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Simultaneous Treatment of 5-Aminosalicylic Acid and Treadmill Exercise More Effectively Improves Ulcerative Colitis in Mice
Publication Year: 2024 Source: Int J Mol Sci PMID: 38791116
No Abstract
Restoration of Lactobacillus johnsonii and Enterococcus faecalis Caused the Elimination of Tritrichomonas sp. in a Model of Antibiotic-Induced Dysbiosis
Publication Year: 2024 Source: Int J Mol Sci PMID: 38791132 DOI: 10.3390/ijms25105090
Inflammatory bowel disease (IBD) is a multifactorial disease involving the interaction of the gut microbiota, genes, host immunity, and environmental factors. Dysbiosis in IBD is associated with pathobiont proliferation, so targeted antibiotic therapy is a rational strategy. When restoring the microbiota with probiotics, it is necessary to take into account …
Multi-Omics Characterization of Colon Mucosa and Submucosa/Wall from Crohn's Disease Patients
Publication Year: 2024 Source: Int J Mol Sci PMID: 38791146 DOI: 10.3390/ijms25105108
Crohn's disease (CD) is a subtype of inflammatory bowel disease (IBD) characterized by transmural disease. The concept of transmural healing (TH) has been proposed as an indicator of deep clinical remission of CD and as a predictor of favorable treatment endpoints. Understanding the pathophysiology involved in transmural disease is critical …
The Role of Wheatgrass in Colorectal Cancer: A Review of the Current Evidence
Publication Year: 2024 Source: Int J Mol Sci PMID: 38791211
No Abstract
Modulation of Serotonin-Related Genes by Extracellular Vesicles of the Probiotic Escherichia coli Nissle 1917 in the Interleukin-1β-Induced Inflammation Model of Intestinal Epithelial Cells
Publication Year: 2024 Source: Int J Mol Sci PMID: 38791376 DOI: 10.3390/ijms25105338
Inflammatory bowel disease (IBD) is a chronic inflammatory condition involving dysregulated immune responses and imbalances in the gut microbiota in genetically susceptible individuals. Current therapies for IBD often have significant side-effects and limited success, prompting the search for novel therapeutic strategies. Microbiome-based approaches aim to restore the gut microbiota balance …
Gut Microbiota Profile Changes in Patients with Inflammatory Bowel Disease and Non-Alcoholic Fatty Liver Disease: A Metagenomic Study
Publication Year: 2024 Source: Int J Mol Sci PMID: 38791490 DOI: 10.3390/ijms25105453
Gut microbiota imbalances have a significant role in the pathogenesis of Inflammatory Bowel Disease (IBD) and Non-Alcoholic Fatty Liver Disease (NAFLD). Herein, we compared gut microbial composition in patients diagnosed with either IBD or NAFLD or a combination of both. Seventy-four participants were stratified into four groups: IBD-NAFLD, IBD-only, NAFLD-only …
Insights into Therapeutic Response Prediction for Ustekinumab in Ulcerative Colitis Using an Ensemble Bioinformatics Approach
Publication Year: 2024 Source: Int J Mol Sci PMID: 38791570
No Abstract
The Effect of Methyl-Derivatives of Flavanone on MCP-1, MIP-1β, RANTES, and Eotaxin Release by Activated RAW264.7 Macrophages
Publication Year: 2024 Source: Molecules PMID: 38792101 DOI: 10.3390/molecules29102239
Chemokines, also known as chemotactic cytokines, stimulate the migration of immune cells. These molecules play a key role in the pathogenesis of inflammation leading to atherosclerosis, neurodegenerative disorders, rheumatoid arthritis, insulin-resistant diabetes, and cancer. Moreover, they take part in inflammatory bowel disease (IBD). The main objective of our research was …
Inflammatory Bowel Diseases in the Elderly: A Focus on Disease Characteristics and Biological Therapy Patterns
Publication Year: 2024 Source: J Clin Med PMID: 38792308 DOI: 10.3390/jcm13102767
Background: The incidence of inflammatory bowel diseases (IBDs) in elderly patients is constantly increasing. It results from the combination of an aging population with compounding prevalence of IBD, as well as the growing burden of elderly-onset IBD. The clinical characteristics of elderly patients differ from young subjects with IBD due …
Are Internet Information Sources Helpful for Adult Crohn's Disease Patients Regarding Nutritional Advice?
Publication Year: 2024 Source: J Clin Med PMID: 38792376 DOI: 10.3390/jcm13102834
Background: Adult patients suffering from Crohn's disease (CD) are often dissatisfied with the information they receive from their physicians about nutrition and its impact on CD inflammation activity. Only a few publications are available about patients' internet research on nutrition in CD. The study aim is to elucidate the internet …
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