| leuO |
ARO:3003843 |
315,871 |
nucleoside antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| OXA-48 |
ARO:3001782 |
15 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
OXA beta-lactamase |
| gadW |
ARO:3003838 |
3 |
macrolide antibiotic; fluoroquinolone antibiotic; penam |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| aad(6) |
ARO:3002628 |
1 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(6) |
| Mrx |
ARO:3003839 |
3,482 |
macrolide antibiotic |
antibiotic inactivation |
macrolide phosphotransferase (MPH) |
| QnrD1 |
ARO:3002788 |
110 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| mdtM |
ARO:3001214 |
313,318 |
fluoroquinolone antibiotic; lincosamide antibiotic; nucleoside antibiotic; phenicol antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| QnrD2 |
ARO:3002789 |
13 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| Escherichia coli soxS with mutation conferring antibiotic resistance |
ARO:3003511 |
316,607 |
fluoroquinolone antibiotic; monobactam; carbapenem; cephalosporin; glycylcycline; cephamycin; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; penem; disinfecting agents and antiseptics |
antibiotic target alteration; antibiotic efflux; reduced permeability to antibiotic |
ATP-binding cassette (ABC) antibiotic efflux pump; major facilitator superfamily (MFS) antibiotic efflux pump; resistance-nodulation-cell division (RND) antibiotic efflux pump; General Bacterial Porin with reduced permeability to beta-lactams |
| tet(X4) |
ARO:3004720 |
31 |
glycylcycline; tetracycline antibiotic |
antibiotic inactivation |
tetracycline inactivation enzyme |
| OXA-392 |
ARO:3001578 |
2 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
OXA beta-lactamase |
| vanC |
ARO:3000368 |
1 |
glycopeptide antibiotic |
antibiotic target alteration |
glycopeptide resistance gene cluster; Van ligase |
| APH(6)-Id |
ARO:3002660 |
35,546 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(6) |
| QnrB69 |
ARO:3002781 |
2 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| AAC(3)-VIa |
ARO:3002540 |
2,223 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(3) |
| Escherichia coli nfsA mutations conferring resistance to nitrofurantoin |
ARO:3003751 |
24 |
nitrofuran antibiotic |
antibiotic target alteration |
antibiotic resistant nfsA |
| OXA-140 |
ARO:3001452 |
3 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
OXA beta-lactamase |
| EreA |
ARO:3000361 |
39 |
macrolide antibiotic |
antibiotic inactivation |
macrolide esterase |
| mdtG |
ARO:3001329 |
9,880 |
phosphonic acid antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| AAC(3)-IVa |
ARO:3002539 |
7,503 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(3) |
| AAC(3)-IIc |
ARO:3002535 |
58 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(3) |
| tet(31) |
ARO:3000476 |
1 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| APH(6)-Ic |
ARO:3002659 |
469 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(6) |
| ErmT |
ARO:3000595 |
4 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic; streptogramin A antibiotic; streptogramin B antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| mphE |
ARO:3003741 |
206 |
macrolide antibiotic |
antibiotic inactivation |
macrolide phosphotransferase (MPH) |
| APH(3')-VIa |
ARO:3002652 |
13 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(3') |
| Escherichia coli mdfA |
ARO:3001328 |
315,996 |
tetracycline antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| AAC(3)-Ic |
ARO:3002531 |
2 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(3) |
| MdtK |
ARO:3001327 |
306,409 |
fluoroquinolone antibiotic |
antibiotic efflux |
multidrug and toxic compound extrusion (MATE) transporter |
| SAT-2 |
ARO:3002895 |
370 |
nucleoside antibiotic |
antibiotic inactivation |
streptothricin acetyltransferase (SAT) |
| mphG |
ARO:3003742 |
14 |
macrolide antibiotic |
antibiotic inactivation |
macrolide phosphotransferase (MPH) |
| BRP(MBL) |
ARO:3001205 |
47 |
glycopeptide antibiotic |
antibiotic inactivation |
Bleomycin resistant protein |
| TolC |
ARO:3000237 |
1 |
macrolide antibiotic; fluoroquinolone antibiotic; aminoglycoside antibiotic; carbapenem; cephalosporin; glycylcycline; cephamycin; penam; tetracycline antibiotic; peptide antibiotic; aminocoumarin antibiotic; rifamycin antibiotic; phenicol antibiotic; penem; disinfecting agents and antiseptics |
antibiotic efflux |
ATP-binding cassette (ABC) antibiotic efflux pump; major facilitator superfamily (MFS) antibiotic efflux pump; resistance-nodulation-cell division (RND) antibiotic efflux pump |
| APH(4)-Ia |
ARO:3002655 |
7,365 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(4) |
| QnrB59 |
ARO:3002772 |
1 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| ANT(2'')-Ia |
ARO:3000230 |
632 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(2'') |
| AAC(3)-Ia |
ARO:3002528 |
6 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(3) |
| AAC(3)-Id |
ARO:3002529 |
720 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(3) |
| Erm(49) |
ARO:3004626 |
3 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| MCR-3.5 |
ARO:3004505 |
1 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| AAC(6')-Iy |
ARO:3002569 |
242,020 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| AAC(2')-IIa |
ARO:3004628 |
243 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(2') |
| patA |
ARO:3000024 |
1 |
fluoroquinolone antibiotic |
antibiotic efflux |
ATP-binding cassette (ABC) antibiotic efflux pump |
| catIII |
ARO:3002685 |
6 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| CMY-133 |
ARO:3003653 |
2 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| AAC(3)-IIe |
ARO:3004621 |
417 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(3) |
| QnrS11 |
ARO:3004624 |
