IBD Research Resource Center

Target ID:	dt734
CID:	5280492
Compound Name:	Leukotriene B4
Gene ID:	240
Gene Name:	ALOX5
Species:	Homo sapiens (human)
PubMed IDs:	2849922
Action:	[tenidap results in decreased activity of ALOX5 protein] which results in decreased chemical synthesis of leukotriene b4\|[masoprocol results in decreased activity of ALOX5 protein] which results in decreased chemical synthesis of leukotriene B4\|[RS 43179

Knowledge Graph

Target ID	CID	Compound Name	Gene ID	Gene Name	Species	Action
dt1141	54675783	Minocycline	240	ALOX5	Homo sapiens (human)	Inhibitor	Details
dt1286	135413496	Balsalazide Disodium	240	ALOX5	Homo sapiens (human)	Arachidonate 5-lipoxygenase inhibitor	Details
dt1326	5339	Sulfasalazine	240	ALOX5	Homo sapiens (human)	Arachidonate 5-lipoxygenase inhibitor	Details
dt1333	5339	Sulfasalazine	240	ALOX5	Homo sapiens (human)	Inhibitor	Details
dt243	4075	Mesalamine	240	ALOX5	Homo sapiens (human)	Inhibitor	Details
dt467	14985	Alpha-Tocopherol	240	ALOX5	Homo sapiens (human)	--	Details
dt524	54585	Balsalazide	240	ALOX5	Homo sapiens (human)	Inhibitor	Details
dt528	54585	Balsalazide	240	ALOX5	Homo sapiens (human)	--	Details
dt730	5280492	Leukotriene B4	240	ALOX5	Homo sapiens (human)	ALOX5 protein promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased abundance of leukotriene b4]\|zileuton inhibits the reaction [ALOX5 protein promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased abundanc	Details
dt731	5280492	Leukotriene B4	240	ALOX5	Homo sapiens (human)	Quercetin 3-O-glucuronide inhibits the reaction [ALOX5 protein results in increased chemical synthesis of leukotriene b4]\|quercetin 3'-sulfate inhibits the reaction [ALOX5 protein results in increased chemical synthesis of leukotriene b4]\|luteolin inhibit	Details

Drug ID	Drug Name	Type	DrugBank ID	Targets	Category	Latest Progress
Drug87	LTB4	Chemical drug	--	--	--	Under clinical trials	Details

Compound ID	Source ID	Source Type	Compound Name	Molecular Weight	Molecular Formula	Molecular Species
No data available

Disease ID	Disease Name	Definition	Mechanism
No data available

Strategy ID	Therapy Strategy	Synonyms	Related Drugs	Mechanism
No data available