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Endoscopic diagnosis and management of adult inflammatory bowel disease: a consensus document from the American Society for Gastrointestinal Endoscopy IBD Endoscopy Consensus Panel
Publication Year: 2025 Source: Gastrointest Endosc PMID: 39425706 DOI: 10.1016/j.gie.2024.08.034
Endoscopy plays a key role in diagnosis, monitoring of disease activity, assessment of treatment response, dysplasia surveillance, postoperative evaluation, and interventional therapy for patients with inflammatory bowel disease (IBD). Clinical practice patterns in the endoscopic management of IBD vary. A panel of experts consisting of IBD specialists, endoscopists, and GI …
Impact of pain, fatigue and bowel incontinence on the quality of life of people living with inflammatory bowel disease: A UK cross-sectional survey
Publication Year: 2025 Source: United European Gastroenterol J PMID: 39425758 DOI: 10.1002/ueg2.12668
BACKGROUND AND AIMS: People with inflammatory bowel disease (IBD) often experience pain, fatigue and bowel incontinence and are at an increased risk of anxiety and depression. Our aim was to assess the impact of these symptoms on health-related quality of life (QoL) in IBD. METHODS: In the IBD-BOOST survey, over …
Macrophage-Derived Exosomes Promoted the Development and Stemness of Inflammatory Bowel Disease-Related Colorectal Cancer via nuclear paraspeckle assembly transcript 1-Mediated miRNA-34a-5p/phosphoprotein enriched in astrocytes 15 Axis
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39425913 DOI: 10.1093/ibd/izae212
BACKGROUND: Inflammatory bowel disease (IBD) is closely associated with the development of colorectal cancer (CRC) due to the chronic inflammatory response. Macrophages play critical roles in regulating the microenvironment to facilitate tumor progression. Exosomes are key modulators for the communication between macrophages and tumor cells. The mechanism of macrophage-derived exosomes …
A novel, portable, and cost-effective turbidimetric sensor for sensitive alkaline phosphatase activity assay
Publication Year: 2025 Source: Biosens Bioelectron PMID: 39426277
No Abstract
Gut Goo: Physiology, Diet, and Therapy of Intestinal Mucus and Biofilms in Gastrointestinal Health and Disease
Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 39426645
No Abstract
Shaoyao decoction alleviates DSS-induced colitis by inhibiting IL-17a-mediated polarization of M1 macrophages
Publication Year: 2025 Source: J Ethnopharmacol PMID: 39427735
No Abstract
Bile acids as signaling molecules in inflammatory bowel disease: Implications for treatment strategies
Publication Year: 2025 Source: J Ethnopharmacol PMID: 39427739 DOI: 10.1016/j.jep.2024.118968
ETHNOPHARMACOLOGICAL RELEVANCE: Inflammatory bowel disease (IBD) is a globally increasing disease. Despite continuous efforts, the clinical application of treatment drugs has not achieved satisfactory success and faces limitations such as adverse drug reactions. Numerous investigations have found that the pathogenesis of IBD is connected with disturbances in bile acid circulation …
RGS10 Deficiency Alleviated Intestinal Mucosal Inflammation Through Suppression of Th1/Th17 Cell Immune Responses in Ulcerative Colitis
Publication Year: 2025 Source: Immunology PMID: 39428350
No Abstract
Association between Clinical Characteristics and Sarcopenia or Sarcopenic Obesity in Crohn's Disease
Publication Year: 2025 Source: Intern Med PMID: 39428526
No Abstract
Pregnancy zone protein, a potential research target in multiple diseases
Publication Year: 2025 Source: Gene PMID: 39433266 DOI: 10.1016/j.gene.2024.149013
Pregnancy zone protein (PZP) is an antiprotease-resistant immunosuppressant belonging to the alpha-macroglobulin (alphaM) protein family. PZP is secreted by the liver and was found to be upregulated in plasma during pregnancy. alpha-2-macroglobulin (Alpha2M) shares 71 % serial homology with PZP, but low PZP levels do not lead to increased A2M …
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