2 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| AAC(3)-IId |
ARO:3004623 |
2,365 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(3) |
| emrA |
ARO:3000027 |
316,517 |
fluoroquinolone antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| catI |
ARO:3002683 |
3,001 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| CMY-132 |
ARO:3003652 |
450 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| catII |
ARO:3002684 |
1 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| marA |
ARO:3000263 |
316,386 |
fluoroquinolone antibiotic; monobactam; carbapenem; cephalosporin; glycylcycline; cephamycin; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; penem; disinfecting agents and antiseptics |
antibiotic efflux; reduced permeability to antibiotic |
resistance-nodulation-cell division (RND) antibiotic efflux pump; General Bacterial Porin with reduced permeability to beta-lactams |
| SHV-53 |
ARO:3001110 |
2 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
SHV beta-lactamase |
| Escherichia coli UhpT with mutation conferring resistance to fosfomycin |
ARO:3003890 |
314,435 |
phosphonic acid antibiotic |
antibiotic target alteration |
antibiotic-resistant UhpT |
| QnrVC1 |
ARO:3002799 |
10 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| AcrE |
ARO:3000499 |
15 |
fluoroquinolone antibiotic; cephalosporin; cephamycin; penam |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| SCO-1 |
ARO:3004856 |
131 |
cephalosporin; penam; penem |
antibiotic inactivation |
SCO beta-lactamase |
| Escherichia coli GlpT with mutation conferring resistance to fosfomycin |
ARO:3003889 |
315,272 |
phosphonic acid antibiotic |
antibiotic target alteration |
antibiotic-resistant GlpT |
| CTX-M-164 |
ARO:3003648 |
4 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| ErmB |
ARO:3000375 |
125 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic; streptogramin A antibiotic; streptogramin B antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| CTX-M-165 |
ARO:3003649 |
8 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| emrY |
ARO:3000254 |
1 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| catB2 |
ARO:3002675 |
2 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| KPC-2 |
ARO:3002312 |
6 |
monobactam; carbapenem; cephalosporin; penam |
antibiotic inactivation |
KPC beta-lactamase |
| catB3 |
ARO:3002676 |
1,480 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| CMY-136 |
ARO:3004854 |
92 |
cephalosporin; cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| KPC-4 |
ARO:3002314 |
1 |
monobactam; carbapenem; cephalosporin; penam |
antibiotic inactivation |
KPC beta-lactamase |
| acrD |
ARO:3000491 |
314,957 |
aminoglycoside antibiotic |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| QnrS2 |
ARO:3002791 |
521 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| QnrS4 |
ARO:3002793 |
22 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| QnrS1 |
ARO:3002790 |
4,889 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| ErmC |
ARO:3000250 |
2 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic; streptogramin A antibiotic; streptogramin B antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| EreD |
ARO:3004608 |
2 |
macrolide antibiotic |
antibiotic inactivation |
macrolide esterase |
| tet(D) |
ARO:3000168 |
527 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| Salmonella serovars parE conferring resistance to fluoroquinolones |
ARO:3003317 |
4 |
fluoroquinolone antibiotic |
antibiotic target alteration |
fluoroquinolone resistant parE |
| tet(C) |
ARO:3000167 |
1,441 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| tet(B) |
ARO:3000166 |
21,266 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| AAC(6')-32 |
ARO:3002586 |
2 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| AAC(6')-Ib' |
ARO:3003676 |
7 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| dfrI |
ARO:3004645 |
16 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| CTX-M-190 |
ARO:3005613 |
1 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| dfrA15b |
ARO:3004640 |
19 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| mdtP |
ARO:3003550 |
1 |
nucleoside antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| AAC(6')-Ib11 |
ARO:3002582 |
2 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| tet(A) |
ARO:3000165 |
38,005 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| AAC(6')-Ib9 |
ARO:3002580 |
363 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| AAC(6')-Ib10 |
ARO:3002581 |
182 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| CTX-M-186 |
ARO:3005609 |
6 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| AAC(6')-Ib8 |
ARO:3002579 |
35 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| qnrE2 |
ARO:3004637 |
1 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| Morganella morganii gyrB conferring resistance to fluoroquinolones |
ARO:3003306 |
56 |
fluoroquinolone antibiotic |
antibiotic target alteration |
fluoroquinolone resistant gyrB |
| mdtN |
ARO:3003548 |
30 |
nucleoside antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| qnrE1 |
ARO:3004636 |
30 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| TEM-141 |
ARO:3001004 |
8 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| Salmonella serovars gyrB conferring resistance to fluoroquinolones |
ARO:3003307 |
151 |
fluoroquinolone antibiotic |
antibiotic target alteration |
fluoroquinolone resistant gyrB |
| mdtO |
ARO:3003549 |
1 |
nucleoside antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| IMP-27 |
ARO:3002218 |
3 |
carbapenem; cephalosporin; cephamycin; penam; penem |
antibiotic inactivation |
IMP beta-lactamase |
| Escherichia coli parC conferring resistance to fluoroquinolones |
ARO:3003308 |
2,007 |
fluoroquinolone antibiotic |
