Model Information
| Model ID: | M020 |
|---|---|
| Category: | In vivo |
| Classification: | Chemically induced model |
| Type: | TNBS-induced colitis model |
| Source: | Rodents |
|---|---|
| References: | 24906689 |
Model Name
TNBS-induced colitis
Description
Hapten administered intrarectally (0.5–4.0 mg in 45–50% ethanol), induces delayed-type hypersensitivity reaction, resembles CD, clinical features include weight loss, bloody diarrhea, rectal prolapse, histological changes involve transmural inflammation,