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Alterations in Gut Microbiota as Early Biomarkers for Predicting Inflammatory Bowel Disease Onset and Progression: A Systematic Review
Publication Year: 2024 Source: Cureus PMID: 38741828 DOI: 10.7759/cureus.58080
Inflammatory bowel disease (IBD) is a chronic ailment impacting the digestive system, triggered by an unusual reaction of the immune system. It includes two types of diseases: ulcerative colitis and Crohn's disease. Nonetheless, the diagnosis and evaluation of disease progression in IBD are difficult due to the absence of distinct …
Enteral nutrition compared with corticosteroids in children with Crohn's disease: A long-term nationwide study from the epi-IIRN
Publication Year: 2024 Source: Aliment Pharmacol Ther PMID: 38742605
No Abstract
Multiple Mucosal Ulcers Induced by Ixekizumab: A Case Report
Publication Year: 2024 Source: Ann Otol Rhinol Laryngol PMID: 38742650 DOI: 10.1177/00034894241254431
OBJECTIVES: Ixekizumab, an interleukin (IL)-17A inhibitor, exerts its therapeutic effects in psoriasis by inhibiting the interleukin (IL)-17 signaling pathway. Common adverse reactions to ixekizumab include injection site reactions and upper respiratory tract infections (URIs), while occurrences of inflammatory bowel disease (IBD) and multiple mucosal ulcers are infrequent. We present a …
Real-World Comparison of the Effectiveness between Ustekinumab and Vedolizumab in Patients with Ulcerative Colitis Exposed to at least One Anti-TNF Agent
Publication Year: 2024 Source: J Crohns Colitis PMID: 38742654
No Abstract
Bone marrow mesenchymal stromal cells support regeneration of intestinal damage in a colitis mouse model, independent of their CXCR4 expression
Publication Year: 2024 Source: Clin Transl Sci PMID: 38742709 DOI: 10.1111/cts.13821
Inflammatory bowel disease (IBD) is characterized by a chronically dysregulated immune response in the gastrointestinal tract. Bone marrow multipotent mesenchymal stromal cells have an important immunomodulatory function and support regeneration of inflamed tissue by secretion of soluble factors as well as through direct local differentiation. CXCR4 is the receptor for …
Unlocking the genetic tapestry of autoimmune diseases: Unveiling common genes across multiple conditions
Publication Year: 2024 Source: Int J Rheum Dis PMID: 38742742 DOI: 10.1111/1756-185X.15185
OBJECTIVES: This study aimed to unravel the complexities of autoimmune diseases by conducting a comprehensive analysis of gene expression data across 10 conditions, including systemic lupus erythematosus (SLE), psoriasis, Sjogren's syndrome, sclerosis, immune-associated diseases, osteoarthritis, cystic fibrosis, inflammatory bowel disease (IBD), type 1 diabetes, and Guillain-Barre syndrome. METHODS: Gene expression …
Authors' Response to Letter to Editor: "Evaluating Serum Free Thiols in Inflammatory Bowel Disease: Contribution of Albumin to Extracellular Free Thiol Status"
Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38742816
No Abstract
Berberine: Potential preventive and therapeutic strategies for human colorectal cancer
Publication Year: 2024 Source: Cell Biochem Funct PMID: 38742849
No Abstract
Identifying a therapeutic window of opportunity for people living with primary sclerosing cholangitis: Embryology and the overlap of inflammatory bowel disease with immune-mediated liver injury
Publication Year: 2024 Source: Hepatology PMID: 38743006 DOI: 10.1097/HEP.0000000000000926
Primary sclerosing cholangitis (PSC) is a variably progressive, fibrosis-causing autoimmune disorder of the intrahepatic and extrahepatic bile ducts of unclear etiology. PSC is commonly (in 60%-90% of cases) associated with an inflammatory bowel disease (IBD) like PSC-IBD and less commonly with an autoimmune hepatitis (AIH) like PSC-AIH or AIH-overlap disorder. …
The failure of biological treatment in axial spondyloarthritis is linked to the factors related to increased intestinal permeability and dysbiosis: prospective observational cohort study
Publication Year: 2024 Source: Rheumatol Int PMID: 38743252 DOI: 10.1007/s00296-024-05614-4
BACKGROUND: A significant number of patients with axial spondyloarthritis (axSpA) do not respond to biological therapy. Therefore, we decided to investigate the specificity of this group of patients and, in particular, whether haptoglobin (Hp), its polymorphism and zonulin, in addition to other clinical features, are predictors of poor response to …
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