Model Information
| Model ID: | M023 |
|---|---|
| Category: | In vivo |
| Classification: | Chemically induced model |
| Type: | Acetic acid-induced colitis model |
| Source: | Rodents |
|---|---|
| References: | 24906689 |
Model Name
Acetic acid-induced colitis
Description
Dilute acetic acid (4–50%) instilled rectally, induces acute UC-like colitis, dose-dependent ulceration, clinical features include weight loss, decreased mucous production, bowel wall thickening, histological changes involve epithelial necrosis, ulceratio