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Metabolic health and genetic predisposition in inflammatory bowel disease: Insights from a prospective cohort study
Publication Year: 2024 Source: Eur J Intern Med PMID: 38955589 DOI: 10.1016/j.ejim.2024.06.020
BACKGROUND: Metabolic disorders exhibit strong inflammatory underpinnings and vice versa. This study aimed to investigate the association between metabolic health status, genetic predisposition, and the risk of inflammatory bowel disease (IBD), and to explore the potential benefits of maintaining ideal metabolic status for individuals with a predetermined genetic risk of …
2023 Chinese national clinical practice guideline on diagnosis and management of Crohn's disease
Publication Year: 2024 Source: Chin Med J (Engl) PMID: 38955665
No Abstract
[Value of histological activity in predicting endoscopic relapse among patients of ulcerative colitis in endoscopic remission]
Publication Year: 2024 Source: Zhonghua Bing Li Xue Za Zhi PMID: 38955703
No Abstract
ETS2 regulates human inflammatory macrophages in IBD
Publication Year: 2024 Source: Nat Rev Gastroenterol Hepatol PMID: 38956300 DOI: 10.1038/s41575-024-00960-x
No Abstract
Life's essential 8, genetic susceptibility, and risk of inflammatory bowel diseases: a population-based cohort study
Publication Year: 2024 Source: Int J Behav Nutr Phys Act PMID: 38956566 DOI: 10.1186/s12966-024-01617-3
BACKGROUND: Evidence has shown that the individual metrics in Life's Essential 8 (LE8), an updated cardiovascular health (CVH) concept proposed by the American Heart Association, play a role in the development of inflammatory bowel disease (IBD). However, epidemiological evidence on the overall LE8 on IBD risk remains limited. We aimed …
Mesenteric lymph nodes: a critical site for the up-regulatory effect of hUC-MSCs on Treg cells by producing TGF-β1 in colitis treatment
Publication Year: 2024 Source: Stem Cell Res Ther PMID: 38956621 DOI: 10.1186/s13287-024-03809-x
BACKGROUND: Mesenchymal stem cells (MSCs) demonstrate a wide range of therapeutic capabilities in the treatment of inflammatory bowel disease (IBD). The intraperitoneal injection of MSCs has exhibited superior therapeutic efficacy on IBD than intravenous injection. Nevertheless, the precise in vivo distribution of MSCs and their biological consequences following intraperitoneal injection …
From diversity to disease: unravelling the role of enteric glial cells
Publication Year: 2024 Source: Front Immunol PMID: 38957473 DOI: 10.3389/fimmu.2024.1408744
Enteric glial cells (EGCs) are an essential component of the enteric nervous system (ENS) and play key roles in gastrointestinal development, homeostasis, and disease. Derived from neural crest cells, EGCs undergo complex differentiation processes regulated by various signalling pathways. Being among the most dynamic cells of the digestive system, EGCs …
Faecalibaterium prausnitzii strain EXL01 boosts efficacy of immune checkpoint inhibitors
Publication Year: 2024 Source: Oncoimmunology PMID: 38957477
No Abstract
Recent advances in measuring the effects of diet on gastrointestinal physiology: Probing the "leaky gut" and application of real-time ultrasound
Publication Year: 2024 Source: JGH Open PMID: 38957479
No Abstract
Revolution in diet therapy for inflammatory bowel disease
Publication Year: 2024 Source: JGH Open PMID: 38957480 DOI: 10.1002/jgh3.13097
Until recently, diet as a therapeutic tool to treat inflammatory bowel disease (IBD) has not been proven effective. Nearly a century in the making we are in the grips of a revolution in diet therapies for IBD, driven by emerging data revealing diet as a key environmental factor associated with …
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