Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
Anti-integrin αvβ6 IgG antibody as a diagnostic and prognostic marker in ulcerative colitis: A cross-sectional and longitudinal study defining a specific disease phenotype
Publication Year: 2025 Source: J Crohns Colitis PMID: 40251889 DOI: 10.1093/ecco-jcc/jjaf062
BACKGROUND AND AIMS: The diagnostic and prognostic properties of anti-integrin alphavbeta6 immunoglobulin G (IgG) autoantibodies in ulcerative colitis (UC) are poorly understood. We aimed to assess the diagnostic performance of anti-integrin alphavbeta6 autoantibodies and examine their association with disease outcomes. METHODS: Serum samples from a Swedish inception cohort of patients …
Hidradenitis suppurativa among patients with new-onset inflammatory bowel disease-results from the IBD Prognosis Study
Publication Year: 2025 Source: J Crohns Colitis PMID: 40251895 DOI: 10.1093/ecco-jcc/jjaf066
BACKGROUND AND AIMS: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease associated with inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC). This study aimed to assess the prevalence and clinical characteristics of HS in a population-based cohort of newly diagnosed IBD patients. METHODS: The Copenhagen …
Triple biologic therapy for refractory Crohn's disease
Publication Year: 2025 Source: J Crohns Colitis PMID: 40251965
BACKGROUND: Despite significant advances in the therapeutic management of Crohn's disease (CD), a subset of patients remains refractory to available treatments. Dual-targeted therapy (DTT), combining biologics or biologics with small molecules, has emerged as a promising approach. While evidence supporting DTT continues to grow, reports of patients treated with a …
Faecalibacterium Diversity in the Gut Microbiome of Crohn's Disease Patients
Publication Year: 2025 Source: United European Gastroenterol J PMID: 40252217 DOI: 10.1002/ueg2.70023
Faecalibacterium has recently garnered attention for its potential health implications. To better understand its role, we developed and assessed real-time PCR assays for detecting and quantifying various Faecalibacterium species in human stool samples from both healthy individuals and Crohn's disease patients, either in flare or remission. The assays targeted the …
Autoimmunity in inflammatory bowel disease: a holobiont perspective
Publication Year: 2025 Source: Curr Opin Immunol PMID: 40252635 DOI: 10.1016/j.coi.2025.102557
Adaptive immunity towards self-antigens (autoimmunity) and intestinal commensal microbiota is a key feature of inflammatory bowel disease (IBD). Considering mucosal adaptive immunity from a holobiont perspective, where the host and its microbiome form a single physiological unit, emphasises the challenge of avoiding damaging responses to self-antigen and symbiotic microbial communities …
1000-plex antibody array proteomic screen uncovers PGRPS, Haptoglobin, Serpin A4 and Fibrinogen as potential stool biomarkers of pediatric inflammatory bowel disease
Publication Year: 2025 Source: Clin Immunol PMID: 40252987 DOI: 10.1016/j.clim.2025.110495
Easy to obtain and in close proximity to the affected areas, fecal samples offer significant potential for the advancement of non-invasive diagnostic methods for inflammatory bowel disease (IBD). A cross-sectional antibody array-based proteomic screen of 1000 fecal protein biomarkers was conducted using stool from treatment naive control, Crohn's disease (CD), …
Dietary emulsifier Polysorbate 80-induced lipotoxicity promotes intestinal senescence
Publication Year: 2025 Source: Food Res Int PMID: 40253120
Intestinal senescence, often characterized by increased oxidative stress, is linked to gastrointestinal disorders such as inflammatory bowel disease and colorectal cancer. While previous studies have suggested that diets rich in food additives, such as the emulsifier Polysorbate 80 (P80), may influence gut health, the impact of P80 exposure on intestinal …
Long-term soy dietary fiber diet modifies the intestinal internal environment: Focus on chronic ulcerative colitis
Publication Year: 2025 Source: Food Res Int PMID: 40253171
Okara is a major by-product of soybean processing, which not only has negative impacts on the environment but also leads to resource waste. Soybean residue is rich in insoluble dietary fiber, which is known to have a positive effect on ulcerative colitis. This study aimed to investigate whether long-term consumption …
CiLi (Rosa roxburghii Tratt.) polyphenols improve colitis via gut microbiota-lipid mediator-immunity axis
Publication Year: 2025 Source: Food Res Int PMID: 40253185 DOI: 10.1016/j.foodres.2025.116257
Dysbiosis of gut microbiome is one of the most important factors leading to inflammatory bowel disease (IBD). Intake of phytochemicals from fruits and vegetables is an effective way to improve IBD, but how these bioactivators regulate gut microbiota to exert healthy effects remains unclear. Here, we found that pretreatment with …
Risk factors for residual tumors in histologically incompletely resected rectal neuroendocrine tumors
Publication Year: 2025 Source: Dig Liver Dis PMID: 40253226
BACKGROUND: Rectal neuroendocrine tumors (r-NETs) are often misidentified as polyps, leading to inappropriate endoscopic treatment and incomplete resection. AIMS: This study investigated the occurrence and risk factors of residual r-NETs following salvage local resection (SLR) after incomplete resection. METHODS: The medical records of 95 patients who underwent SLR for histologically …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide