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Single-Cell Transcriptomic and Targeted Genomic Profiling Adjusted for Inflammation and Therapy Bias Reveal CRTAM and PLCB1 as Novel Hub Genes for Anti-Tumor Necrosis Factor Alpha Therapy Response in Crohn's Disease
Publication Year: 2024 Source: Pharmaceutics PMID: 38931955
No Abstract
Acute and Long COVID Intestinal Changes in an Experimental Model of Coronavirus in Mice
Publication Year: 2024 Source: Viruses PMID: 38932125 DOI: 10.3390/v16060832
The COVID-19 pandemic, which emerged in early 2020, has had a profound and lasting impact on global health, resulting in over 7.0 million deaths and persistent challenges. In addition to acute concerns, there is growing attention being given to the long COVID health consequences for survivors of COVID-19 with documented …
Resistant starch and tannic acid synergistically ameliorated dextran sulfate sodium-induced ulcerative colitis, particularly in the distal colon
Publication Year: 2024 Source: Food Funct PMID: 38932628
No Abstract
Life changes, self-prevention, knowledge and mental health among inflammatory bowel disease patients during COVID-19 pandemic: a cross-sectional study
Publication Year: 2024 Source: Front Public Health PMID: 38932786 DOI: 10.3389/fpubh.2024.1416880
BACKGROUND: With the COVID-19 pandemic going to be COVID-19 endemic, the negative impact of COVID-19 on the mental health of IBD patients cannot be ignored. This study aimed to investigate the occurrence of anxiety and depression in IBD patients during the COVID-19 pandemic and analyze the factors associated with mental …
Cellular succinate metabolism and signaling in inflammation: implications for therapeutic intervention
Publication Year: 2024 Source: Front Immunol PMID: 38933270
No Abstract
Fecal microbiota and concentrations of long-chain fatty acids, sterols, and unconjugated bile acids in cats with chronic enteropathy
Publication Year: 2024 Source: Front Vet Sci PMID: 38933703 DOI: 10.3389/fvets.2024.1401592
Feline chronic enteropathies (FCE) are common causes of chronic gastrointestinal signs in cats and include different diseases such as food-responsive enteropathy (FRE), inflammatory bowel diseases (IBD), and low-grade intestinal T-cell lymphoma (LGITL). Although changes in intestinal microbiota and fecal metabolites have been reported in dogs and humans with chronic enteropathy, …
Diagnosis and management of inflammatory bowel disease
Publication Year: 2024 Source: J Evid Based Med PMID: 38934234 DOI: 10.1111/jebm.12626
Inflammatory bowel disease (IBD) is a chronic and relapsing immune-mediated disease of the gastrointestinal tract with a gradually increasing global incidence and prevalence. A prolonged course of IBD leads to a decline in patient quality of life and the creation of a substantial economic burden on society. Owing to the …
The diverse roles of sphingolipids in inflammatory bowel disease
Publication Year: 2024 Source: FASEB J PMID: 38934445 DOI: 10.1096/fj.202400830R
The incidence of inflammatory bowel disease (IBD) has increased over the last 20 years. A variety of causes, both physiological and environmental, contribute to the initiation and progression of IBD, making disease management challenging. Current treatment options target various aspects of the immune response to dampen intestinal inflammation; however, their …
Decreased Serum Tryptophan and Severe Ulcerative Damage of Colon Mucosa Identify Inflammatory Bowel Disease Patients With High Risk of Cytomegalovirus Colitis
Publication Year: 2024 Source: Clin Transl Gastroenterol PMID: 38934504 DOI: 10.14309/ctg.0000000000000731
No Abstract
Insights into the Enhanced Bioavailability of Per- and Polyfluoroalkyl Substances in Food Caused by Chronic Inflammatory Bowel Disease
Publication Year: 2024 Source: Environ Sci Technol PMID: 38934536 DOI: 10.1021/acs.est.4c01511
Understanding the bioavailability of per- and polyfluoroalkyl substances (PFAS) in food is essential for accurate human health risk assessment. Given the rising incidence of inflammatory bowel disease (IBD), this study aimed to investigate the impacts of IBD on the bioavailability of PFAS in food using mice models. The relative bioavailability …
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