Model Information
| Model ID: | M025 |
|---|---|
| Category: | In vivo |
| Classification: | Chemically induced model |
| Type: | Indomethacin-induced enterocolitis model |
| Source: | Rodents |
|---|---|
| References: | 24906689 |
Model Name
Indomethacin-induced enterocolitis
Description
Indomethacin (7.5 mg/kg) administered subcutaneously, induces small intestinal and colonic ulceration resembling CD, clinical features include bowel wall thickening, mesenteric hemorrhage, mucosal ulcers, histological changes involve lymphoid hyperplasia,