| Target ID: | dt730 |
|---|---|
| CID: | 5280492 |
| Compound Name: | Leukotriene B4 |
| Gene ID: | 240 |
| Gene Name: | ALOX5 |
| Species: | Homo sapiens (human) |
| PubMed IDs: | 15501964 |
| Action: | ALOX5 protein promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased abundance of leukotriene b4]|zileuton inhibits the reaction [ALOX5 protein promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased abundanc |
Knowledge Graph
| Target ID | CID | Compound Name | Gene ID | Gene Name | Species | Action | |
|---|---|---|---|---|---|---|---|
| dt1141 | 54675783 | Minocycline | 240 | ALOX5 | Homo sapiens (human) | Inhibitor | Details |
| dt1286 | 135413496 | Balsalazide Disodium | 240 | ALOX5 | Homo sapiens (human) | Arachidonate 5-lipoxygenase inhibitor | Details |
| dt1326 | 5339 | Sulfasalazine | 240 | ALOX5 | Homo sapiens (human) | Arachidonate 5-lipoxygenase inhibitor | Details |
| dt1333 | 5339 | Sulfasalazine | 240 | ALOX5 | Homo sapiens (human) | Inhibitor | Details |
| dt243 | 4075 | Mesalamine | 240 | ALOX5 | Homo sapiens (human) | Inhibitor | Details |
| dt467 | 14985 | Alpha-Tocopherol | 240 | ALOX5 | Homo sapiens (human) | -- | Details |
| dt524 | 54585 | Balsalazide | 240 | ALOX5 | Homo sapiens (human) | Inhibitor | Details |
| dt528 | 54585 | Balsalazide | 240 | ALOX5 | Homo sapiens (human) | -- | Details |
| dt731 | 5280492 | Leukotriene B4 | 240 | ALOX5 | Homo sapiens (human) | Quercetin 3-O-glucuronide inhibits the reaction [ALOX5 protein results in increased chemical synthesis of leukotriene b4]|quercetin 3'-sulfate inhibits the reaction [ALOX5 protein results in increased chemical synthesis of leukotriene b4]|luteolin inhibit | Details |
| dt732 | 5280492 | Leukotriene B4 | 240 | ALOX5 | Homo sapiens (human) | ALOX5 protein results in increased secretion of leukotriene B4 | Details |
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| Drug87 | LTB4 | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| Compound ID | Source ID | Source Type | Compound Name | Molecular Weight | Molecular Formula | Molecular Species | |
|---|---|---|---|---|---|---|---|
| No data available | |||||||
| Disease ID | Disease Name | Definition | Mechanism | |
|---|---|---|---|---|
| No data available | ||||
| Strategy ID | Therapy Strategy | Synonyms | Related Drugs | Mechanism | |
|---|---|---|---|---|---|
| No data available | |||||