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Novel targets for mucosal healing in inflammatory bowel disease therapy
Publication Year: 2025 Source: Int Immunopharmacol PMID: 39571265 DOI: 10.1016/j.intimp.2024.113544
Inflammatory bowel disease (IBD) is a chronic condition affecting the gastrointestinal tract, primarily manifesting as ulcerative colitis (UC) or Crohn's disease (CD). Both inflammation and disruption of the intestinal epithelial barrier are key factors in IBD pathogenesis. Substantial evidence has revealed a significant association between aberrant immune responses and impairment …
A Meta-Analysis of Proton Pump Inhibitor Exposure and the Risk of Adverse Outcomes in Patients with Inflammatory Bowel Disease
Publication Year: 2025 Source: Dig Dis PMID: 39571562 DOI: 10.1159/000542729
INTRODUCTION: This study aimed to investigate the association between proton pump inhibitors (PPIs) exposure and adverse outcomes in patients with inflammatory bowel disease (IBD). METHODS: According to the guidelines outlined in the PRISMA and Meta-analysis of Observational Studies in Epidemiology (MOOSE), we conducted a comprehensive search of PubMed, Web of …
Vedolizumab prophylaxis against postoperative Crohn's disease recurrence
Publication Year: 2025 Source: Lancet Gastroenterol Hepatol PMID: 39571586 DOI: 10.1016/S2468-1253(24)00352-2
No Abstract
Vedolizumab to prevent postoperative recurrence of Crohn's disease (REPREVIO): a multicentre, double-blind, randomised, placebo-controlled trial
Publication Year: 2025 Source: Lancet Gastroenterol Hepatol PMID: 39571587
No Abstract
The role of suppressor of cytokine signaling 3 in inflammatory bowel disease and its associated colorectal cancer
Publication Year: 2025 Source: Biochim Biophys Acta Mol Basis Dis PMID: 39571630 DOI: 10.1016/j.bbadis.2024.167578
Inflammatory bowel disease (IBD) and colorectal cancer (CRC), as two of the major human intestinal diseases, provide challenges for the medical field. Suppressor of cytokine signaling 3 (SOCS3), a protein molecule that negatively regulates cytokine signaling through multiple pathways, is involved in the regulation of various inflammatory diseases and tumors. …
Responsiveness of different disease activity indices in moderate-to-severe ulcerative colitis
Publication Year: 2025 Source: Med PMID: 39368474
No Abstract
Compound sophorae decoction mitigates DSS-induced ulcerative colitis by activating autophagy through PI3K-AKT pathway: A integrative research combining network pharmacology and in vivo animal model validation
Publication Year: 2025 Source: J Ethnopharmacol PMID: 39369920
No Abstract
Protective effects and mechanisms of HuDiChangRong capsule on TNBS-induced ulcerative colitis in mice
Publication Year: 2025 Source: J Ethnopharmacol PMID: 39369923
No Abstract
Increased Risk of Chronic Respiratory Disease among Individuals with Inflammatory Bowel Disease in a Prospective Cohort Study
Publication Year: 2025 Source: Am J Med PMID: 39370033
No Abstract
Unresectable Ulcerative Colitis Associated Colon Cancer in a Young Japanese Patient
Publication Year: 2025 Source: Intern Med PMID: 39370253
No Abstract
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