antibiotic target alteration |
fluoroquinolone resistant parC |
| cmlA6 |
ARO:3002696 |
117 |
phenicol antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| MCR-3.2 |
ARO:3004511 |
6 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| AAC(6')-Il |
ARO:3004635 |
18 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| AAC(6')-Ib7 |
ARO:3002578 |
1 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| AAC(6')-Iaa |
ARO:3002571 |
73,377 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| cmlA1 |
ARO:3002693 |
3,298 |
phenicol antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| cmlA4 |
ARO:3002694 |
26 |
phenicol antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| cmlA5 |
ARO:3002695 |
670 |
phenicol antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| AAC(6')-Im |
ARO:3004629 |
2 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| KLUC-2 |
ARO:3006928 |
1 |
cephalosporin |
antibiotic inactivation |
KLUC beta-lactamase |
| dfrB5 |
ARO:3004549 |
3 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| TEM-171 |
ARO:3001037 |
24 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| CTX-M-151 |
ARO:3002008 |
1 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| OXA-4 |
ARO:3001399 |
7 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
OXA beta-lactamase |
| TEM-169 |
ARO:3001035 |
3 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| ugd |
ARO:3003577 |
316,307 |
peptide antibiotic |
antibiotic target alteration |
pmr phosphoethanolamine transferase |
| PmrF |
ARO:3003578 |
315,634 |
peptide antibiotic |
antibiotic target alteration |
pmr phosphoethanolamine transferase |
| CTX-M-207 |
ARO:3005630 |
1 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| CARB-3 |
ARO:3002242 |
4,184 |
penam |
antibiotic inactivation |
CARB beta-lactamase |
| FosA4 |
ARO:3003210 |
58 |
phosphonic acid antibiotic |
antibiotic inactivation |
fosfomycin thiol transferase |
| tet(Y) |
ARO:3000182 |
3 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| TEM-215 |
ARO:3001392 |
25 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-214 |
ARO:3001391 |
139 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| CARB-4 |
ARO:3002243 |
3 |
penam |
antibiotic inactivation |
CARB beta-lactamase |
| CMY-111 |
ARO:3002122 |
1 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| CTX-M-208 |
ARO:3005631 |
1 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| OXA-2 |
ARO:3001397 |
32 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
OXA beta-lactamase |
| TEM-168 |
ARO:3001034 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| tet(M) |
ARO:3000186 |
2,079 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| OXA-1 |
ARO:3001396 |
1,708 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
OXA beta-lactamase |
| catB11 |
ARO:3004660 |
6 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| TEM-166 |
ARO:3001032 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| NDM-9 |
ARO:3002359 |
12 |
carbapenem; cephalosporin; cephamycin; penam |
antibiotic inactivation |
NDM beta-lactamase |
| tet(K) |
ARO:3000178 |
2 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| TEM-159 |
ARO:3001025 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| tet(J) |
ARO:3000177 |
2 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| TEM-210 |
ARO:3001387 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| fosA5 |
ARO:3003209 |
3 |
fluoroquinolone antibiotic; aminoglycoside antibiotic; phosphonic acid antibiotic |
antibiotic inactivation |
fosfomycin thiol transferase |
| AAC(6')-Ie-APH(2'')-Ia bifunctional protein |
ARO:3002597 |
1 |
aminoglycoside antibiotic |
antibiotic inactivation |
aminoglycoside bifunctional resistance protein |
| LEN-14 |
ARO:3002477 |
2 |
penam; penem |
antibiotic inactivation |
LEN beta-lactamase |
| CTX-M-199 |
ARO:3005622 |
3 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| TEM-163 |
ARO:3001029 |
33 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| catA4 |
ARO:3004657 |
2 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| NDM-7 |
ARO:3002357 |
1 |
carbapenem; cephalosporin; cephamycin; penam |
antibiotic inactivation |
NDM beta-lactamase |
| catII from Escherichia coli K-12 |
ARO:3004656 |
793 |
phenicol antibiotic |
antibiotic inactivation |
chloramphenicol acetyltransferase (CAT) |
| MCR-1.1 |
ARO:3003689 |
462 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| lin |
ARO:3004651 |
1 |
lincosamide antibiotic |
antibiotic inactivation |
lincosamide nucleotidyltransferase (LNU) |
| cfrA |
ARO:3003441 |
8 |
lincosamide antibiotic; streptogramin antibiotic; streptogramin A antibiotic; oxazolidinone antibiotic; phenicol antibiotic; pleuromutilin antibiotic |
antibiotic target alteration |
Cfr 23S ribosomal RNA methyltransferase |
| AAC(6')-IIa |
ARO:3002594 |
5 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| AAC(6')-Ian |
ARO:3003200 |
5 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| CTX-M-198 |
ARO:3005621 |
1 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| AAC(6')-IIc |
ARO:3002596 |
387 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6') |
| TEM-209 |
ARO:3001386 |
84 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| tet(H) |
ARO:3000175 |
3 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| TEM-207 |
ARO:3001384 |
2 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-206 |
ARO:3001383 |
434 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| tet(E) |
ARO:3000173 |
4 |
tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| SHV-1 |
ARO:3001059 |
2 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
SHV beta-lactamase |
| Haemophilus influenzae PBP3 conferring resistance to beta-lactam antibiotics |
ARO:3004446 |
316,667 |
cephalosporin; cephamycin; penam |
antibiotic target alteration |
