IBD Research Resource Center

Target ID:	dt622
CID:	447043
Compound Name:	Azithromycin
Gene ID:	59
Gene Name:	ACTA2
Species:	Homo sapiens (human)
PubMed IDs:	36581200
Action:	Azithromycin inhibits the reaction [transforming growth factor beta1 results in increased expression of ACTA2 protein]

Knowledge Graph

Target ID	CID	Compound Name	Gene ID	Gene Name	Species	Action
dt1130	54670067	Ascorbic Acid	59	ACTA2	Homo sapiens (human)	[mercaptoethanol co-treated with ascorbic acid] results in increased expression of ACTA2 protein	Details
dt323	4740	Pentoxifylline	59	ACTA2	Homo sapiens (human)	Pentoxifylline promotes the reaction [carbon tetrachloride results in increased expression of ACTA2 mrna]	Details
dt324	4740	Pentoxifylline	59	ACTA2	Rattus norvegicus (Norway rat)	Pentoxifylline results in decreased expression of ACTA2 protein	Details
dt717	5280483	Vitamin K	59	ACTA2	Rattus norvegicus (Norway rat)	[warfarin co-treated with vitamin K co-treated with quercetin] results in increased expression of ACTA2 mRNA	Details
dt726	5280492	Leukotriene B4	59	ACTA2	Homo sapiens (human)	Leukotriene B4 results in increased expression of ACTA2 protein	Details
dt727	5280492	Leukotriene B4	59	ACTA2	Mus musculus (house mouse)	Leukotriene B4 results in increased expression of ACTA2 mRNA	Details
dt757	5281233	Crocin	59	ACTA2	Rattus norvegicus (Norway rat)	Crocin inhibits the reaction [carbon tetrachloride results in increased expression of ACTA2 protein]\|crocin inhibits the reaction [carbon tetrachloride results in increased expression of ACTA2 mrna]	Details

Drug ID	Drug Name	Type	DrugBank ID	Targets	Category	Latest Progress
Drug73	Azithromycin	Chemical drug	--	--	--	Under clinical trials	Details

Compound ID	Source ID	Source Type	Compound Name	Molecular Weight	Molecular Formula	Molecular Species
No data available

Disease ID	Disease Name	Definition	Mechanism
No data available

Strategy ID	Therapy Strategy	Synonyms	Related Drugs	Mechanism
No data available