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LINE-1 hypomethylation characterizes the inflammatory response in coeliac disease associated-intestinal mucosa and small bowel adenocarcinomas

Publication Year: 2025 Source: J Pathol PMID: 39601242

No Abstract

Editorial: Allostatic Load and Inflammatory Bowel Disease

Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 39601634

No Abstract

Editorial: Allostatic Load and Inflammatory Bowel Disease. Authors' Reply

Publication Year: 2025 Source: Aliment Pharmacol Ther PMID: 39601635

No Abstract

Knowledge, Values, and Preferences Regarding Contraceptive Choices Among Women Living With Inflammatory Bowel Disease

Publication Year: 2025 Source: J Crohns Colitis PMID: 39602552 DOI: 10.1093/ecco-jcc/jjae181

BACKGROUND AND AIMS: Active inflammatory bowel disease (IBD) at conception is associated with adverse pregnancy outcomes. International guidelines address antenatal care, but contraception counseling and risk assessment are not addressed. Data on healthcare professionals' guidance for women with IBD regarding contraception are scarce. We aimed to describe contraceptive use, preferences, …

Development of an Automated Tool for the Estimation of Histological Remission in Ulcerative Colitis Using Single-Wavelength Endoscopy Technology

Publication Year: 2025 Source: J Crohns Colitis PMID: 39602814

BACKGROUND AND AIMS: Ulcerative colitis (UC) management employs a strategy targeting histological and endoscopic remission. Correlation of white light endoscopy (WLE) scores with histological activity is limited. Single-wavelength endoscopy (SWE), addressing microvascular changes reflecting histological disease activity, may better assess histological remission. Our goal was to assess the accuracy of …

Evaluation of the Effect of Probiotic Supplementation on Intestinal Barrier Integrity and Epithelial Damage in Colitis Disease: A Systematic Review

Publication Year: 2025 Source: Nutr Rev PMID: 39602817

CONTEXT: Previous reviews have focused on the effects of probiotics on colitis, but there is a need to understand their impact on barrier integrity and tight junction protein improvement in colitis. OBJECTIVE: This study aimed to systematically examine the effects of probiotic use on barrier integrity in colitis disease. This …

Does Atopic Dermatitis Increase the Risk of Inflammatory Bowel Disease? A Meta-Analysis of Data from 61 Million Participants

Publication Year: 2025 Source: Int Arch Allergy Immunol PMID: 39602916 DOI: 10.1159/000542777

INTRODUCTION: This review aimed to examine if atopic dermatitis (AD) led to an increased risk of inflammatory bowel disease (IBD) by collating data from longitudinal studies. METHODS: Cohort and case-control studies examining the risk of IBD, Crohn's disease (CD), or ulcerative colitis (UC) due to exposure to AD were included …

Design, synthesis, and evaluation of quinolin-2(1H)-ones as PDE1 inhibitors for the treatment of inflammatory bowel disease

Publication Year: 2025 Source: Bioorg Chem PMID: 39603073 DOI: 10.1016/j.bioorg.2024.107979

Inflammatory bowel disease (IBD) is a chronic inflammatory disease that affects the entire gastrointestinal tract. The complex etiology of IBD made it difficult to cure. Phosphodiesterases (PDEs) have garnered significant attention due to their involvement in immune and inflammatory responses in IBD. Most recently, we have reported a novel PDE1 …

Luteolin modulates macrophage phenotypic switching via the AMPK-PPARγ pathway to alleviate ulcerative colitis in mice

Publication Year: 2025 Source: J Ethnopharmacol PMID: 39603400

No Abstract

Eco-gastroenterology in Inflammatory Bowel Disease Treatment: A Call for Sustainable Healthcare

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39603831

No Abstract

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