Penicillin-binding protein mutations conferring resistance to beta-lactam antibiotics |
| DHA-15 |
ARO:3002146 |
7 |
cephalosporin; cephamycin |
antibiotic inactivation |
DHA beta-lactamase |
| SFO-1 |
ARO:3006986 |
2 |
carbapenem |
antibiotic inactivation |
SFO beta-lactamase |
| tetR |
ARO:3003479 |
21,344 |
tetracycline antibiotic |
antibiotic target alteration; antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| CMY-16 |
ARO:3002027 |
3 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| HERA-1 |
ARO:3004448 |
18 |
penam |
antibiotic inactivation |
HERA beta-lactamase |
| CMY-17 |
ARO:3002028 |
4 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| MCR-9.1 |
ARO:3004684 |
1,197 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| tet(W/N/W) |
ARO:3004442 |
2 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| TEM-191 |
ARO:3001051 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-190 |
ARO:3001050 |
2 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| MCR-1.5 |
ARO:3004685 |
1 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| DHA-9 |
ARO:3002140 |
1 |
cephalosporin; cephamycin |
antibiotic inactivation |
DHA beta-lactamase |
| mef(B) |
ARO:3003107 |
100 |
macrolide antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| CTX-M-226 |
ARO:3005649 |
2 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| msrE |
ARO:3003109 |
204 |
macrolide antibiotic; streptogramin antibiotic |
antibiotic target protection |
msr-type ABC-F protein |
| VEB-8 |
ARO:3002377 |
4 |
monobactam; cephalosporin |
antibiotic inactivation |
VEB beta-lactamase |
| dfrA32 |
ARO:3004555 |
25 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| CMY-4 |
ARO:3002015 |
17 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| Erm(42) |
ARO:3003106 |
59 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| rmtE |
ARO:3004678 |
49 |
aminoglycoside antibiotic |
antibiotic target alteration |
16S rRNA methyltransferase (G1405) |
| CMY-6 |
ARO:3002017 |
4 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| TEM-176 |
ARO:3001041 |
70 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| tet(W) |
ARO:3000194 |
3 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| CTX-M-153 |
ARO:3002010 |
1 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| DHA-1 |
ARO:3002132 |
187 |
cephalosporin; cephamycin |
antibiotic inactivation |
DHA beta-lactamase |
| VEB-5 |
ARO:3002375 |
1 |
monobactam; cephalosporin |
antibiotic inactivation |
VEB beta-lactamase |
| aphA15 |
ARO:3004675 |
1 |
aminoglycoside antibiotic |
antibiotic inactivation |
APH(3') |
| CMY-2 |
ARO:3002013 |
8,893 |
carbapenem; cephalosporin; cephamycin; penam |
antibiotic inactivation |
CMY beta-lactamase |
| tet(Q) |
ARO:3000191 |
3 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| TEM-183 |
ARO:3001045 |
4 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-181 |
ARO:3001044 |
5 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| VEB-1 |
ARO:3002370 |
1 |
monobactam; cephalosporin |
antibiotic inactivation |
VEB beta-lactamase |
| dfrA27 |
ARO:3004550 |
683 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| tet(32) |
ARO:3000196 |
4 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| emrB |
ARO:3000074 |
315,939 |
fluoroquinolone antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| tet(O) |
ARO:3000190 |
191 |
tetracycline antibiotic |
antibiotic target protection |
tetracycline-resistant ribosomal protection protein |
| dfrA23 |
ARO:3003019 |
114 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| Escherichia coli AcrAB-TolC with MarR mutations conferring resistance to ciprofloxacin and tetracycline |
ARO:3003378 |
316,448 |
fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics |
antibiotic target alteration; antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| dfrA19 |
ARO:3003015 |
354 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| Salmonella enterica ramR mutants |
ARO:3003379 |
181 |
fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics |
antibiotic target alteration; antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| dfrA21 |
ARO:3003017 |
27 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| dfrA10 |
ARO:3003011 |
25 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| CMY-32 |
ARO:3002043 |
1 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| dfrA15 |
ARO:3003013 |
212 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| QepA2 |
ARO:3004103 |
35 |
fluoroquinolone antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| SHV-12 |
ARO:3001071 |
431 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
SHV beta-lactamase |
| Klebsiella pneumoniae KpnE |
ARO:3004580 |
316,522 |
macrolide antibiotic; aminoglycoside antibiotic; cephalosporin; tetracycline antibiotic; peptide antibiotic; rifamycin antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
small multidrug resistance (SMR) antibiotic efflux pump |
| Klebsiella pneumoniae KpnF |
ARO:3004583 |
315,032 |
macrolide antibiotic; aminoglycoside antibiotic; cephalosporin; tetracycline antibiotic; peptide antibiotic; rifamycin antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
small multidrug resistance (SMR) antibiotic efflux pump |
| CMY-30 |
ARO:3002041 |
1 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| EC-5 |
ARO:3006880 |
2 |
cephalosporin |
antibiotic inactivation |
EC beta-lactamase |
| SHV-11 |
ARO:3001070 |
1 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
SHV beta-lactamase |
| Escherichia coli EF-Tu mutants conferring resistance to Pulvomycin |
ARO:3003369 |
107,363 |
elfamycin antibiotic |
antibiotic target alteration |
elfamycin resistant EF-Tu |
| FOX-5 |
ARO:3002159 |
3 |
cephalosporin; cephamycin |
antibiotic inactivation |
FOX beta-lactamase |
| MCR-5.1 |
ARO:3004332 |
