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Comparative Efficacy and Safety of Three Janus Kinase Inhibitors in Ulcerative Colitis: A Real-World Multicentre Study in Japan
Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 39578704
No Abstract
Iron Deficiency Anemia in Patients with Inflammatory Bowel Disease: A Call to Action to Improve Patient Care
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39579077
No Abstract
Protective effect of Dulaglutide, a GLP1 agonist, on acetic acid-induced ulcerative colitis in rats: involvement of GLP-1, TFF-3, and TGF-β/PI3K/NF-κB signaling pathway
Publication Year: 2025 Source: Naunyn Schmiedebergs Arch Pharmacol PMID: 39579211
No Abstract
Enhancing Epstein-Barr virus detection in IBD patients with XAI and clinical data integration
Publication Year: 2025 Source: Comput Biol Med PMID: 39579664 DOI: 10.1016/j.compbiomed.2024.109465
BACKGROUND: There is increasing evidence of a link between Epstein-Barr virus (EBV) and gastrointestinal cancers, particularly in immunocompromised patients and those on thiopurines. Traditional endoscopic techniques have limitations in diagnosing EBV, whereas standard methods for diagnosing EBV have practical challenges in regular clinical settings related to their invasiveness and high …
VRK2 inhibits the replication of infectious bursal disease virus by phosphorylating RACK1 and suppressing apoptosis
Publication Year: 2025 Source: Int J Biol Macromol PMID: 39579830 DOI: 10.1016/j.ijbiomac.2024.137940
Infectious bursal disease (IBD) is an acute, highly contagious, and immunosuppressive avian disease caused by the infectious bursal disease virus (IBDV). Despite significant efforts, the lack of knowledge about host proteins that counteract IBDV replication has hindered progress in preventing and controlling IBD in chickens. This study identifies the mitochondria-associated …
Mendelian randomization and genetic pleiotropy analysis for the connection between inflammatory bowel disease and Alzheimer's disease
Publication Year: 2025 Source: Prog Neuropsychopharmacol Biol Psychiatry PMID: 39579960 DOI: 10.1016/j.pnpbp.2024.111203
BACKGROUND: The gut-microbiome-brain axis (GMBA) implies the connection between inflammatory bowel disease (IBD) and Alzheimer's disease (AD). We aimed to comprehensively explore the relation between IBD (and its subtypes) and AD, early-onset AD (EOAD) and late-onset AD (LOAD) from a genetic pleiotropy perspective. METHODS: Relying on summary statistics (N = …
Abdominal ultrasound stimulation alleviates DSS-induced colitis and behavioral disorders in mice by mediating the microbiota-gut-brain axis balance
Publication Year: 2025 Source: Neurotherapeutics PMID: 39580323 DOI: 10.1016/j.neurot.2024.e00494
Inflammatory bowel disease (IBD) has the potential to induce neuroinflammation, which may increase the risk of developing neurodegenerative disorders. Ultrasound stimulation to the abdomen is a potential treatment for dextran sulfate sodium (DSS)-induced acute colitis. The present study aimed to investigate whether abdominal low-intensity pulsed ultrasound (LIPUS) can alleviate DSS-induced …
Research progress on anti-inflammatory drugs for preventing colitis-associated colorectal cancer
Publication Year: 2025 Source: Int Immunopharmacol PMID: 39580861 DOI: 10.1016/j.intimp.2024.113583
Colorectal cancer (CRC) is the third most prevalent malignancy worldwide. Inflammatory bowel diseases (IBD) encompass a group of chronic intestinal inflammatory disorders, including ulcerative colitis (UC) and Crohn's disease (CD). As a chronic inflammatory bowel disease, UC may persist and elevate the risk of malignancy, thereby contributing to the development …
Fecal fatty acid-linked bile acid profiles in pediatric patients with ulcerative colitis
Publication Year: 2025 Source: Clin Chim Acta PMID: 39581249
No Abstract
Inflammatory bowel disease in the gypsy community in England and Scotland
Publication Year: 2025 Source: Gastroenterol Hepatol PMID: 39581375
No Abstract
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