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An immunohistochemical atlas of necroptotic pathway expression
Publication Year: 2024 Source: EMBO Mol Med PMID: 38750308 DOI: 10.1038/s44321-024-00074-6
Necroptosis is a lytic form of regulated cell death reported to contribute to inflammatory diseases of the gut, skin and lung, as well as ischemic-reperfusion injuries of the kidney, heart and brain. However, precise identification of the cells and tissues that undergo necroptotic cell death in vivo has proven challenging …
Artificial intelligence generated clinical score sheets: looking at the two faces of Janus
Publication Year: 2024 Source: Lab Anim Res PMID: 38750604
No Abstract
Efficacy and Safety of Ustekinumab for Chronic Pouchitis: A Prospective Open-label Multicenter Study
Publication Year: 2024 Source: Clin Gastroenterol Hepatol PMID: 38750870
No Abstract
Surgery for Crohn's Disease Is Associated With a Dysbiotic Microbiome and Metabolome: Results From Two Prospective Cohorts
Publication Year: 2024 Source: Cell Mol Gastroenterol Hepatol PMID: 38750900
No Abstract
Forecasted infliximab concentrations during induction predict time to remission and sustained disease control of inflammatory bowel disease
Publication Year: 2024 Source: Clin Res Hepatol Gastroenterol PMID: 38750934 DOI: 10.1016/j.clinre.2024.102374
BACKGROUND: Infliximab (IFX) exposure is established as a predictive factor of pharmacokinetic (PK) origin in inflammatory bowel disease (IBD), and expert consensus is to achieve adequate exposure during induction to achieve and sustain remission. METHODS: We retrospectively evaluated the performance of a Bayesian PK tool in IBD patients starting IFX. …
Ileal mucus viscoelastic properties differ in Crohn's disease
Publication Year: 2024 Source: Mucosal Immunol PMID: 38750968
No Abstract
Adequacy of sigmoidoscopy as compared to colonoscopy for assessment of disease activity in patients of ulcerative colitis: a prospective study
Publication Year: 2024 Source: Intest Res PMID: 38751349
No Abstract
Mangiferin, A Naturally Occurring Glucosylxanthone, Induces Apoptosis in Caco-2 Cells In Vitro and Exerts Protective Effects on Acetic Acid-Induced Ulcerative Colitis in Mice through the Regulation of NLRP3
Publication Year: 2024 Source: ACS Pharmacol Transl Sci PMID: 38751614 DOI: 10.1021/acsptsci.3c00323
Inflammatory bowel diseases (IBD), an inflammatory disease, include Crohn's disease and ulcerative colitis. Dysregulated autoimmune response to gut dysbiosis is mainly involved in the pathogenesis of IBD and is triggered by various inciting environmental factors. With its rising prevalence in every continent, IBD has evolved into a global disease, which …
AGA Clinical Practice Update on Management of Inflammatory Bowel Disease in Patients With Malignancy: Commentary
Publication Year: 2024 Source: Clin Gastroenterol Hepatol PMID: 38752967 DOI: 10.1016/j.cgh.2024.03.032
DESCRIPTION: The purpose of this American Gastroenterological Association (AGA) Institute Clinical Practice Update (CPU) Commentary is to discuss the risks of various malignancies in patients with inflammatory bowel diseases (IBD) and the impact of the available medical therapies on these risks. The CPU will also guide the approach to the …
Wogonin preconditioning of MSCs improved their therapeutic efficiency for colitis through promoting glycolysis
Publication Year: 2024 Source: Inflammopharmacology PMID: 38753221
No Abstract
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