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Effectiveness and Safety of Semaglutide for Weight Loss in Patients With Inflammatory Bowel Disease and Obesity

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 38642103 DOI: 10.1093/ibd/izae090

BACKGROUND: Semaglutide, a glucagon-like peptide-1 receptor agonist, has shown sustained and clinically significant weight loss in the general population. There are limited data on outcomes of its use in patients with inflammatory bowel disease (IBD). METHODS: A retrospective cohort study was conducted between June 4, 2021, and December 11, 2023, …

Severe Venous Calcifications in Phlebosclerotic Colitis and Significantly Decreased Expression in Betaine

Publication Year: 2025 Source: Int J Surg Pathol PMID: 38646813

No Abstract

Prospective Evaluation of the Prediction Score for a Mild Course of Crohn's Disease (PreMiCC) in Newly Diagnosed Patients With Crohn's Disease: The PROGNOS Study

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 38648264

BACKGROUND AND AIMS: The course of Crohn's disease (CD) is highly variable. The Prospektive Evaluation eines Score zur Vorhersage eines milden Verlaufsbei neu diagnostizierten Morbus Crohn-Patienten in gastroenterologischen Fachpraxen (PROGNOS) study aimed to determine the frequency of a mild disease course and validate a proposed prediction score. METHODS: The PROGNOS …

Efficacy of Dose Escalation of Oral 5-Aminosalicylic Acid for Ulcerative Colitis With a Mayo Endoscopic Subscore of 1: An Open Label Randomized Controlled Trial

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 38655866

BACKGROUND: Endoscopic healing is generally defined as Mayo endoscopic subscore (MES) </=1 in ulcerative colitis (UC). However, patients with an MES of 1 are at higher relapse risk than those with an MES of 0. This study evaluated the therapeutic efficacy of proactive dose escalation of oral 5-aminosalicylic acid (5-ASA) …

Ileorectal anastomosis in ulcerative colitis: what do surgeons and patients need to know? A systematic literature review

Publication Year: 2025 Source: Ann R Coll Surg Engl PMID: 38660816

No Abstract

The Multiple Roles of Heat Shock Proteins in the Development of Inflammatory Bowel Disease

Publication Year: 2025 Source: Curr Mol Med PMID: 38465431 DOI: 10.2174/0115665240286793240306053111

Inflammatory bowel disease (IBD), a chronic inflammatory condition of the human intestine, comprises Crohn's disease (CD) and ulcerative colitis (UC). IBD causes severe gastrointestinal symptoms and increases the risk of developing colorectal carcinoma. Although the etiology of IBD remains ambiguous, complex interactions between genetic predisposition, microbiota, epithelial barrier, and immune …

Protective effect of FKBP12 on dextran sulfate sodium-induced ulcerative colitis in mice as a tacrolimus receptor

Publication Year: 2025 Source: Nucleosides Nucleotides Nucleic Acids PMID: 38466901

No Abstract

Diffuse colonic capillary hemangioma mimicking ulcerative colitis

Publication Year: 2025 Source: Rev Esp Enferm Dig PMID: 38469795 DOI: 10.17235/reed.2024.10298/2024

Inflammatory bowel disease (IBD) diagnosis requires clinical, laboratory, endoscopic and histologic findings, and sometimes it can become a challenge. An exhaustive differential diagnosis with infectious disease, immunodeficiencies, hematologic, neoplastic, or vascular diseases must be made1, since prognosis and treatment vary depending on etiology. We present the case of a 62-year-old …

Syphilitic proctitis: review of the literature

Publication Year: 2025 Source: Rev Esp Enferm Dig PMID: 38469807

Syphilitic proctitis is a rare sexually transmitted disease caused by spirochete pallidum infecting the rectal mucosa. It usually has no specific clinical manifestations and is easily misdiagnosed with other rectal and anal diseases such as rectal cancer, malignant lymphoma, inflammatory bowel disease, etc.. Therefore, diagnosis of the disease is difficult …

Hyperbaric oxygen therapy for perianal Crohn's disease

Publication Year: 2025 Source: Rev Esp Enferm Dig PMID: 38469822

I read with great interest the letter by Calderon et al., who clearly described effectiveness of hyperbaric oxygen therapy (HBOT) for refractory ischemic ulcer at the ileorectal anastomosis in Crohn's disease (CD). I congratulate them on their efforts in achieving a favorable long-term outcome. I would like to share my …

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