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Higher Rates of Delay in Starting Advanced Inflammatory Bowel Disease Therapies Linked to Insurance Delays, Intravenous Infusions, and Lack of Pharmacy Support
Publication Year: 2025 Source: Clin Transl Gastroenterol PMID: 39718220
INTRODUCTION: Because biologic and small molecule therapy is expensive, payors have mandated preauthorizations for these medications, often resulting in a lengthy approval process. The aims of this study were to assess the frequency of and risk factors for delays in starting advanced therapies assessing insurance, care team, and patient-related factors. …
Preventive effect of Clostridium butyricum MIYAIRI against pouchitis in children with ulcerative colitis
Publication Year: 2025 Source: Surg Today PMID: 39718596
No Abstract
Gut-brain axis and neuroplasticity in health and disease: a systematic review
Publication Year: 2025 Source: Radiol Med PMID: 39718685
No Abstract
T lymphocyte plasticity in chronic inflammatory diseases: The emerging role of the Ikaros family as a key Th17-Treg switch
Publication Year: 2025 Source: Autoimmun Rev PMID: 39719186
No Abstract
Fucoxanthin ameliorates ulcerative colitis by maintaining the epithelial barrier via blocking JAK2/STAT3 signaling pathway
Publication Year: 2025 Source: Toxicol Appl Pharmacol PMID: 39719254
No Abstract
Acute Severe Ulcerative Colitis and Cytomegalovirus During Pregnancy: A Case Report
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39719680
No Abstract
The N-Acetyltransferase 2 Polymorphism and Susceptibility to Inflammatory Bowel Disease: A Case-Control Study
Publication Year: 2025 Source: Pharmacol Res Perspect PMID: 39720855 DOI: 10.1002/prp2.70040
The enzyme N-acetyltransferase 2 (NAT2) plays an important role in metabolism and detoxification of xenobiotics, including carcinogens and medications. We aimed to assess the contribution of the NAT2 polymorphism to susceptibility to inflammatory bowel disease (IBD) in the Polish population. The study involved 101 IBD patients and 100 healthy controls. …
Dietary Carrageenan Amplifies the Inflammatory Profile, but not Permeability, of Intestinal Epithelial Cells from Patients With Crohn's Disease
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39720875
BACKGROUND: The consumption of ultra-processed foods has increased significantly worldwide and is associated with the rise in inflammatory bowel diseases. However, any causative factors and their underlying mechanisms are yet to be identified. This study aimed to further elucidate whether different types of the dietary emulsifier carrageenan (CGN) can alter …
Exploring the causal inference of inflammatory bowel disease and ischemic stroke: a bidirectional two-sample Mendelian randomization study
Publication Year: 2025 Source: J Thromb Thrombolysis PMID: 39720960 DOI: 10.1007/s11239-024-03065-z
Growing evidence suggests inflammatory bowel disease (IBD) is linked to ischemic stroke (IS); however, the results are inconclusive. Therefore, it remains uncertain whether the association between IBD and IS is causal. Herein, we performed a bidirectional Mendelian randomization (MR) study to examine the causal association of IBD with IS. We …
20(S)-ginsenoside Rg3 alleviates DSS-induced colitis by promoting ERK-dependent maturation of MDSCs into M2 macrophages
Publication Year: 2025 Source: Biomed Pharmacother PMID: 39721327
No Abstract
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