Experimental Models List
Source Distribution
Model Class Distribution
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Experimental Models List
| Model ID | Category | Classification | Type | Model | Description | Source | References | Details |
|---|---|---|---|---|---|---|---|---|
| M012 | Ex vivo | Tissue culture system | Gut-Ex-Vivo System (GEVS) | Gut-Ex-Vivo System (GEVS) | Silicone-based microfluidic device with 6 parallel isolated chambers, cultivates mouse colon tissue… | Mouse | 8301106 | Details |
| M001 | In vitro | Cell line | Tumor-derived cell line | Caco-2 | Immortalized human colorectal adenocarcinoma cells, differentiate into intestinal epithelial cells … | Human | 37519330 | Details |
| M010 | Ex vivo | Tissue culture system | Everted gut sac | Everted gut sac | Everted intestinal segments (duodenum, jejunum, ileum, colon) filled with Kreb’s solution, used for… | Rat | 37519330 | Details |
| M009 | Ex vivo | Tissue culture system | Ussing chamber | Ussing chamber | Two-compartment system with electrodes, measures ion transport, intestinal permeability, host-micro… | Human, Animal | 37519330 | Details |
| M008 | In vitro | Immunological co-culture | RAW 246.7 co-culture | RAW 246.7 | Mouse tumor-derived cell line (Abelson leukemia virus), mimics murine bone marrow-derived macrophag… | Mouse | 37519330 | Details |
| M007 | In vitro | Immunological co-culture | THP-1 co-culture | THP-1 | Human leukemia cell line derived from acute monocytic leukemia patient, similar to primary monocyte… | Human | 37519330 | Details |
| M006 | In vitro | Immunological co-culture | PBMC co-culture | PBMC | Isolated from peripheral blood or buffy coats of healthy donors, composed of dendritic cells, lymph… | Human | 37519330 | Details |
| M005 | In vitro | Cell line | Tumor-derived cell line | T84 | Human colon cancer-derived cell line, has microvilli, can develop into crypt-like cells when stimul… | Human | 37519330 | Details |
| M004 | In vitro | Co-culture cell model | Caco-2/HT29-MTX co-culture | Caco-2/HT29-MTX | Co-culture of Caco-2 (absorptive cells) and HT29-MTX (mucus-secreting goblet cells), ratios 90:10 o… | Human | 37519330 | Details |
| M003 | In vitro | Organoid | Intestinal organoid | Organoids | 3D structures derived from pluripotent or adult tissue stem cells (e.g., Lgr5+ ASCs), can different… | Human, Rodent | 37519330 | Details |