11 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| Salmonella enterica gyrA with mutation conferring resistance to triclosan |
ARO:3004334 |
10,343 |
disinfecting agents and antiseptics |
antibiotic target alteration |
triclosan resistant gyrA |
| SHV-2A |
ARO:3001061 |
20 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
SHV beta-lactamase |
| CfxA2 |
ARO:3003002 |
1 |
cephamycin |
antibiotic inactivation |
CfxA beta-lactamase |
| SHV-2 |
ARO:3001060 |
4 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
SHV beta-lactamase |
| SHV-7 |
ARO:3001066 |
16 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
SHV beta-lactamase |
| VIM-1 |
ARO:3002271 |
9 |
carbapenem; cephalosporin; cephamycin; penam; penem |
antibiotic inactivation |
VIM beta-lactamase |
| VIM-2 |
ARO:3002272 |
1 |
carbapenem; cephalosporin; cephamycin; penam; penem |
antibiotic inactivation |
VIM beta-lactamase |
| SHV-5 |
ARO:3001064 |
10 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
SHV beta-lactamase |
| CMY-59 |
ARO:3002069 |
31 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| sul4 |
ARO:3004361 |
4 |
sulfonamide antibiotic |
antibiotic target replacement |
sulfonamide resistant sul |
| dfrB3 |
ARO:3003022 |
5 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| CMY-43 |
ARO:3002054 |
1 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| Escherichia coli folP with mutation conferring resistance to sulfonamides |
ARO:3003386 |
151 |
sulfonamide antibiotic |
antibiotic target alteration |
sulfonamide resistant dihydropteroate synthase folP |
| FosA6 |
ARO:3004111 |
9 |
phosphonic acid antibiotic |
antibiotic inactivation |
fosfomycin thiol transferase |
| Klebsiella pneumoniae KpnH |
ARO:3004597 |
647 |
macrolide antibiotic; fluoroquinolone antibiotic; aminoglycoside antibiotic; carbapenem; cephalosporin; penam; peptide antibiotic; penem |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| FosA7 |
ARO:3004113 |
15,669 |
phosphonic acid antibiotic |
antibiotic inactivation |
fosfomycin thiol transferase |
| Escherichia coli soxR with mutation conferring antibiotic resistance |
ARO:3003381 |
312,380 |
fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics |
antibiotic target alteration; antibiotic efflux |
ATP-binding cassette (ABC) antibiotic efflux pump; major facilitator superfamily (MFS) antibiotic efflux pump; resistance-nodulation-cell division (RND) antibiotic efflux pump |
| SHV-30 |
ARO:3001088 |
2 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
SHV beta-lactamase |
| dfrA25 |
ARO:3003020 |
21 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| CMY-42 |
ARO:3002053 |
2 |
cephalosporin; cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| AAC(6')-Ib-cr6 |
ARO:3005116 |
2,181 |
fluoroquinolone antibiotic; aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6'); AAC(6')-Ib-cr |
| smeD |
ARO:3003055 |
1 |
macrolide antibiotic; fluoroquinolone antibiotic; tetracycline antibiotic; phenicol antibiotic |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| smeE |
ARO:3003056 |
9 |
macrolide antibiotic; fluoroquinolone antibiotic; tetracycline antibiotic; phenicol antibiotic |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| AAC(6')-Ib-cr3 |
ARO:3005112 |
4 |
fluoroquinolone antibiotic; aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6'); AAC(6')-Ib-cr |
| AAC(6')-Ib-cr5 |
ARO:3005115 |
4 |
fluoroquinolone antibiotic; aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6'); AAC(6')-Ib-cr |
| AAC(6')-Ib-cr4 |
ARO:3005114 |
18 |
fluoroquinolone antibiotic; aminoglycoside antibiotic |
antibiotic inactivation |
AAC(6'); AAC(6')-Ib-cr |
| smeA |
ARO:3003051 |
8 |
aminoglycoside antibiotic; cephalosporin; cephamycin; penam |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| Escherichia coli gyrA conferring resistance to fluoroquinolones |
ARO:3003294 |
37 |
fluoroquinolone antibiotic |
antibiotic target alteration |
fluoroquinolone resistant gyrA |
| DfrB9 |
ARO:3005350 |
5 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| DfrA36 |
ARO:3005348 |
4 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| QepA4 |
ARO:3004379 |
38 |
fluoroquinolone antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| DfrA37 |
ARO:3005347 |
9 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| MCR-3.1 |
ARO:3004139 |
68 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| Escherichia coli rpoB mutants conferring resistance to rifampicin |
ARO:3003288 |
33 |
rifamycin antibiotic |
antibiotic target alteration; antibiotic target replacement |
rifamycin-resistant beta-subunit of RNA polymerase (rpoB) |
| DfrA34 |
ARO:3005346 |
254 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| CARB-53 |
ARO:3005587 |
15 |
penam |
antibiotic inactivation |
CARB beta-lactamase |
| dfrB4 |
ARO:3004498 |
3 |
diaminopyrimidine antibiotic |
antibiotic target replacement |
trimethoprim resistant dihydrofolate reductase dfr |
| CMY-58 |
ARO:3002072 |
1 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| CMY-61 |
ARO:3002074 |
1 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| TEM-52 |
ARO:3000921 |
14 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| ACC-1a |
ARO:3006228 |
9 |
monobactam; cephalosporin; penam |
antibiotic inactivation |
ACC beta-lactamase |
| DHA-27 |
ARO:3006468 |
1 |
cephalosporin; cephamycin |
antibiotic inactivation |
DHA beta-lactamase |
| Escherichia coli fabI mutations conferring resistance to isoniazid and triclosan |
ARO:3004045 |
4 |
disinfecting agents and antiseptics; isoniazid-like antibiotic |
antibiotic target alteration |
antibiotic resistant fabI |
| CMY-174 |
ARO:3006463 |
36 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| qacEdelta1 |
ARO:3005010 |
26,409 |
disinfecting agents and antiseptics |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| Escherichia coli acrA |
