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Challenges in IBD Research 2024: Precision Medicine

Publication Year: 2024 Source: Inflamm Bowel Dis PMID: 38778628 DOI: 10.1093/ibd/izae084

Precision medicine is part of 5 focus areas of the Challenges in IBD Research 2024 research document, which also includes preclinical human IBD mechanisms, environmental triggers, novel technologies, and pragmatic clinical research. Building on Challenges in IBD Research 2019, the current Challenges aims to provide a comprehensive overview of current …

Research advancements and perspectives of inflammatory bowel disease: A comprehensive review

Publication Year: 2024 Source: Sci Prog PMID: 38778725 DOI: 10.1177/00368504241253709

Inflammatory bowel disease (IBD) is a chronic inflammatory disease with increasing incidence, such as Crohn's disease and ulcerative colitis. The accurate etiology and pathogenesis of IBD remain unclear, and it is generally believed that it is related to genetic susceptibility, gut microbiota, environmental factors, immunological abnormalities, and potentially other factors. …

Current Knowledge on the Preparation and Benefits of Cruciferous Vegetables as Relates to In Vitro, In Vivo, and Clinical Models of Inflammatory Bowel Disease

Publication Year: 2024 Source: Curr Dev Nutr PMID: 38779039

No Abstract

Effect of a gamified mobile-based self-management application on disease activity index, quality of life, and mental health in adults with inflammatory bowel disease: A protocol of a randomized controlled trial study

Publication Year: 2024 Source: Health Sci Rep PMID: 38779219 DOI: 10.1002/hsr2.2109

BACKGROUND AND AIMS: Inflammatory bowel disease (IBD) is a chronic inflammatory gastrointestinal tract disease subdivided into Crohn's disease (CD) and ulcerative colitis (UC). There is currently no cure for IBD, and individuals with IBD frequently experience a lower health-related quality of life (HRQOL) than the general population. Gamification has become …

Role of Healthy Lifestyle and Diet Quality in the Development of Colorectal Cancer in the Adult Population in the Kurdistan Region: A Case-Control Study

Publication Year: 2024 Source: Cureus PMID: 38779268 DOI: 10.7759/cureus.58764

Background The incidence of colorectal cancer (CRC) is increasing in developing countries. The factors contributing to the risk of CRC are not known in developing countries. Therefore, this study aimed to explore the role of a healthy lifestyle on CRC in the adult population in the Kurdistan Region of Iraq. …

An Unusual Cause of Intestinal Ulcers Masquerading as Inflammatory Bowel Disease: A Case Report of Allied Disorders of Hirschsprung's Disease

Publication Year: 2024 Source: J Inflamm Res PMID: 38779428

No Abstract

The Impact of Microbiome Interventions on the Progression and Severity of Inflammatory Bowel Disease: A Systematic Review

Publication Year: 2024 Source: Cureus PMID: 38779440 DOI: 10.7759/cureus.60786

Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), is characterized by chronic intestinal inflammation. The dysbiotic gut microbiome likely contributes to IBD pathogenesis. Microbiome-directed therapies such as fecal microbiota transplantation (FMT), probiotics, and synbiotics may help induce and maintain remission. This systematic review aimed to determine …

Amyloid, Crohn's disease, and Alzheimer's disease - are they linked?

Publication Year: 2024 Source: Front Cell Infect Microbiol PMID: 38779559

No Abstract

An integrative multi-omic analysis defines gut microbiota, mycobiota, and metabolic fingerprints in ulcerative colitis patients

Publication Year: 2024 Source: Front Cell Infect Microbiol PMID: 38779566 DOI: 10.3389/fcimb.2024.1366192

BACKGROUND: Ulcerative colitis (UC) is a multifactorial chronic inflammatory bowel disease (IBD) that affects the large intestine with superficial mucosal inflammation. A dysbiotic gut microbial profile has been associated with UC. Our study aimed to characterize the UC gut bacterial, fungal, and metabolic fingerprints by omic approaches. METHODS: The 16S …

Corrigendum: Identifying predictors of clinical outcomes using the projection-predictive feature selection-a proof of concept on the example of Crohn's disease

Publication Year: 2024 Source: Front Pediatr PMID: 38779577

No Abstract

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