Experimental Models List

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Experimental Models List

Model ID Category Classification Type Model Description Source References Details
M001 In vitro Cell line Tumor-derived cell line Caco-2 Immortalized human colorectal adenocarcinoma cells, differentiate into intestinal epithelial cells … Human 37519330 Details
M002 In vitro Cell line Tumor-derived cell line HT29 Human colon cancer-derived cell line, can differentiate into enterocytes or mucus-generating cells,… Human 37519330 Details
M003 In vitro Organoid Intestinal organoid Organoids 3D structures derived from pluripotent or adult tissue stem cells (e.g., Lgr5+ ASCs), can different… Human, Rodent 37519330 Details
M004 In vitro Co-culture cell model Caco-2/HT29-MTX co-culture Caco-2/HT29-MTX Co-culture of Caco-2 (absorptive cells) and HT29-MTX (mucus-secreting goblet cells), ratios 90:10 o… Human 37519330 Details
M005 In vitro Cell line Tumor-derived cell line T84 Human colon cancer-derived cell line, has microvilli, can develop into crypt-like cells when stimul… Human 37519330 Details
M006 In vitro Immunological co-culture PBMC co-culture PBMC Isolated from peripheral blood or buffy coats of healthy donors, composed of dendritic cells, lymph… Human 37519330 Details
M007 In vitro Immunological co-culture THP-1 co-culture THP-1 Human leukemia cell line derived from acute monocytic leukemia patient, similar to primary monocyte… Human 37519330 Details
M008 In vitro Immunological co-culture RAW 246.7 co-culture RAW 246.7 Mouse tumor-derived cell line (Abelson leukemia virus), mimics murine bone marrow-derived macrophag… Mouse 37519330 Details
M009 Ex vivo Tissue culture system Ussing chamber Ussing chamber Two-compartment system with electrodes, measures ion transport, intestinal permeability, host-micro… Human, Animal 37519330 Details
M010 Ex vivo Tissue culture system Everted gut sac Everted gut sac Everted intestinal segments (duodenum, jejunum, ileum, colon) filled with Kreb’s solution, used for… Rat 37519330 Details