ARO:3004043 |
316,707 |
fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| aadA25 |
ARO:3003197 |
9 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| mphF |
ARO:3003071 |
1 |
macrolide antibiotic |
antibiotic inactivation |
macrolide phosphotransferase (MPH) |
| Escherichia coli emrE |
ARO:3004039 |
8 |
macrolide antibiotic |
antibiotic efflux |
small multidrug resistance (SMR) antibiotic efflux pump |
| TEM-40 |
ARO:3000910 |
5 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| qacE |
ARO:3005009 |
3 |
disinfecting agents and antiseptics |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| CMY-159 |
ARO:3006458 |
2 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| smeR |
ARO:3003066 |
8 |
aminoglycoside antibiotic; cephalosporin; cephamycin; penam |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| smeS |
ARO:3003067 |
8 |
aminoglycoside antibiotic; cephalosporin; cephamycin; penam |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| QnrB76 |
ARO:3003188 |
20 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| QnrB77 |
ARO:3003189 |
18 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| VEB-17 |
ARO:3006213 |
1 |
monobactam; cephalosporin |
antibiotic inactivation |
VEB beta-lactamase |
| Klebsiella pneumoniae PBP3 mutants conferring resistance to ceftazidime-avibactam |
ARO:3007421 |
1 |
cephalosporin; cephamycin; penam |
antibiotic target alteration |
Penicillin-binding protein mutations conferring resistance to beta-lactam antibiotics |
| TEM-33 |
ARO:3000903 |
2 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-32 |
ARO:3000902 |
26 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-31 |
ARO:3000901 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-30 |
ARO:3000900 |
24 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-36 |
ARO:3000906 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-35 |
ARO:3000905 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-34 |
ARO:3000904 |
3 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| BLMT |
ARO:3005036 |
13 |
glycopeptide antibiotic |
antibiotic inactivation |
Bleomycin resistant protein |
| TEM-244 |
ARO:3007453 |
806 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-245 |
ARO:3007454 |
40 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-243 |
ARO:3005273 |
643 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-247 |
ARO:3007451 |
19 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-70 |
ARO:3000936 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-71 |
ARO:3000937 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| FosL1 |
ARO:3005024 |
13 |
phosphonic acid antibiotic |
antibiotic inactivation |
fosfomycin thiol transferase |
| TEM-238 |
ARO:3005269 |
14 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-234 |
ARO:3005265 |
10 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| Escherichia coli ampC beta-lactamase |
ARO:3004290 |
4 |
cephalosporin; penam |
antibiotic inactivation |
ampC-type beta-lactamase |
| TEM-229 |
ARO:3005260 |
2 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-57 |
ARO:3000926 |
341 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| OXA-129 |
ARO:3001811 |
4 |
carbapenem; cephalosporin; penam |
antibiotic inactivation |
OXA beta-lactamase |
| TEM-95 |
ARO:3000962 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| ANT(3'')-IIa |
ARO:3004089 |
17,433 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| MCR-1.18 |
ARO:3007233 |
4 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| ArnT |
ARO:3005053 |
316,748 |
peptide antibiotic |
antibiotic target alteration |
pmr phosphoethanolamine transferase |
| lnuG |
ARO:3004085 |
199 |
lincosamide antibiotic |
antibiotic inactivation |
lincosamide nucleotidyltransferase (LNU) |
| MCR-4.6 |
ARO:3007231 |
4 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| tet(X6) |
ARO:3005056 |
1 |
tetracycline antibiotic |
antibiotic inactivation |
tetracycline inactivation enzyme |
| MCR-1.34 |
ARO:3007230 |
1 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| CTX-M-64 |
ARO:3001925 |
34 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| CTX-M-65 |
ARO:3001926 |
4,114 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| evgS |
ARO:3000833 |
1 |
macrolide antibiotic; fluoroquinolone antibiotic; penam; tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump; resistance-nodulation-cell division (RND) antibiotic efflux pump |
| evgA |
ARO:3000832 |
3 |
macrolide antibiotic; fluoroquinolone antibiotic; penam; tetracycline antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump; resistance-nodulation-cell division (RND) antibiotic efflux pump |
| cpxA |
ARO:3000830 |
316,554 |
aminoglycoside antibiotic; aminocoumarin antibiotic |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| TEM-84 |
ARO:3000951 |
6 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| cmlA9 |
ARO:3005043 |
27 |
phenicol antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| FosA7.5 |
ARO:3005162 |
18 |
phosphonic acid antibiotic |
antibiotic inactivation |
fosfomycin thiol transferase |
| MCR-1.2 |
ARO:3004194 |
1 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| sdiA |
ARO:3000826 |
315,584 |
fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| CTX-M-55 |
ARO:3001917 |
1,093 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| ramA |
ARO:3000823 |
3 |
fluoroquinolone antibiotic; monobactam; carbapenem; cephalosporin; glycylcycline; cephamycin; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; penem; disinfecting agents and antiseptics |
antibiotic efflux; reduced permeability to antibiotic |
resistance-nodulation-cell division (RND) antibiotic efflux pump; General Bacterial Porin with reduced permeability to beta-lactams |
| baeS |
ARO:3000829 |
1 |
