Model Information
| Model ID: | M036 |
|---|---|
| Category: | In vivo |
| Classification: | Genetically engineered model (conventional knock-out) |
| Type: | A20-/- mice model |
| Source: | Mice |
|---|---|
| References: | 24906689 |
Model Name
A20-/- mice colitis
Description
A20 gene knock-out, spontaneous colitis, cachexia, premature death, clinical features include intestinal inflammation, histological changes involve failure to terminate TNF-induced NF-κB responses