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Causal relationship between primary biliary cholangitis and inflammatory bowel disease: a Mendelian randomization study

Publication Year: 2024 Source: Gastroenterol Rep (Oxf) PMID: 38766495 DOI: 10.1093/gastro/goae049

BACKGROUND: Several studies indicated that inflammatory bowel disease (IBD) may contribute to increased susceptibility to primary biliary cholangitis (PBC). However, the causal relationship between IBD and PBC remains unclear. METHODS: The genetic variant data of patients with IBD and PBC were obtained from published genome-wide association studies (GWASs). The IBD …

Case report: Inflammatory bowel disease triggered by secukinumab in a female case of axial spondyloarthritis accompanied with symptomatic epilepsy

Publication Year: 2024 Source: Int J Rheum Dis PMID: 38766681

No Abstract

Current Developments in the Prevention and Improvement of Intestinal Disorders: A Mini-Review

Publication Year: 2024 Source: Endocr Metab Immune Disord Drug Targets PMID: 38766826 DOI: 10.2174/0118715303285268240415040311

BACKGROUND: Recently, the number of patients who manifest intestinal disorders has increased. Particularly, Irritable Bowel Syndrome (IBS) patients and Inflammatory Bowel Disease (IBD) patients, which include Ulcerative Colitis (UC) and Crohn's Disease (CD), are on the rise, especially in the young generation. Behcet's disease (an autoimmune disease) and bowel obstruction …

Effectiveness and safety of a GLP-1 agonist in obese patients with inflammatory bowel disease

Publication Year: 2024 Source: Rev Esp Enferm Dig PMID: 38767015 DOI: 10.17235/reed.2024.10305/2024

BACKGROUND: obesity affects many patients with inflammatory bowel disease (IBD). Glucagon-like peptide (GLP)-1 agonists are a promising therapy for obese patients. However, there is a lack of evidence of the use of these drugs in IBD patients. This study investigated the effectiveness and safety of GLP-1 agonists in a cohort …

Magnetic Resonance Imaging Features Indicative of Permanent Colon Damage in Ulcerative Colitis: An Exploratory Study

Publication Year: 2024 Source: J Crohns Colitis PMID: 38767057 DOI: 10.1093/ecco-jcc/jjae075

BACKGROUND AND AIMS: It is uncertain whether ulcerative colitis leads to accumulated bowel damage on cross-sectional image. We aimed to characterise bowel damage in patients with ulcerative colitis using magnetic resonance imaging [MRI], and to determine its relation with duration of disease and the impact on patients' quality of life. …

Investigation of the active ingredients and mechanism of Shuangling extract in dextran sulfate sodium salt induced ulcerative colitis mice based on network pharmacology and experimental verification

Publication Year: 2024 Source: J Tradit Chin Med PMID: 38767631

No Abstract

4-Octyl itaconate alleviates dextran sulfate sodium-induced ulcerative colitis in mice via activating the KEAP1-NRF2 pathway

Publication Year: 2024 Source: Inflammopharmacology PMID: 38767761

No Abstract

Aegeline attenuates TNBS-induced colitis by suppressing the NFƙB-mediated NLRP3 inflammasome pathway in mice

Publication Year: 2024 Source: Inflammopharmacology PMID: 38767762

No Abstract

Legalization of Cannabis Does Not Reduce Opioid Prescribing in Patients With Inflammatory Bowel Disease: A Difference-in-Difference Analysis

Publication Year: 2024 Source: Am J Gastroenterol PMID: 38767951 DOI: 10.14309/ajg.0000000000002834

INTRODUCTION: Cannabis may provide inflammatory bowel disease (IBD) patients with an alternative to opioids for pain. METHODS: We conducted a difference-in-difference analysis using MarketScan. Changes over time in rates of opioid prescribing were compared in states with legalized cannabis to those without. RESULTS: We identified 6,240 patients with IBD in …

Short-Term Use of Upadacitinib in Combination With Biologic Therapy for Inducing Clinical Remission in Patients With Active Inflammatory Bowel Disease

Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38767984

No Abstract

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