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Retinoblastoma-binding Protein 9 Suppresses Intestinal Inflammation and Inflammation-induced Tumorigenesis in Mice
Publication Year: 2025 Source: Cell Mol Gastroenterol Hepatol PMID: 39631567
No Abstract
Probiotic Bacillus cereus regulates metabolic disorders and activates the cholic acid-FXR axis to alleviate DSS-induced colitis
Publication Year: 2025 Source: J Proteomics PMID: 39631667 DOI: 10.1016/j.jprot.2024.105360
Inflammatory bowel disease is characterized by severe imbalance of intestinal flora and metabolic disorders. Recent studies have demonstrated that probiotics can effectively alleviate inflammatory bowel disease by restoring the intestinal flora structure and modulating the immune response. However, the role of probiotics in regulating intestinal metabolism disorders is still unclear. …
Aseptic Abscess of the Gallbladder Mimicking Gallbladder Carcinoma after Surgery for Ulcerative Colitis
Publication Year: 2025 Source: Intern Med PMID: 39631865
No Abstract
Model-informed precision dosing in inflammatory bowel diseases
Publication Year: 2025 Source: Trends Pharmacol Sci PMID: 39632196 DOI: 10.1016/j.tips.2024.11.003
Therapeutic drug monitoring (TDM) for biologic therapies in inflammatory bowel disease (IBD) primarily aims to optimize dosing. However, several unmet needs remain. These include the identification of optimal drug concentrations, accounting for variability in pharmacokinetics (PK) and pharmacodynamics (PD), and the frequent delays between sampling and clinical decision-making. Recent technical …
Towards a Greener IBD-Care: Let's INTERACT!
Publication Year: 2025 Source: United European Gastroenterol J PMID: 39632541 DOI: 10.1002/ueg2.12728
No Abstract
Mucosal Healing in Inflammatory Bowel Diseases: Still Too Many Irons on the Fire. Authors' Reply
Publication Year: 2025 Source: United European Gastroenterol J PMID: 39632545
No Abstract
Needle or Drip?-Real-World Comparison of Intravenous to Subcutaneous Infliximab and Vedolizumab in the Management of Inflammatory Bowel Diseases
Publication Year: 2025 Source: Dig Dis Sci PMID: 39633231
No Abstract
Case report: lichen planus in a patient with ulcerative colitis receiving sulfasalazine: a drug effect or a disease manifestation?
Publication Year: 2025 Source: Future Sci OA PMID: 39633238
No Abstract
Advances in colon-targeted drug technologies
Publication Year: 2025 Source: Curr Opin Gastroenterol PMID: 39633585 DOI: 10.1097/MOG.0000000000001064
PURPOSE OF REVIEW: Herein, we present an overview of innovative oral technologies utilized in colonic drug delivery systems that have made significant translational and clinical advancements to treat inflammatory bowel disease (IBD) in recent years. RECENT FINDINGS: The colon is home to distinct physiological conditions, such as pH and microbiota, …
Clinical Characteristics, Management, and Outcomes of Colitis-Associated Colorectal Cancer and the Comparison With Sporadic Colorectal Cancer in Taiwan
Publication Year: 2025 Source: Clin Transl Gastroenterol PMID: 39636008
INTRODUCTION: We explored the clinical characteristics, treatment, and outcomes of colitis-associated colorectal cancer (CAC) and compared with sporadic colorectal cancer in Taiwan. METHODS: In this retrospective study spanning 1987-2022, CACs diagnosed according to endoscopic and pathological reports from 14 tertiary centers were reported to our cohort. Clinical demographics, endoscopic findings, …
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