aminoglycoside antibiotic; aminocoumarin antibiotic |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| baeR |
ARO:3000828 |
316,612 |
aminoglycoside antibiotic; aminocoumarin antibiotic |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| TEM-120 |
ARO:3000982 |
5 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| rmtB |
ARO:3000860 |
175 |
aminoglycoside antibiotic |
antibiotic target alteration |
16S rRNA methyltransferase (G1405) |
| QnrVC4 |
ARO:3002801 |
9 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| QnrVC5 |
ARO:3002802 |
1 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| CTX-M-90 |
ARO:3001950 |
2 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| TEM-122 |
ARO:3000984 |
17 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| PC1 beta-lactamase (blaZ) |
ARO:3000621 |
1 |
penam |
antibiotic inactivation |
BlaZ beta-lactamase |
| qacG |
ARO:3007015 |
2,343 |
disinfecting agents and antiseptics |
antibiotic efflux |
small multidrug resistance (SMR) antibiotic efflux pump |
| qacJ |
ARO:3007014 |
723 |
disinfecting agents and antiseptics |
antibiotic efflux |
small multidrug resistance (SMR) antibiotic efflux pump |
| mdeA |
ARO:3007011 |
1 |
fluoroquinolone antibiotic; aminoglycoside antibiotic; penam; tetracycline antibiotic; disinfecting agents and antiseptics |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| CMY-157 |
ARO:3005198 |
3 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| CMY-142 |
ARO:3005195 |
1 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| FosI |
ARO:3007370 |
1 |
phosphonic acid antibiotic |
antibiotic inactivation |
fosfomycin thiol transferase |
| FosA8 |
ARO:3007371 |
5,895 |
phosphonic acid antibiotic |
antibiotic inactivation |
fosfomycin thiol transferase |
| TEM-116 |
ARO:3000979 |
97 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| armA |
ARO:3000858 |
216 |
aminoglycoside antibiotic |
antibiotic target alteration |
16S rRNA methyltransferase (G1405) |
| vanR gene in vanA cluster |
ARO:3002919 |
1 |
glycopeptide antibiotic |
antibiotic target alteration |
glycopeptide resistance gene cluster; vanR |
| rsmA |
ARO:3005069 |
316,842 |
fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| ROB-11 |
ARO:3007125 |
5 |
cephalosporin; penam |
antibiotic inactivation |
ROB beta-lactamase |
| ACT-84 |
ARO:3006278 |
1 |
carbapenem; cephalosporin; cephamycin; penam |
antibiotic inactivation |
ACT beta-lactamase |
| CMY-165 |
ARO:3005188 |
13 |
cephamycin |
antibiotic inactivation |
CMY beta-lactamase |
| MCR-1.19 |
ARO:3007240 |
2 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| TEM-105 |
ARO:3000968 |
3 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-104 |
ARO:3000967 |
9 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| vanG |
ARO:3002909 |
315,116 |
glycopeptide antibiotic |
antibiotic target alteration |
glycopeptide resistance gene cluster; Van ligase |
| TEM-12 |
ARO:3000884 |
3 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| vanH gene in vanA cluster |
ARO:3002942 |
3 |
glycopeptide antibiotic |
antibiotic target alteration |
vanH; glycopeptide resistance gene cluster |
| CTX-M-115 |
ARO:3001975 |
9 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| TEM-10 |
ARO:3000882 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| cmx |
ARO:3002703 |
2 |
phenicol antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| qacL |
ARO:3005098 |
3,990 |
disinfecting agents and antiseptics |
antibiotic efflux |
small multidrug resistance (SMR) antibiotic efflux pump |
| MCR-3.39 |
ARO:3007271 |
1 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| CRP |
ARO:3000518 |
316,484 |
macrolide antibiotic; fluoroquinolone antibiotic; penam |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| emrR |
ARO:3000516 |
316,713 |
fluoroquinolone antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| TEM-135 |
ARO:3000999 |
465 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-1 |
ARO:3000873 |
25,387 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| CTX-M-104 |
ARO:3001963 |
10 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| CTX-M-101 |
ARO:3001960 |
1 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| TEM-2 |
ARO:3000874 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-131 |
ARO:3000995 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-128 |
ARO:3000990 |
2 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| MCR-3.40 |
ARO:3007264 |
4 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| MCR-3.24 |
ARO:3007265 |
4 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| MCR-3.21 |
ARO:3007262 |
3 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| AAC(3)-IIg |
ARO:3005085 |
384 |
aminoglycoside antibiotic |
antibiotic inactivation |
AAC(3) |
| golS |
ARO:3000504 |
299,581 |
monobactam; carbapenem; cephalosporin; cephamycin; penam; phenicol antibiotic; penem |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| FosA2 |
ARO:3002804 |
95 |
phosphonic acid antibiotic |
antibiotic inactivation |
fosfomycin thiol transferase |
| CTX-M-98 |
ARO:3001957 |
1 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| CTX-M-99 |
ARO:3001958 |
1 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| gadX |
ARO:3000508 |
6 |
macrolide antibiotic; fluoroquinolone antibiotic; penam |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| aadA2 |
ARO:3002602 |
7,811 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| CTX-M-10 |
ARO:3001873 |
1 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| norB |
ARO:3000421 |
1 |
fluoroquinolone antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| aadA3 |
ARO:3002603 |
4,113 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| QnrB10 |
ARO:3002724 |
6,198 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| CTX-M-9 |
ARO:3001872 |
