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Ulcerative Colitis with Acute Pericarditis after Dose Escalation of Mesalazine

Publication Year: 2025 Source: Intern Med PMID: 39721687

No Abstract

Cannabis sativa alleviates experimentally acetic acid- induced ulcerative colitis in rats: targeting CB1/SIRT/MAPK signaling pathways

Publication Year: 2025 Source: Immunopharmacol Immunotoxicol PMID: 39721800 DOI: 10.1080/08923973.2024.2445733

BACKGROUND: Ulcerative colitis (UC) is a frequent inflammatory bowel disease (IBD) that causes long-lasting inflammation in the innermost lining of the rectum and colon. OBJECTIVE: The aim of this study was to evaluate the therapeutic effect of Cannabis sativa (C. sativa) on the amelioration of acetic acid-induced colitis in rats. …

An Oral H(2)S Responsive Cu(5.4)O Nanozyme Platform with Strong ROS/H(2)S Scavenging Capacity for the Treatment of Colitis

Publication Year: 2025 Source: ACS Appl Mater Interfaces PMID: 39722133

No Abstract

Oral Lactoferrin-Responsive Formulation Anchoring around Inflammatory Bowel Region for IBD Therapy

Publication Year: 2025 Source: Adv Healthc Mater PMID: 39722174 DOI: 10.1002/adhm.202402731

Oral formulation is the ideal treatment method for inflammatory bowel disease (IBD) therapy, but the mucosal damage and diarrhea symptoms impede the drug retention around the inflammatory region, severely limiting IBD therapeutic efficacy. To address this, an oral astaxanthin (Ast) precise delivery formulation is developed with the selective Ast anchoring …

Protective effects and mechanisms of extracts of Gleditsia sinensis Lam. Thorn on DSS-induced colitis in mice

Publication Year: 2025 Source: J Ethnopharmacol PMID: 39722326 DOI: 10.1016/j.jep.2024.119244

ETHNOPHARMACOLOGICAL RELEVANCE: Inflammatory Bowel Disease (IBD), encompassing Ulcerative Colitis (UC) and Crohn's Disease (CD), stems from a multifaceted interaction of hereditary, immunological, ecological, and microbial elements. Current treatments have limitations, necessitating new therapeutic approaches. AIM OF THE STUDY: This study investigates the safeguarding impacts and fundamental processes of extracts of …

Preliminary Evidence That Shared Genetic Influences Underlie Comorbidity Between Self-Reported Eating and Internalizing Disorders and Gastrointestinal Disease in Adult Women and Men

Publication Year: 2025 Source: Int J Eat Disord PMID: 39722530

No Abstract

Enhancing patient representation learning with inferred family pedigrees improves disease risk prediction

Publication Year: 2025 Source: J Am Med Inform Assoc PMID: 39723811

BACKGROUND: Machine learning and deep learning are powerful tools for analyzing electronic health records (EHRs) in healthcare research. Although family health history has been recognized as a major predictor for a wide spectrum of diseases, research has so far adopted a limited view of family relations, essentially treating patients as …

Therapeutic Drug Monitoring in Patients with Ulcerative Colitis on Infliximab: A Cost-Effectiveness Analysis

Publication Year: 2025 Source: Dig Dis Sci PMID: 39724469

No Abstract

Characteristics and Outcomes of Over a Million Patients with Inflammatory Bowel Disease in Seven Countries: Multinational Cohort Study and Open Data Resource

Publication Year: 2025 Source: Dig Dis Sci PMID: 39724470 DOI: 10.1007/s10620-024-08787-x

BACKGROUND AND AIMS: Observational healthcare data are an important tool for delineating patients' inflammatory bowel disease (IBD) journey in real-world settings. However, studies that characterize IBD cohorts typically rely on a single resource, apply diverse eligibility criteria, and extract variable sets of attributes, making comparison between cohorts challenging. We aim …

Chest CT Combined with Endoscopic Ultrasound Incision of the Mucosa and Removal of a Fish Bone (with Video)

Publication Year: 2025 Source: Dig Dis Sci PMID: 39725833 DOI: 10.1007/s10620-024-08806-x

No Abstract

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