Model Information
| Model ID: | M032 |
|---|---|
| Category: | In vivo |
| Classification: | Genetically engineered model (conventional knock-out) |
| Type: | IL-10-/- mice model |
| Source: | Mice |
|---|---|
| References: | 24906689 |
Model Name
IL-10-/- mice colitis
Description
IL-10 gene knock-out, spontaneous transmural pancolitis and cecal inflammation by 2–4 months of age, resembles CD, clinical features include intestinal inflammation, histological changes involve immune cell infiltration, ulceration