59 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| CTX-M-8 |
ARO:3001871 |
78 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| aadA4 |
ARO:3002604 |
28 |
aminoglycoside antibiotic |
antibiotic inactivation |
ANT(3'') |
| CTX-M-15 |
ARO:3001878 |
572 |
cephalosporin; penam |
antibiotic inactivation |
CTX-M beta-lactamase |
| mdsA |
ARO:3000789 |
297,917 |
monobactam; carbapenem; cephalosporin; cephamycin; penam; phenicol antibiotic; penem |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| vanY gene in vanM cluster |
ARO:3002961 |
11 |
glycopeptide antibiotic |
antibiotic target alteration |
vanY; glycopeptide resistance gene cluster |
| CTX-M-14 |
ARO:3001877 |
528 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| QnrB6 |
ARO:3002720 |
468 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| CTX-M-137 |
ARO:3001994 |
1 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| vanZ gene in vanA cluster |
ARO:3002962 |
1 |
glycopeptide antibiotic |
antibiotic target alteration |
vanZ; glycopeptide resistance gene cluster |
| QnrB7 |
ARO:3002721 |
46 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| CTX-M-12 |
ARO:3001875 |
3 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| QnrB5 |
ARO:3002719 |
2,658 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| CTX-M-130 |
ARO:3001989 |
19 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| Salmonella enterica gyrA conferring resistance to fluoroquinolones |
ARO:3003926 |
24,897 |
fluoroquinolone antibiotic |
antibiotic target alteration |
fluoroquinolone resistant gyrA |
| vanY gene in vanF cluster |
ARO:3002958 |
2 |
glycopeptide antibiotic |
antibiotic target alteration |
vanY; glycopeptide resistance gene cluster |
| lnuC |
ARO:3002837 |
3 |
lincosamide antibiotic |
antibiotic inactivation |
lincosamide nucleotidyltransferase (LNU) |
| Escherichia coli AcrAB-TolC with AcrR mutation conferring resistance to ciprofloxacin, tetracycline, and ceftazidime |
ARO:3003807 |
315,980 |
fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics |
antibiotic target alteration; antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| QnrB4 |
ARO:3002718 |
192 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| lnuF |
ARO:3002839 |
35 |
lincosamide antibiotic |
antibiotic inactivation |
lincosamide nucleotidyltransferase (LNU) |
| sul1 |
ARO:3000410 |
25,848 |
sulfonamide antibiotic |
antibiotic target replacement |
sulfonamide resistant sul |
| oqxA |
ARO:3003922 |
1,473 |
fluoroquinolone antibiotic; glycylcycline; tetracycline antibiotic; diaminopyrimidine antibiotic; nitrofuran antibiotic |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| oqxB |
ARO:3003923 |
1,459 |
fluoroquinolone antibiotic; glycylcycline; tetracycline antibiotic; diaminopyrimidine antibiotic; nitrofuran antibiotic |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| vanY gene in vanA cluster |
ARO:3002955 |
3 |
glycopeptide antibiotic |
antibiotic target alteration |
vanY; glycopeptide resistance gene cluster |
| QnrB1 |
ARO:3002714 |
66 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| lnuA |
ARO:3002835 |
12 |
lincosamide antibiotic |
antibiotic inactivation |
lincosamide nucleotidyltransferase (LNU) |
| vanY gene in vanB cluster |
ARO:3002956 |
1 |
glycopeptide antibiotic |
antibiotic target alteration |
vanY; glycopeptide resistance gene cluster |
| TEM-29 |
ARO:3000899 |
2 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| adeF |
ARO:3000777 |
1,884 |
fluoroquinolone antibiotic; tetracycline antibiotic |
antibiotic efflux |
resistance-nodulation-cell division (RND) antibiotic efflux pump |
| CTX-M-123 |
ARO:3001982 |
67 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| CTX-M-3 |
ARO:3001866 |
27 |
cephalosporin; cephamycin; penam |
antibiotic inactivation |
CTX-M beta-lactamase |
| sul3 |
ARO:3000413 |
4,495 |
sulfonamide antibiotic |
antibiotic target replacement |
sulfonamide resistant sul |
| CTX-M-2 |
ARO:3001865 |
55 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| CTX-M-1 |
ARO:3001864 |
204 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| sul2 |
ARO:3000412 |
30,798 |
sulfonamide antibiotic |
antibiotic target replacement |
sulfonamide resistant sul |
| CTX-M-125 |
ARO:3001984 |
7 |
cephalosporin |
antibiotic inactivation |
CTX-M beta-lactamase |
| TEM-26 |
ARO:3000896 |
2 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-20 |
ARO:3000891 |
2 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| TEM-19 |
ARO:3000890 |
1 |
monobactam; cephalosporin; penam; penem |
antibiotic inactivation |
TEM beta-lactamase |
| mefF |
ARO:3007044 |
1 |
macrolide antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| msr(G) |
ARO:3007042 |
1 |
macrolide antibiotic; streptogramin antibiotic |
antibiotic target protection |
msr-type ABC-F protein |
| Erm(52) |
ARO:3007041 |
4 |
macrolide antibiotic; lincosamide antibiotic; streptogramin antibiotic |
antibiotic target alteration |
Erm 23S ribosomal RNA methyltransferase |
| MCR-1.26 |
ARO:3007280 |
9 |
peptide antibiotic |
antibiotic target alteration |
MCR phosphoethanolamine transferase |
| QnrA3 |
ARO:3002709 |
1 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| fexA |
ARO:3002704 |
1 |
phenicol antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| floR |
ARO:3002705 |
20,277 |
phenicol antibiotic |
antibiotic efflux |
major facilitator superfamily (MFS) antibiotic efflux pump |
| EreA2 |
ARO:3002826 |
389 |
macrolide antibiotic |
antibiotic inactivation |
macrolide esterase |
| QnrA1 |
ARO:3002707 |
1,304 |
fluoroquinolone antibiotic |
antibiotic target protection |
quinolone resistance protein (qnr) |
| vanX gene in vanA cluster |
ARO:3002949 |
2 |
glycopeptide antibiotic |
antibiotic target alteration |
vanX; glycopeptide resistance gene cluster |