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Predicting Outcomes in Hospitalized Patients With Acute Severe Ulcerative Colitis in a Prospective Multicenter Cohort
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39418122
BACKGROUND AND AIMS: Acute severe ulcerative colitis (UC) (ASUC) requiring hospitalization affects up to 1 in 4 patients with UC. There is a paucity of prospective and multicenter clinical cohorts to study treatment trends and predictors of disease outcomes. Here, we conduct a US-based multicenter prospective clinical cohort of ASUC …
TOpClass Class 4 Perineal Crohn's Disease: A Systematic Review and Meta-analysis of Perineal Wound Complication After Proctectomy in Crohn's Patients
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39418126
BACKGROUND: Nonhealing perineal wounds have been reported to be common after proctectomy for Crohn's disease (CD). We performed a systematic review and meta-analysis of perineal wound healing after proctectomy for CD and assessed the risk factors for nonhealing. METHODS: A comprehensive literature search was conducted in PubMed, Embase, and Scopus …
Nonmalignant Dermatologic Disorders in Inflammatory Bowel Disease
Publication Year: 2025 Source: Am J Gastroenterol PMID: 39466220 DOI: 10.14309/ajg.0000000000003155
Inflammatory bowel disease (IBD) is associated with extraintestinal manifestations that can affect multiple body systems. Extraintestinal manifestations (EIMSs) are seen in up to 50% of patients with IBD. Skin involvement is particularly common occurring in up to 15%-20% of patients. Skin reactivity presents in multiple forms with unique pathology. Therapy …
Medical Therapies for Prevention and Treatment of Inflammatory Pouch Disorders-A Systematic Review and Meta-Analysis
Publication Year: 2025 Source: Am J Gastroenterol PMID: 39466277
No Abstract
Developing a Reproducible Radiomics Model for Diagnosis of Active Crohn's Disease on CT Enterography Across Annotation Variations and Acquisition Differences
Publication Year: 2025 Source: J Imaging Inform Med PMID: 39466507
No Abstract
That's Not a Hybrid: How to Distinguish Patterns of Admixture and Isolation By Distance
Publication Year: 2025 Source: Mol Ecol Resour PMID: 39467042 DOI: 10.1111/1755-0998.14039
Describing naturally occurring genetic variation is a fundamental goal of molecular phylogeography and population genetics. Popular methods for this task include STRUCTURE, a model-based algorithm that assigns individuals to genetic clusters, and principal component analysis (PCA), a parameter-free method. The ability of STRUCTURE to infer mixed ancestry makes it popular …
Autoimmune diseases and the risk and prognosis of latent autoimmune diabetes in adults
Publication Year: 2025 Source: Diabetologia PMID: 39467873
No Abstract
Evaluation of the Effectiveness and Safety of Mesenchymal Stem Cell Treatment in Fistulising Crohn's Disease: An International Real-Life Retrospective Multicentre Cohort Study
Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 39468719
No Abstract
XBB.1.5-Adapted COVID-19 mRNA Vaccines but Not Infections With Previous Omicron Variants Boost Neutralisation Against the SARS-CoV-2 JN.1 Variant in Patients With Inflammatory Bowel Disease
Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 39468971 DOI: 10.1111/apt.18349
BACKGROUND: Variant-adapted COVID-19 vaccines are recommended for patients with inflammatory bowel disease (IBD). However, many patients rely on pre-existing immunity by original vaccines or prior infections. AIM: To assess whether such immunity sufficiently combats the highly immune-evasive SARS-CoV-2 JN.1 variant. METHODS: Utilising two longitudinal cohorts, we evaluated immunity against JN.1 …
Quality of life of inflammatory bowel diseases patients in france with EQ-5D-5 L: the QALY-MICI study
Publication Year: 2025 Source: Qual Life Res PMID: 39470874 DOI: 10.1007/s11136-024-03821-x
PURPOSE: This study aimed to document utility values and the Visual Analog Scale (VAS) with the 5-level version of the EQ-5D questionnaire in a large sample of patients with inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). METHODS: QALY-MICI was a cross-sectional survey across three sources …
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