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Disease prevention trials in IBD: feasibility to future outlook

Publication Year: 2025 Source: Nat Rev Gastroenterol Hepatol PMID: 39304774 DOI: 10.1038/s41575-024-00984-3

No Abstract

Preventing Post-Colonoscopy Colorectal Cancer in Inflammatory Bowel Disease-"The Big Five"

Publication Year: 2025 Source: J Crohns Colitis PMID: 39305189

No Abstract

Thromboembolic phenomena in inflammatory bowel disease and risk with JAK inhibitor treatments

Publication Year: 2025 Source: Gastroenterol Hepatol PMID: 39306076

No Abstract

Etrasimod Corticosteroid-Free Efficacy, Impact of Concomitant Corticosteroids on Efficacy and Safety, and Corticosteroid-Sparing Effect in Ulcerative Colitis: Analyses of the ELEVATE UC Clinical Program

Publication Year: 2025 Source: J Crohns Colitis PMID: 39306680

BACKGROUND: Etrasimod is an oral, once-daily, selective sphingosine 1-phosphate (S1P)1,4,5 receptor modulator for the treatment of moderately to severely active ulcerative colitis (UC). This post hoc analysis reports the efficacy and safety of etrasimod based on baseline corticosteroid (CS) use in the ELEVATE UC clinical program. METHODS: Patients with UC …

Differentiating clinical characteristics of perianal inflammatory bowel disease from perianal hidradenitis suppurativa

Publication Year: 2025 Source: Int J Dermatol PMID: 39306801 DOI: 10.1111/ijd.17498

BACKGROUND: Perianal draining tunnels in hidradenitis suppurativa (HS) and perianal fistulizing inflammatory bowel disease (IBD) present diagnostic and management dilemmas. METHODS: We conducted a retrospective chart review of patients with perianal disease evaluated at Mayo Clinic from January 1, 1998, through July 31, 2021. Patients' demographic and clinical data were …

Anatomical Suitability of Iliac Branch Devices for East Asian Patients with Abdominal Aortic Aneurysm

Publication Year: 2025 Source: Eur J Vasc Endovasc Surg PMID: 39307231 DOI: 10.1016/j.ejvs.2024.09.024

OBJECTIVE: This study aimed to identify the iliac artery characteristics of East Asian patients with abdominal aortic aneurysms (AAAs) and to evaluate anatomical suitability rates with current iliac branch devices (IBDs). METHODS: This was a single centre, retrospective, cross sectional study. Patients diagnosed with AAA between 2008 and 2023 were …

Effectiveness, safety, and cost of combination advanced therapies in inflammatory bowel disease

Publication Year: 2025 Source: Dig Liver Dis PMID: 39307602 DOI: 10.1016/j.dld.2024.08.055

BACKGROUND: A significant proportion of inflammatory bowel disease (IBD) patients fail to respond to advanced therapies. Combining advanced therapies may improve treatment outcome. This study aimed to assess the effectiveness, adverse events, and costs associated with combining advanced therapies in IBD patients. METHODS: Combination advanced therapy was defined as the …

Remote monitoring after elective colorectal surgery, a pilot study

Publication Year: 2025 Source: Surgery PMID: 39307673

No Abstract

PET/MRI in paediatric inflammatory bowel disease - a prospective accuracy study

Publication Year: 2025 Source: Clin Physiol Funct Imaging PMID: 39308430 DOI: 10.1111/cpf.12903

Cross-sectional imaging supplements endoscopy in detecting disease manifestations in inflammatory bowel diseases (IBD). This study aimed to evaluate the accuracy of PET/MRI in a paediatric population suspected of IBD. This prospective study consecutively included patients aged 8-17 years under diagnostic evaluation for IBD. Forty-three patients underwent a PET/MRI scan and …

Long-Term Outcomes of Intravenous Ustekinumab Maintenance Treatment in Patients With Loss of Response to Subcutaneous Dosing

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39082955

BACKGROUND: Ustekinumab (UST) is commonly used to treat Crohn's disease and ulcerative colitis. However, some patients may experience diminishing response or require increased dosage. Intravenous (IV) UST maintenance is explored as a solution. OBJECTIVES: We sought to evaluate IV UST maintenance effectiveness and safety in inflammatory bowel disease patients with …

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