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Oral chitosan-cyclodextrin "shell-core" nanoparticles co-loaded Rhein and chlorogenic acid for ulcerative colitis treatment
Publication Year: 2025 Source: Int J Biol Macromol PMID: 39647762
No Abstract
Versatile inulin/trans-ferulic acid/silk sericin nanoparticles-nourished probiotic complex with prolonged intestinal retention for synergistic therapy of inflammatory bowel disease
Publication Year: 2025 Source: Carbohydr Polym PMID: 39647933 DOI: 10.1016/j.carbpol.2024.123063
To achieve effective long-term synergistic treatment of inflammatory bowel disease (IBD) with probiotics, we developed a versatile inulin/trans-ferulic acid/silk sericin nanoparticles-nourished probiotic complex. Inulin/TFA/SS nanoparticles were fabricated by inulin, trans-ferulic acid (TFA), and silk sericin (SS), and then loaded onto the surface of poly-l-lysine (PLL) and poly-glutamic acid (PGA)-coated Bifidobacterium …
Impact of Chronic Inflammatory Diseases on Clinical Pharmacokinetics of Antibody-Based Therapeutic Proteins
Publication Year: 2025 Source: Clin Pharmacol Ther PMID: 39648593
No Abstract
Serum Neutrophil Biomarkers to Predict Crohn's Disease Progression and Infliximab Treatment Outcomes
Publication Year: 2025 Source: United European Gastroenterol J PMID: 39648597
No Abstract
The Role of Antibiotic Exposure as a Risk Factor for IBD Epidemic: An Updated Meta-Analysis
Publication Year: 2025 Source: J Gastroenterol Hepatol PMID: 39648624 DOI: 10.1111/jgh.16845
No Abstract
Integrated Microbiome and Metabolomic to Explore the Mechanism of Coptisine in Alleviating Ulcerative Colitis
Publication Year: 2025 Source: Phytother Res PMID: 39648789
No Abstract
A decade of real-world clinical experience with 8-week azithromycin-metronidazole combined therapy in paediatric Crohn's disease
Publication Year: 2025 Source: J Pediatr Gastroenterol Nutr PMID: 39648957
No Abstract
IgG4 in the gut: Gastrointestinal IgG4-related disease or a new subtype of inflammatory bowel disease
Publication Year: 2025 Source: Autoimmun Rev PMID: 39653260 DOI: 10.1016/j.autrev.2024.103720
IgG4-related disease (IgG4-RD) is a chronic inflammatory condition characterized by tissue infiltration with IgG4-positive plasma cells, leading to fibrosis and organ dysfunction. While primarily affecting the pancreas, bile ducts, and salivary glands, IgG4-RD can also involve the gastrointestinal tract, raising questions about its relationship with inflammatory bowel disease (IBD). Recent …
Clinically relevant cell culture model of inflammatory bowel diseases for identification of new therapeutic approaches
Publication Year: 2025 Source: Int J Pharm PMID: 39653295 DOI: 10.1016/j.ijpharm.2024.125062
Inflammatory Bowel Diseases (IDB) are chronic disorders characterized by gut inflammation, mucosal damage, increased epithelial permeability and altered mucus layer. No accurate in vitro model exists to simulate these characteristics. In this context, drug development for IBD or intestinal inflammation requires in vivo evaluations to verify treatments efficacy. A new …
The Impact of Smoking on Ulcerative Colitis and Interaction With Family History: A Population-Based Cohort Study
Publication Year: 2025 Source: J Gastroenterol Hepatol PMID: 39654516
No Abstract
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