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The protective role of PYY in intestinal mucosal defects induced by SATB2 deficiency in inflammatory bowel disease
Publication Year: 2025 Source: Cell Death Discov PMID: 40340969 DOI: 10.1038/s41420-025-02511-y
Impaired colonic mucosal repair is a critical issue in inflammatory bowel diseases (IBD). SATB2 is essential for maintaining colonic epithelial homeostasis, but its role in mucosal repair is unclear. In this study, flow cytometry was used to assess SATB2's role in colonic epithelial repair in a radiation injury model. SATB2 …
Sleep tracking and sleep hygiene counseling improve fatigue in pediatric patients with inflammatory bowel disease
Publication Year: 2025 Source: J Pediatr Gastroenterol Nutr PMID: 40341610 DOI: 10.1002/jpn3.70066
OBJECTIVES: While the presence of fatigue and inadequate sleep are well-described in children with inflammatory bowel disease (IBD), little data exist on potential sleep improvement interventions. We aimed to determine if sleep tracking and sleep hygiene counseling can result in sleep behavior change and reduced fatigue in children/adolescents with IBD. …
Letter: Are Antispasmodics Truly Ineffective in IBD? Considerations on Nuanced Interpretation and Stratified Analysis. Authors' Reply
Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 40341675 DOI: 10.1111/apt.70186
No Abstract
Effect of Qingchang Yuyang decoction on treatment efficacy and intestinal flora in patients with ulcerative colitis
Publication Year: 2025 Source: Allergol Immunopathol (Madr) PMID: 40342115
This study investigates the therapeutic effects of Qingchang Yuyang Decoction on ulcerative colitis (UC) and its impact on intestinal flora. Using existing case records, a retrospective analysis was conducted utilizing clinical data from 96 UC patients (damp-heat syndrome of the large intestine) treated at our hospital between June 2022 and …
Letter: Are Antispasmodics Truly Ineffective in IBD? Considerations on Nuanced Interpretation and Stratified Analysis
Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 40342134 DOI: 10.1111/apt.70168
No Abstract
Isobutyrate Confers Resistance to Inflammatory Bowel Disease through Host-Microbiota Interactions in Pigs
Publication Year: 2025 Source: Research (Wash D C) PMID: 40342298 DOI: 10.34133/research.0673
Supplementation with short-chain fatty acids (SCFAs) is a potential therapeutic approach for inflammatory bowel disease (IBD). However, the therapeutic effects and mechanisms of action of isobutyrate in IBD remain unclear. Clinical data indicate that the fecal levels of isobutyrate are markedly lower in patients with Crohn's disease than in healthy …
Importance of Enteral Feeding: Enhancing Patient Care through Interventional Radiology
Publication Year: 2025 Source: Semin Intervent Radiol PMID: 40342379
Enteral feeding plays a vital role for patients who are unable to meet their nutritional needs through oral intake, providing benefit to those with conditions such as inflammatory bowel disease, postsurgical recovery, chronic dysphagia, dysfunctional gastrointestinal tract, and critical illness. The role of interventional radiologists in enteral access is expanding, …
Circular RNAs in inflammatory bowel disease: a review of mechanisms, biomarkers and therapeutic potential
Publication Year: 2025 Source: Front Immunol PMID: 40342413 DOI: 10.3389/fimmu.2025.1540768
Inflammatory bowel disease (IBD) is an autoimmune disease of unknown etiology characterized by recurrent chronic inflammation of the gastrointestinal tract. The incidence of IBD is increasing and has become a focus of research on digestive diseases. Despite advances in understanding its multifactorial etiology, including genetic predisposition, microbiome dysbiosis, and immune …
Developing IBD counsellors in low- and middle-income countries: bridging gaps in patient care
Publication Year: 2025 Source: EClinicalMedicine PMID: 40342568 DOI: 10.1016/j.eclinm.2025.103218
The global burden of inflammatory bowel disease (IBD) is progressively increasing, with a particularly sharp rise in newly industrialized and resource-limited settings. These regions face unique and pressing challenges in IBD care, including a shortage of trained specialists, delayed or missed diagnoses, financial and geographic barriers to access, and the …
Thyroid dysfunction in MASLD: Results of a nationwide study
Publication Year: 2025 Source: JHEP Rep PMID: 40342634 DOI: 10.1016/j.jhepr.2025.101369
BACKGROUND & AIMS: Thyroid hormones are known to be potent modulators of hepatic metabolism and targeting the thyroid hormone receptor was recently approved as the first treatment for metabolic-associated steatotic liver disease (MASLD); however, the exact relationship between thyroid disorders and biopsy-confirmed MASLD remains unclear. METHODS: We conducted a nationwide …
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