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Introducing the Arabic inflammatory bowel disease disk as a tool for assessing disability in patients with inflammatory bowel disease in Jordan
Publication Year: 2025 Source: Arab J Gastroenterol PMID: 39277517 DOI: 10.1016/j.ajg.2024.01.011
BACKGROUND AND STUDY AIM: Inflammatory bowel diseases (IBD) are chronic relapsing-remitting disorders of the gastrointestinal tract. IBD causes significant impairment in the patient's quality of life that should be assessed and monitored in a flexible and easy way. The IBD-Disability Index (IBD-DI) is the only validated tool to assess disability …
Prenatal cannabis exposure is associated with alterations in offspring DNA methylation at genes involved in neurodevelopment, across the life course
Publication Year: 2025 Source: Mol Psychiatry PMID: 39277688
No Abstract
A high cholesterol diet aggravates experimental colitis through SREBP2-modulated endocytosis and degradation of occludin and Zo-1 proteins
Publication Year: 2025 Source: FEBS J PMID: 39279038 DOI: 10.1111/febs.17269
No Abstract
Letter: Change in Bowel Urgency in Active Ulcerative Colitis Patients Treated with Curcumin-QingDai (CurQD): A Post Hoc Analysis of a Randomized Placebo-Controlled Trial
Publication Year: 2025 Source: J Crohns Colitis PMID: 39279191
No Abstract
Oxidized Polyunsaturated Fatty Acid Promotes Colitis and Colitis-Associated Tumorigenesis in Mice
Publication Year: 2025 Source: J Crohns Colitis PMID: 39279209 DOI: 10.1093/ecco-jcc/jjae148
BACKGROUND AND AIMS: Human studies suggest that a high intake of polyunsaturated fatty acid (PUFA) is associated with an increased risk of inflammatory bowel disease (IBD). PUFA is highly prone to oxidation. To date, it is unclear whether unoxidized or oxidized PUFA is involved in the development of IBD. Here, …
Pioglitazone as a potential modulator in autoimmune diseases: a review on its effects in systemic lupus erythematosus, psoriasis, inflammatory bowel disease, and multiple sclerosis
Publication Year: 2025 Source: Expert Rev Clin Immunol PMID: 39279585
No Abstract
Impact of magnesium on intraperitoneal adhesion in an experimental rat model
Publication Year: 2025 Source: Adv Clin Exp Med PMID: 39283682
BACKGROUND: Intraperitoneal adhesions are fibrous bands that form between tissues and organs in the abdominal cavity, which can result from the body's healing process after surgery, leading to pain, bowel obstruction, and infertility in severe cases. Magnesium (Mg), known for its anti-inflammatory and anticoagulant properties, has been hypothesized to influence …
Deployment of an Artificial Intelligence Histology Tool to Aid Qualitative Assessment of Histopathology Using the Nancy Histopathology Index in Ulcerative Colitis
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39284932
BACKGROUND: Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by increased stool frequency, rectal bleeding, and urgency. To streamline the quantitative assessment of histopathology using the Nancy Index in UC patients, we developed a novel artificial intelligence (AI) tool based on deep learning and tested it in a …
Resolution of Severe Ulcerative Colitis Secondary to Nickel Allergy Following Explantation of Amplatzer Septal Occluder Device: A Delayed Presentation
Publication Year: 2025 Source: World J Pediatr Congenit Heart Surg PMID: 39285815
No Abstract
Closed-loop theranostic microgels for immune microenvironment modulation and microbiota remodeling in ulcerative colitis
Publication Year: 2025 Source: Biomaterials PMID: 39288617 DOI: 10.1016/j.biomaterials.2024.122834
Inflammatory bowel disease (IBD) is characterized by the upregulation of reactive oxygen species (ROS) and dysfunction of gut immune system, and microbiota. The conventional treatments mainly focus on symptom control with medication by overuse of drugs. There is an urgent need to develop a closed-loop strategy that combines in situ …
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