Model Information

Model ID: M034
Category: In vivo
Classification: Genetically engineered model (conventional knock-out)
Type: IL-2-/- mice model
Source: Mice
References: 24906689
Model Name

IL-2-/- mice colitis

Description

IL-2 gene knock-out, chronic colonic mucosa/submucosa inflammation by 8–9 weeks of age, resembles UC, clinical features include colonic ulcers, wall thickening, histological changes involve inflammatory cell infiltration