Model Information
| Model ID: | M035 |
|---|---|
| Category: | In vivo |
| Classification: | Genetically engineered model (conventional knock-out) |
| Type: | NOD2-/- mice model |
| Source: | Mice |
|---|---|
| References: | 24906689 |
Model Name
NOD2-/- mice colitis
Description
NOD2 gene knock-out, exhibits CD-like features, clinical features include intestinal inflammation, histological changes involve altered NF-κB activation, immune dysregulation