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Treatment Strategies for Chronic Pancreatitis (CP)
Publication Year: 2025 Source: Pharmaceuticals (Basel) PMID: 40143090
Chronic pancreatitis (CP) and autoimmune pancreatitis (AIP) are diseases with overlapping features, both requiring complex management strategies. CP is characterized by pancreatic exocrine insufficiency (PEI) and pain, with treatment focused on symptom relief through pancreatic enzyme replacement therapy (PERT), pain control, and lifestyle and nutritional changes. However, the standard therapy …
Mapping the Evolution of IBD Treatment: A Bibliometric Study on Biologics and Small Molecules
Publication Year: 2025 Source: Pharmaceuticals (Basel) PMID: 40143091 DOI: 10.3390/ph18030312
Objectives: This bibliometric analysis investigates recent research trends in biologics and small molecules for treating inflammatory bowel disease (IBD) based on literature from the past decade. Methods: This cross-sectional study involved analyzing data retrieved from the Web of Science Core Collection (WoSCC) database to examine the evolution and thematic trends …
Ulcerative colitis and bullous pemphigoid: Direct association or a medication side effect: A case report
Publication Year: 2025 Source: World J Clin Cases PMID: 40144487
BACKGROUND: Bullous pemphigoid (BP) is an autoimmune blistering skin disorder. It is associated with other autoimmune disorders and the use of certain drugs. We describe a case of BP in a patient with ulcerative colitis (UC) treated with mesalamine. CASE SUMMARY: A 38-year-old male patient with UC and a history …
Authors' comment on: effectiveness and safety of oral vancomycin for the treatment of inflammatory bowel disease associated with primary sclerosing cholangitis: a systematic review and pooled analysis
Publication Year: 2025 Source: Therap Adv Gastroenterol PMID: 40144790
No Abstract
Trend analysis and cross-national inequity analysis of immune-mediated inflammatory diseases in children and adolescents aged 10-24 from 1990 to 2021
Publication Year: 2025 Source: World Allergy Organ J PMID: 40144860 DOI: 10.1016/j.waojou.2025.101033
INTRODUCTION: Immune-mediated inflammatory diseases (IMIDs) are chronic inflammatory diseases caused by immune system dysregulation, affecting multiple systems and organs. Children and adolescents aged 10-24 are among the high-risk groups, and the global burden is substantial. METHODS: Using the latest data from global burden of disease (GBD) 2021, we employed Joinpoint …
Case Report: Hemolytic anemia secondary to infliximab treatment in a patient with ulcerative colitis
Publication Year: 2025 Source: Front Med (Lausanne) PMID: 40144881 DOI: 10.3389/fmed.2025.1548321
Infliximab, a monoclonal antibody targeting tumor necrosis factor-alpha (TNF-alpha), is widely used in treating inflammatory bowel diseases (IBD), including ulcerative colitis (UC). While generally well-tolerated, infliximab is associated with rare but significant adverse effects, including autoimmune hemolytic anemia (AIHA). This report describes the case of a 54-year-old male diagnosed with …
Sclerosing encapsulating peritonitis in advanced liver cirrhosis presenting with acute small bowel obstruction: a case report and literature review
Publication Year: 2025 Source: J Surg Case Rep PMID: 40145007
Sclerosing encapsulating peritonitis (SEP) is an inflammatory condition characterized by the encasement of the small bowel in a dense fibro-collagenous membrane resulting in acute bowel obstruction. In the context of liver disease, SEP is exceptionally rare, with only eight known cases to date. We describe the case of a 52-year-old …
Imaging the enteric nervous system
Publication Year: 2025 Source: Front Neuroanat PMID: 40145027
The enteric nervous system (ENS) has garnered increasing scientific interest due to its pivotal role in digestive processes and its involvement in various gastrointestinal and central nervous system (CNS) disorders, including Crohn's disease, Parkinson's disease, and autism. Despite its significance, the ENS remains relatively underexplored by neurobiologists, primarily because its …
Caffeic Acid Protects Against Ulcerative Colitis via Inhibiting Mitochondrial Apoptosis and Immune Overactivation in Drosophila
Publication Year: 2025 Source: Drug Des Devel Ther PMID: 40145123
BACKGROUND: Ulcerative colitis (UC) is a chronic intestinal inflammation that is prone to relapse and is difficult to fully recover; therefore, there is a need for safer alternative treatments. Caffeic acid (CA) is a natural polyphenolic compound that has antioxidant and anti-inflammatory properties. However, the beneficial effects and mechanisms of …
CASTOMized project: a new comprehensive collaborative approach between case manager and stoma care nurse
Publication Year: 2025 Source: Br J Nurs PMID: 40145520
BACKGROUND: The use of the Enhanced Recovery After Surgery (ERAS) care pathway is becoming more widespread in surgical specialties. However, the presence of an ostomy, and the patient's need to adapt quickly to living with a stoma, is described as the Achilles' heel of the ERAS pathways in colorectal surgery. …
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