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Dysfunctional intestinal microvascular endothelial cells: Insights and therapeutic implications in gastrointestinal inflammation
Publication Year: 2024 Source: Immunometabolism (Cobham) PMID: 38818514
No Abstract
Insurer-Mandated Medication Utilization Barriers are Associated With Decreased Insurance Satisfaction and Adverse Clinical Outcomes: An Inflammatory Bowel Disease Partners Survey
Publication Year: 2024 Source: Am J Gastroenterol PMID: 38819004 DOI: 10.14309/ajg.0000000000002851
INTRODUCTION: Insurer-mandated barriers to timely initiation of advanced therapies used to treat inflammatory bowel disease (IBD) have been shown to worsen clinical outcomes and increase healthcare utilization, yet rarely alter the medication ultimately prescribed. METHODS: We conducted a survey within the IBD Partners longitudinal cohort to evaluate the frequency and …
Inflammatory biomarkers and psychological variables to assess quality of life in patients with inflammatory bowel disease: a cross-sectional study
Publication Year: 2024 Source: Ann Med PMID: 38819080 DOI: 10.1080/07853890.2024.2357738
BACKGROUND: Inflammatory bowel disease (IBD) is a chronic gastrointestinal condition. While inflammatory biomarkers are valuable for diagnosing and monitoring the disease, their correlation with patients' quality of life (QoL) is not well-established. PURPOSE: This study aims to investigate the correlations between inflammatory biomarkers and the quality of life (QoL) variables …
HIF-1α Pathway Orchestration by LCN2: A Key Player in Hypoxia-Mediated Colitis Exacerbation
Publication Year: 2024 Source: Inflammation PMID: 38819583 DOI: 10.1007/s10753-024-01990-y
In this study, we investigated the role of hypoxia in the development of chronic inflammatory bowel disease (IBD), focusing on its impact on the HIF-1alpha signaling pathway through the upregulation of lipocalin 2 (LCN2). Using a murine model of colitis induced by sodium dextran sulfate (DSS) under hypoxic conditions, transcriptome …
Long-term risk of cardiovascular disease associated with MASLD and different cardiometabolic risk factors in IBD patients: A prospective cohort study
Publication Year: 2024 Source: Liver Int PMID: 38819640 DOI: 10.1111/liv.15999
BACKGROUND: To examine the cardiovascular disease (CVD) risks associated with metabolic dysfunction-associated steatotic liver disease (MASLD) and different numbers of cardiometabolic risk factors (CMRFs) in patients with inflammatory bowel disease (IBD) based on a long-term prospective cohort. METHODS: Prevalent IBD patients at baseline who were free of CVD, cancer, alcoholic …
Patient interpretations of patient-reported outcome measures to assess bowel urgency: qualitative interviews in ulcerative colitis
Publication Year: 2024 Source: J Patient Rep Outcomes PMID: 38819757
No Abstract
Bacterial vampirism mediated through taxis to serum
Publication Year: 2024 Source: Elife PMID: 38820052
No Abstract
Micronutrient Deficiencies in Patients With Inflammatory Bowel Disease
Publication Year: 2024 Source: Cutis PMID: 38820096 DOI: 10.12788/cutis.0993
Inflammatory bowel disease (IBD) can cause micronutrient deficiencies that have cutaneous manifestations. Dermatologists may be the first to identify an undiagnosed micronutrient deficiency in the affected population. The approach to monitoring and repleting a micronutrient deficiency may be impacted by factors such as IBD activity and potential interactions between supplements …
An Oxidative Cleavage-Based Cruciform DNA Nanostructure for In Vivo Hypochlorous Acid Visualization to Monitor Intestinal Inflammation
Publication Year: 2024 Source: Anal Chem PMID: 38820543
No Abstract
DANCR maintained colon epithelial homeostasis by regulating the TNFα/NF-κB pathway
Publication Year: 2024 Source: Biochem Biophys Res Commun PMID: 38820627
No Abstract
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