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From random to precise: updated colon cancer screening and surveillance for inflammatory bowel disease

Publication Year: 2024 Source: Transl Gastroenterol Hepatol PMID: 38716215 DOI: 10.21037/tgh-23-36

Patients with inflammatory bowel disease (IBD) are at increased risk of developing colorectal cancer (CRC). The pathogenesis of CRC in IBD differs from sporadic cancer, with the burden of inflammation being an important contributing factor. Other risk factors for developing CRC in patients with Crohn's disease (CD) or ulcerative colitis …

Crohn's disease treatment and memory T-cell subset changes: insights from a case series

Publication Year: 2024 Source: Transl Gastroenterol Hepatol PMID: 38716221

No Abstract

Predictive Factors of Non-Inflammatory Small Bowel Obstruction After Bowel Resection in Crohn's Patients

Publication Year: 2024 Source: Gastroenterology Res PMID: 38716284

No Abstract

Mucosa-Associated Lymphoid Tissue Surgeries as a Possible Risk for Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis

Publication Year: 2024 Source: Gastroenterology Res PMID: 38716286 DOI: 10.14740/gr1672

BACKGROUND: Inflammatory bowel disease (IBD) is a group of chronic inflammatory gastrointestinal disorders that are caused by genetic susceptibility and environmental factors and affects a significant portion of the global population. The gut-associated lymphoid tissue (GALT) is known to play a crucial role in immune modulation and maintaining gut microbiota …

Therapeutic sequencing in inflammatory bowel disease: Determining the optimal position of vedolizumab for long-term Crohn's disease control using real-world evidence

Publication Year: 2024 Source: United European Gastroenterol J PMID: 38717013 DOI: 10.1002/ueg2.12563

BACKGROUND: Several biologics are available for the treatment of moderate to severe Crohn's disease, but data to optimize their use are scarce. Vedolizumab (VDZ) is a gut-selective anti-lymphocyte trafficking monoclonal antibody that was approved in 2014 for the treatment of moderate to severe Crohn's disease. Based on real-world evidence, a …

Expanding ultrasound horizons in inflammatory bowel disease: Beyond the bowel

Publication Year: 2024 Source: United European Gastroenterol J PMID: 38717018

No Abstract

Utility of a Third Heplisav-B Dose in Patients With Inflammatory Bowel Disease Without Immunity After 2-Dose Heplisav-B Vaccination

Publication Year: 2024 Source: Am J Gastroenterol PMID: 38717045 DOI: 10.14309/ajg.0000000000002863

INTRODUCTION: Hepatitis B virus (HBV) vaccination is recommended in patients with inflammatory bowel disease (IBD). Although the 2-dose Heplisav-B vaccine has proven effective, more than 20% of patients with IBD do not seroconvert. We prospectively evaluated the effectiveness of a third Heplisav-B dose in patients with IBD lacking HBV immunity …

Fecal microbiota transplantation: current challenges and future landscapes

Publication Year: 2024 Source: Clin Microbiol Rev PMID: 38717124 DOI: 10.1128/cmr.00060-22

SUMMARYGiven the importance of gut microbial homeostasis in maintaining health, there has been considerable interest in developing innovative therapeutic strategies for restoring gut microbiota. One such approach, fecal microbiota transplantation (FMT), is the main "whole gut microbiome replacement" strategy and has been integrated into clinical practice guidelines for treating recurrent …

Multifaceted role of TRIM21 in inflammation

Publication Year: 2024 Source: Biol Futur PMID: 38717710

No Abstract

Ulcerative colitis and nephrotic syndrome: a two-sample Mendelian randomization study

Publication Year: 2024 Source: Intern Emerg Med PMID: 38717727

No Abstract

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