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Vonoprazan as a Long-term Maintenance Treatment for Erosive Esophagitis: VISION, a 5-Year, Randomized, Open-label Study

Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 39209187

No Abstract

Systematic Review and Meta-analysis: The Three-year Post-colonoscopy Colorectal Cancer Rate as per the World Endoscopy Organization Methodology

Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 39209191

No Abstract

Early Biological Therapy Within 12 Months of Diagnosis Leads to Higher Transmural Healing Rates in Crohn's Disease

Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 39209193

No Abstract

Thiopurines and the Risk of Cancer in Patients With Inflammatory Bowel Disease and Reference Individuals Without Inflammatory Bowel Disease: A Danish Nationwide Cohort Study (1996-2018)

Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 39209201 DOI: 10.1016/j.cgh.2024.08.006

BACKGROUND & AIMS: Thiopurine therapy is a cornerstone in the treatment of inflammatory bowel disease (IBD). We aimed to assess the effect of thiopurines on cancer risk in IBD according to drug exposure and age. METHODS: Danish national registers were used to identify incident IBD patients, exposure to drugs, and …

Epidemiology of Elderly Onset IBD: A Nationwide Population-Based Cohort Study

Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 39209204 DOI: 10.1016/j.cgh.2024.08.011

BACKGROUND AND AIMS: We examined the incidence and natural history of patients with very elderly onset (herein referred to as very late-onset) inflammatory bowel diseases (IBDs) (>/= 70 years of age at diagnosis), compared with patients diagnosed between 60 and 69 years of age in Denmark. METHODS: In the Danish …

Impact of Clinical Pharmacists in the Inflammatory Bowel Disease Clinic

Publication Year: 2025 Source: J Pharm Pract PMID: 39032170 DOI: 10.1177/08971900241264339

Background: Limited evidence exists regarding pharmacist involvement and impact in inflammatory bowel disease (IBD) interdisciplinary clinic care models. The purpose is to describe pharmacist utilization in an interdisciplinary IBD clinic and evaluate clinical impact on patient quality of life. Methods: This was a retrospective cohort study comparing outcomes in patients …

Risk of avascular necrosis in patients with inflammatory bowel disease: Insights from a nationwide cohort study and the impact of corticosteroid use

Publication Year: 2025 Source: Dig Liver Dis PMID: 39033076 DOI: 10.1016/j.dld.2024.07.006

BACKGROUND AND AIM: Corticosteroid use is a risk factor for avascular necrosis (AVN) and inflammatory bowel disease (IBD) patients are often exposed to higher corticosteroid usage. We investigated the epidemiology and risk factors of AVN in a nationwide population-based cohort of IBD patients. METHODS: Patients newly diagnosed with IBD were …

Risankizumab Is Effective for The Management of Crohn's Disease of the Pouch

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39038228

No Abstract

The Natural History of Crohn's Disease Leading to Intestinal Failure: A Longitudinal Cohort Study from 1973 to 2018

Publication Year: 2025 Source: J Crohns Colitis PMID: 39039902

BACKGROUND AND AIMS: The natural history of Crohn's disease leading to intestinal failure is not well characterised. This study aims to describe the clinical course of Crohn's disease preceding intestinal failure and to compare disease course and burden between Crohn's disease patients with and without intestinal failure. METHODS: Patients with …

A Bottom-Up Liquid Chromatography-Tandem Mass Spectrometry Method for Therapeutic Drug Monitoring of Infliximab: Method Development, Comparison With 2 Enzyme-Linked Immunosorbent Assay Methods, and Evaluation of Anti-Drug Antibody Interference

Publication Year: 2025 Source: Arch Pathol Lab Med PMID: 39041105

CONTEXT.-: Therapeutic drug monitoring is recommended to optimize infliximab use and improve outcome in chronic inflammatory disorders. OBJECTIVE.-: To describe a simple and affordable liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to measure in fl iximab in serum. DESIGN.-: Infliximab was measured using winged stable isotope-labeled peptides as internal standards. Linearity, …

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