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The role of neutral and adaptive evolutionary processes on patterns of genetic diversity across small cave-dwelling populations of Icelandic Arctic charr (Salvelinus alpinus)
Publication Year: 2024 Source: Ecol Evol PMID: 38770124 DOI: 10.1002/ece3.11363
Understanding the adaptability of small populations in the face of environmental change is a central problem in evolutionary biology. Solving this problem is challenging because neutral evolutionary processes that operate on historical and contemporary timescales can override the effects of selection in small populations. We assessed the effects of isolation …
[Analysis of predictive factors for non-adherence to organized screening for colorectal and breast cancers in the pre-pandemic period (2018-2019) in Lombardy Region (Northern Italy)]
Publication Year: 2024 Source: Epidemiol Prev PMID: 38770729 DOI: 10.19191/EP24.2.A720.039
BACKGROUND: according to the International Agency for Cancer Research on Cancer, in 2022, breast cancer is the most common cancer in the Italian population, followed by colorectal cancer. Oncological screenings represent an effective secondary prevention strategy to counteract colorectal and breast cancers, significantly reducing mortality. In Lombardy Region (Northern Italy), …
IL-22 regulates MASTL expression in intestinal epithelial cells
Publication Year: 2024 Source: Am J Physiol Gastrointest Liver Physiol PMID: 38771154 DOI: 10.1152/ajpgi.00260.2023
Microtubule-associated serine-threonine kinase-like (MASTL) has recently been identified as an oncogenic kinase given its overexpression in numerous cancers. Our group has shown that MASTL expression is upregulated in mouse models of sporadic colorectal cancer and colitis-associated cancer (CAC). CAC is one of the most severe complications of chronic inflammatory bowel …
Revisiting traditional practices in the management of acute uncomplicated diverticulitis: a call for change
Publication Year: 2024 Source: Int J Colorectal Dis PMID: 38771354
No Abstract
Transcultural adaptation and validation of IMPACT-III and IMPACT-III-P in Spanish families: a multicenter study from SEGHNP
Publication Year: 2024 Source: Eur J Pediatr PMID: 38771373 DOI: 10.1007/s00431-024-05575-7
IMPACT-III and IMPACT-III-P are health-related quality of life (HRQoL) questionnaires for patients with pediatric inflammatory bowel disease (p-IBD) and their parents/caregivers. We aimed to perform a transcultural adaptation and validation for the Spanish context. Translation, back-translation, and evaluation of the questionnaires were performed by an expert committee and 12 p-IBD …
Risk of heart failure in inflammatory bowel disease: a Swedish population-based study
Publication Year: 2024 Source: Eur Heart J PMID: 38771865 DOI: 10.1093/eurheartj/ehae338
BACKGROUND AND AIMS: Dysregulation of inflammatory and immune responses has been implicated in the pathogenesis of heart failure (HF). But even if inflammation is a prerequisite for inflammatory bowel disease (IBD), little is known about HF risk in IBD. METHODS: In this Swedish nationwide cohort, patients with biopsy-confirmed IBD were …
Factors Affecting Surgical Outcomes in Patients With IBD
Publication Year: 2024 Source: Dis Colon Rectum PMID: 38772019 DOI: 10.1097/DCR.0000000000003392
No Abstract
Alleviating depressive-like behavior in DSS-induced colitis mice: Exploring naringin and poncirin from Poncirus trifoliata extracts
Publication Year: 2024 Source: Biomed Pharmacother PMID: 38772154 DOI: 10.1016/j.biopha.2024.116770
Patients with inflammatory bowel diseases (IBDs), including ulcerative colitis (UC) and Crohn's disease (CD), often have concomitant mental disorders such as depression and anxiety. Therefore, a bidirectional approach involving the gut and brain axes is necessary for the prevention and treatment thereof. In this study, we explored the potential of …
Arbutin alleviates intestinal colitis by regulating neutrophil extracellular traps formation and microbiota composition
Publication Year: 2024 Source: Phytomedicine PMID: 38772182
No Abstract
Imatinib-induced ulcerative colitis
Publication Year: 2024 Source: J Oncol Pharm Pract PMID: 38772691
No Abstract
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