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The aqueous extract of Reynoutria japonica ameliorates damp-heat ulcerative colitis in mice by modulating gut microbiota and metabolism
Publication Year: 2025 Source: J Ethnopharmacol PMID: 39515678
No Abstract
Dermatoses in patients with inflammatory bowel disease under tumor necrosis factor-alpha inhibitors treatment
Publication Year: 2025 Source: Med Clin (Barc) PMID: 39516105 DOI: 10.1016/j.medcli.2024.09.004
INTRODUCTION: Tumor necrosis factor-alpha inhibitor (anti-TNF-alpha) agents are essential in treating inflammatory bowel diseases (IBD). Their use, however, may cause dermatoses. This study aims to characterize the dermatoses in IBD patients on anti-TNF-alpha therapy. METHODS: A total of 175 IBD patients, 105 (60%) on anti-TNF-alpha therapy were consecutively selected in …
Decursin protects against DSS-induced experimental colitis in mice by inhibiting the cGAS-STING signaling pathway
Publication Year: 2025 Source: Naunyn Schmiedebergs Arch Pharmacol PMID: 39520553 DOI: 10.1007/s00210-024-03589-4
While studies have shown that Angelica gigas Nakai (A. gigas) can alleviate ulcerative colitis in mice, the therapeutic role of its main active ingredient, decursin, is uncertain. Therefore, we aimed to investigate the protective effect and mechanism of decursin against inflammatory bowel disease (IBD) in vivo using mice. IBD was …
Analysis of the effectiveness and safety of maintenance treatment with intravenous ustekinumab in inflammatory bowel disease
Publication Year: 2025 Source: Rev Esp Enferm Dig PMID: 39629804
BACKGROUND AND PURPOSE: ustekinumab is a monoclonal antibody approved for the treatment of moderate to severe Crohn's disease (CD) and ulcerative colitis (UC). In spite of being an effective treatment, patients may have suboptimal response, or lose it over time. In these cases, ustekinumab intravenous (IV) maintenance therapy has been …
Impact of ustekinumab exposure on clinical outcomes during induction in inflammatory bowel disease
Publication Year: 2025 Source: Rev Esp Enferm Dig PMID: 39629805 DOI: 10.17235/reed.2024.10521/2024
BACKGROUND: understanding the relationship between ustekinumab (UST) exposure and clinical outcomes in inflammatory bowel disease (IBD) induction is crucial. However, evidence remains limited, highlighting the need to comprehend UST's pharmacokinetic variability for tailored treatments. AIMS: this study aimed to investigate the association between UST exposure during the induction phase and …
Faecal transplantation: the good, the bad and the ugly
Publication Year: 2025 Source: Intern Med J PMID: 39629909
No Abstract
Correction to: Deep learning-based reconstruction improves the image quality of low-dose CT enterography in patients with inflammatory bowel disease
Publication Year: 2025 Source: Abdom Radiol (NY) PMID: 39630201
No Abstract
Axial Spondyloarthritis: A Review
Publication Year: 2025 Source: JAMA PMID: 39630439
IMPORTANCE: Axial spondyloarthritis is an immune-mediated inflammatory condition involving the sacroiliac joints, spine, and peripheral joints. It affects approximately 1% of adults in the US and is associated with impaired physical function and reduced quality of life. OBSERVATIONS: Inflammatory chronic back pain characterized by gradual onset starting before age 45 …
Preparation, Characterization, and In Vitro Evaluation of Chlorogenic Acid Loaded Hydrogel Beads for the Management of Ulcerative Colitis
Publication Year: 2025 Source: Assay Drug Dev Technol PMID: 39630502
No Abstract
Idiopathic encapsulating peritoneal sclerosis: A case report
Publication Year: 2025 Source: Int J Surg Case Rep PMID: 39631118
No Abstract
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