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The comparative anti-oxidant and anti-inflammatory efficacy of postbiotics and probiotics through Nrf-2 and NF-kB pathways in DSS-induced colitis model

Publication Year: 2024 Source: Sci Rep PMID: 38773299 DOI: 10.1038/s41598-024-62441-0

IBD is a disorder which could be caused by oxidative stress. This investigation aims to determine if probiotics and postbiotics can control oxidative stress and inflammation and compare the effectiveness of these two probiotic and postbiotic mixtures of substances. 88 strains of Lactobacillus and Bifidobacterium were tested for antioxidant activity. …

Dissecting causal relationships between primary biliary cholangitis and extrahepatic autoimmune diseases based on Mendelian randomization

Publication Year: 2024 Source: Sci Rep PMID: 38773317

No Abstract

Mogroside V reduced the excessive endoplasmic reticulum stress and mitigated the Ulcerative colitis induced by dextran sulfate sodium in mice

Publication Year: 2024 Source: J Transl Med PMID: 38773576

No Abstract

Experimental colitis in young Tg2576 mice accelerates the onset of an Alzheimer's-like clinical phenotype

Publication Year: 2024 Source: Alzheimers Res Ther PMID: 38773640

No Abstract

Inflammatory bowel disease and allergic diseases: A Mendelian randomization study

Publication Year: 2024 Source: Pediatr Allergy Immunol PMID: 38773751 DOI: 10.1111/pai.14147

BACKGROUND: Inflammatory bowel disease (IBD) and allergic diseases possess similar genetic backgrounds and pathogenesis. Observational studies have shown a correlation, but the exact direction of cause and effect remains unclear. The aim of this Mendelian randomization (MR) study is to assess bidirectional causality between inflammatory bowel disease and allergic diseases. …

Editorial: Infliximab induction therapy in pediatric Crohn's disease-A cost-effective strategy?

Publication Year: 2024 Source: Aliment Pharmacol Ther PMID: 38773786

No Abstract

Editorial: Infliximab induction therapy in paediatric Crohn's disease - A cost-effective strategy? Authors' reply

Publication Year: 2024 Source: Aliment Pharmacol Ther PMID: 38773791

No Abstract

Causal association of blood cell traits with inflammatory bowel diseases: a Mendelian randomization study

Publication Year: 2024 Source: Front Nutr PMID: 38774261

No Abstract

The shared circulating diagnostic biomarkers and molecular mechanisms of systemic lupus erythematosus and inflammatory bowel disease

Publication Year: 2024 Source: Front Immunol PMID: 38774864 DOI: 10.3389/fimmu.2024.1354348

BACKGROUND: Systemic lupus erythematosus (SLE) is a multi-organ chronic autoimmune disease. Inflammatory bowel disease (IBD) is a common chronic inflammatory disease of the gastrointestinal tract. Previous studies have shown that SLE and IBD share common pathogenic pathways and genetic susceptibility, but the specific pathogenic mechanisms remain unclear. METHODS: The datasets …

Investigation of the causal association between Parkinson's disease and autoimmune disorders: a bidirectional Mendelian randomization study

Publication Year: 2024 Source: Front Immunol PMID: 38774879

No Abstract

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