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The potential of EGCG in modulating the oral-gut axis microbiota for treating inflammatory bowel disease

Publication Year: 2024 Source: Phytomedicine PMID: 38820660 DOI: 10.1016/j.phymed.2024.155643

Inflammatory bowel disease (IBD) is a recurrent chronic intestinal disorder that includes ulcerative colitis (UC) and Crohn's disease (CD). Its pathogenesis involves intricate interactions between pathogenic microorganisms, native intestinal microorganisms, and the intestinal immune system via the oral-gut axis. The strong correlation observed between oral diseases and IBD indicates the …

Oral administration of RDP58 ameliorated DSS-induced colitis in intestinal microbiota dependent manner

Publication Year: 2024 Source: Int Immunopharmacol PMID: 38820960 DOI: 10.1016/j.intimp.2024.112325

BACKGROUND: Although the pathogenesis of inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), has not been fully elucidated, accumulating researches suggest that intestinal microbiota imbalance contributes to the development of IBD in patients and animal models. RDP58, a peptide-based computer-assisted rational design, has been demonstrated to …

The evolutionarily ancient FOXA transcription factors shape the murine gut microbiome via control of epithelial glycosylation

Publication Year: 2024 Source: Dev Cell PMID: 38821056

No Abstract

Metabolic biomarkers in irritable bowel syndrome diagnosis

Publication Year: 2024 Source: Clin Chim Acta PMID: 38821336 DOI: 10.1016/j.cca.2024.119753

Irritable bowel syndrome (IBS) is a chronic gastrointestinal (GI) disorder characterized by altered bowel habits and abdominal discomfort during defecation. It significantly impacts life quality and work productivity for those affected. Global data suggests a slightly higher prevalence in females than in males. Today, unambiguous diagnosis of IBS remains challenging …

Healthcare resource utilization following ustekinumab initiation among bio-naïve Canadian patients with moderately-to-severely active Crohn's disease

Publication Year: 2024 Source: Dig Liver Dis PMID: 38821813 DOI: 10.1016/j.dld.2024.04.017

BACKGROUND/AIMS: Real-world healthcare resource utilization (HCRU) of bio-naive patients with Crohn's disease (CD) receiving ustekinumab was assessed. METHODS: A multicentre, retrospective chart review study of bio-naive Canadian adult patients with moderately-to-severely active CD treated with ustekinumab was conducted. CD-related HCRU (i.e., surgery, hospitalization, or emergency room [ER] visits) was evaluated …

Glowing insights: tracking vedolizumab in the mucosa of patients with IBD via molecular endoscopy

Publication Year: 2024 Source: Gut PMID: 38821860 DOI: 10.1136/gutjnl-2024-332503

No Abstract

Development and validation of a 13-item short version of the inflammatory bowel disease self-efficacy scale

Publication Year: 2024 Source: BMC Gastroenterol PMID: 38822266 DOI: 10.1186/s12876-024-03206-x

BACKGROUND: The inflammatory bowel disease self-efficacy scale (IBD-SES) is an instrument used across many countries to measure important health outcomes of patients with inflammatory bowel disease (IBD). We aimed to develop and validate a substantially shorter version of this scale to reduce patients' response burden. METHODS: A total of 919 …

Comparison of Fentanyl, Ketamine, and Lidocaine Combined with Propofol Anesthesia in Patients with Crohn Disease Undergoing Colonoscopy

Publication Year: 2024 Source: Med Sci Monit PMID: 38822518

No Abstract

An insight into the gut microbiota after Schistosoma japonicum eggs immunization in an experimental ulcerative colitis model

Publication Year: 2024 Source: FASEB J PMID: 38822662

No Abstract

Correction to: Implication of Inflammatory Bowel Disease Diagnosed Before the Age of 18 for Achieving an Upper Secondary Education: A Nationwide Population-Based Cohort Study

Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38822683

No Abstract

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