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Mucosal and Transmural Healing and Long-term Outcomes in Crohn's Disease

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39083264

BACKGROUND: Healing in Crohn's disease is complex and difficult to measure due to incongruencies between clinical symptoms and disease states. Mucosal healing (MH) and transmural healing (TH) are increasingly used to measure clinical improvement in Crohn's disease, but definitions of MH and TH can vary across studies, and their relationship …

Effect of Overweight and Obesity on the Response to Anti-TNF Therapy and Disease Course in Children With IBD

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39083286 DOI: 10.1093/ibd/izae165

BACKGROUND: This study aimed to evaluate the effect of overweight and obesity at the start of anti-TNF therapy on treatment response and relapse rate in children with inflammatory bowel disease (IBD). METHODS: This multicenter, retrospective cohort study included 22 IBD centers in 14 countries. Children diagnosed with IBD in whom …

The Utility of Intestinal Ultrasound in a Case of Microscopic Colitis

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39083291

No Abstract

Live Rotavirus Vaccination Appears Low-risk in Infants Born to Mothers With Inflammatory Bowel Disease on Biologics

Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 39089515

No Abstract

Endoscopic, Histologic, and Composite Endpoints in Patients With Ulcerative Colitis Treated With Etrasimod

Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 39089519

No Abstract

Risk of developing IBD in high-risk individuals: the need to study the exposome more

Publication Year: 2025 Source: Gut PMID: 39089859 DOI: 10.1136/gutjnl-2024-333347

No Abstract

The etiological profile of chronic organic non-bloody diarrhea in India: Emergence of inflammatory bowel disease as a dominant cause

Publication Year: 2025 Source: Indian J Gastroenterol PMID: 39093512 DOI: 10.1007/s12664-024-01649-4

BACKGROUND: Chronic non-bloody diarrhea may be attributed either to functional or organic diseases. The latter category may present with malabsorption syndrome if there is extensive involvement of the small bowel, whereas diseases of the large bowel may only present with diarrhea sans malabsorption. Indian data has predominantly focussed on the …

Sample comparison of BÜHLMANN fCAL Turbo and OC-FCa faecal calprotectin methods

Publication Year: 2025 Source: Ann Clin Biochem PMID: 39093620 DOI: 10.1177/00045632241273266

BACKGROUND: Faecal calprotectin is an inflammatory marker used to triage patients for further investigation with suspected inflammatory bowel disease (IBD). Our current method requires faecal samples be sent to the laboratory, where calprotectin is extracted before analysis. This is a time-consuming, potential bottleneck in the pathway. We have recently evaluated …

Mirikizumab Sustained Impact on Fatigue in Patients with Moderately to Severely Active Crohn's Disease in the Phase 2 AMAG Study

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39093640

BACKGROUND: Fatigue is a burdensome, under-recognized, multidimensional symptom experienced by patients with Crohn's disease (CD). We evaluated the impact of mirikizumab on fatigue and the association between changes in select patient-reported outcomes and clinical measures with changes in fatigue from baseline to week 104 (W104). METHODS: Patients (N = 191) …

Glucagon-like peptide-1 receptor agonists and capsule endoscopy in patients with diabetes: a matched cohort study

Publication Year: 2025 Source: Gastrointest Endosc PMID: 39094916

No Abstract

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