Research Articles Library
Literature Analysis Tools
Advanced Search
Filter by PMID, year, source, DOI and other criteria
Literature Analysis
Analyze research trends and hotspots
Batch Export
Export search results to Excel/PDF
New challenges in the management of inflammatory bowel disease: a case study
Publication Year: 2025 Source: Prz Gastroenterol PMID: 40191511
No Abstract
Investigation of Some Long Noncoding RNAs (LncRNAs) in Pediatric Inflammatory Bowel Disease (IBD): An Iranian Study
Publication Year: 2025 Source: Biochem Res Int PMID: 40191802 DOI: 10.1155/bri/8879418
Introduction: According to the importance of long noncoding RNAs (LncRNA) in the pathogenesis of inflammatory bowel disease (IBD) and also the lack of study for pediatric IBD in this regard, we investigated the expression of a selected panel of LncRNAs in Iranian pediatric cases of IBD compared to adult cases …
Existential Reflections by Older Adults With Inflammatory Bowel Diseases on Medical and Surgical Treatments
Publication Year: 2025 Source: Am J Gastroenterol PMID: 40192128 DOI: 10.14309/ajg.0000000000003475
INTRODUCTION: Current treatment guidelines do not address the unique health risks or life priorities of the aging population with inflammatory bowel diseases (IBD). Patient priority-directed care approaches can facilitate better clinical management for this population. We aimed to explore the experiences of older adults with IBD in relation with medical …
Long-Term Sustained Improvement in Unplanned Healthcare Utilization in Patients With Inflammatory Bowel Disease
Publication Year: 2025 Source: Am J Gastroenterol PMID: 40192134 DOI: 10.14309/ajg.0000000000003454
INTRODUCTION: Inflammatory bowel diseases are associated with unpredictable disease exacerbation and need for urgent care. We aimed to assess long-term sustained improvement in emergency department utilization after completion of a multicenter quality improvement (QI) initiative. METHODS: After the QI initiative, we developed an "urgent care toolkit" for sites to implement. …
Short- and Long-term Outcomes After Continent Ileostomy: An Often Forgotten Option for Patients After Proctocolectomy
Publication Year: 2025 Source: Dis Colon Rectum PMID: 40192141 DOI: 10.1097/DCR.0000000000003720
BACKGROUND: Continent ileostomy is an alternative for reconstruction after proctocolectomy when IPAA is not feasible. Due to technical difficulties and patient preference, few centers still perform these operations. Recent literature focuses on ileostomies that are as old as 40 years, and there is a dearth of information on newly constructed …
A Risk Stratification Tool for Relapse After Intravenous-To-Subcutaneous Switching of Infliximab in Patients With Inflammatory Bowel Diseases
Publication Year: 2025 Source: Am J Gastroenterol PMID: 40192145 DOI: 10.14309/ajg.0000000000003466
INTRODUCTION: A subcutaneous formulation of infliximab was recently approved for maintenance therapy of inflammatory bowel disease (IBD). However, limited clinical experience, particularly with patients on escalated intravenous infliximab regimens, poses challenges for the transition to subcutaneous therapy. We investigated the pharmacokinetics and pharmacodynamics of subcutaneous infliximab to identify early predictors …
Risk of De Novo Inflammatory Bowel Disease in Patients With Psoriasis and Psoriatic Arthritis Treated With IL-17A Inhibitors: A Population-Based Study
Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 40192577 DOI: 10.1111/apt.70139
IL-17 inhibitors effectively treat psoriasis and psoriatic arthritis but may increase the risk of inflammatory bowel disease (IBD). We assessed their association with IBD compared to apremilast. Utilising the TriNetX database, we analysed patients with psoriasis or ankylosing spondylitis initiating IL-17 inhibitors or apremilast. We used propensity score matching and …
Lived Experiences of Patients With Inflammatory Bowel Disease in Italy: A Phenomenological Investigation
Publication Year: 2025 Source: Gastroenterol Nurs PMID: 40192751
Inflammatory bowel disease is a type of chronic gastrointestinal inflammatory disease. The chronic nature of the disease, the severity of its symptoms, and its unpredictability make it comparable to cancers regarding both its influence on quality of life and the direct and indirect health costs. The impact of inflammatory bowel …
Development of Hydrazide-Based HDAC6 Selective Inhibitors for Treating NLRP3 Inflammasome-Related Diseases
Publication Year: 2025 Source: J Med Chem PMID: 40193276
Previously, we found that hydrazide can serve as zinc binding groups for selective HDAC6 inhibitors and identified the first hydrazide-based HDAC6 inhibitor, 35m, which exhibited modest isoform selectivity. This study aimed to improve the HDAC6 selectivity of 35m, thereby reducing its side effects. Extensive structure-activity relationship studies revealed that the …
Need more literature?
The current database contains 98453 research articles. If you need to search for more literature or perform AI analysis, please use our knowledge acquisition module or explore external literature resources.
External Resources: Access comprehensive literature databases worldwide