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Endoscopic Techniques for Colorectal Neoplasia Surveillance in Inflammatory Bowel Disease: A Systematic Review and Network Meta-Analysis
Publication Year: 2025 Source: United European Gastroenterol J PMID: 40145876 DOI: 10.1002/ueg2.70017
BACKGROUND AND AIMS: Dye-based chromoendoscopy (DCE) has been the preferred method for colonoscopy surveillance in patients with inflammatory bowel disease (IBD). However, with advances in endoscopy, virtual chromoendoscopy (VCE) techniques have emerged. This network meta-analysis evaluates the effectiveness of different endoscopy techniques for IBD patient surveillance. METHODS: Sixteen randomized controlled …
Patients With Inflammatory Bowel Disease Are at Increased Risk of Respiratory Syncytial Virus Infections After Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Propensity-Matched Cohort Analysis
Publication Year: 2025 Source: Clin Transl Gastroenterol PMID: 40145951 DOI: 10.14309/ctg.0000000000000840
INTRODUCTION: Patients with inflammatory bowel disease (IBD) are at an increased risk of infections. Before the COVID-19 pandemic, respiratory syncytial virus (RSV) followed predictable seasonal patterns, which have been recently disrupted. This study aimed to investigate whether severe acute respiratory syndrome (SARS) coronavirus 2 (CoV-2) infection is associated with an …
Role of computed tomography in imaging of endometriosis
Publication Year: 2025 Source: Abdom Radiol (NY) PMID: 40146309
Endometriosis is a chronic systemic disease characterized by the presence of endometrium-like glands and/or stroma outside the uterus, usually with an associated inflammatory process. It affects around 5-10% of women worldwide, with chronic pelvic pain and infertility being the predominant symptoms. Although suspected clinically, transvaginal ultrasound (TVUS) and magnetic resonance …
Management of Atherosclerotic Cardiovascular Risk in Inflammatory Bowel Disease: Current Perspectives
Publication Year: 2025 Source: Adv Ther PMID: 40146370 DOI: 10.1007/s12325-025-03154-2
Inflammatory bowel disease (IBD) is a complex condition characterized by inflammation of the gastrointestinal system, encompassing Crohn's disease and ulcerative colitis. Patients diagnosed with IBD have an increased risk of atherosclerotic cardiovascular disease. This heightened risk can be attributed to a combination of mechanisms, including traditional risk factors, chronic inflammation, …
Stercoral Colitis: Review of Imaging Features and Complications
Publication Year: 2025 Source: Radiographics PMID: 40146627
Stercoral colitis is an inflammatory reaction secondary to fecal impaction and almost always occurs in the setting of chronic constipation. Luminal distention caused by dense and dehydrated stool compresses the vascular supply of the distal colon, resulting in bowel ischemia and ulceration. Stercoral colitis primarily affects elderly patients, but it …
Ileo-Cecal Lipomatosis Mimicking Acute Appendicitis Complicated with Appendicular Abscess: A Case Report
Publication Year: 2025 Source: Am J Case Rep PMID: 40146673
BACKGROUND Ileo-cecal lipomatosis is a rare, benign condition characterized by diffuse submucosal adipose tissue infiltration in the intestinal wall. While usually asymptomatic, it occasionally presents with complications such as bowel obstruction, perforation, or mimicry of acute appendicitis, often leading to diagnostic challenges. CASE REPORT A 29-year-old obese woman presented to …
Why and when are activity scores and advanced ultrasound techniques needed in inflammatory bowel disease (IBD)?
Publication Year: 2025 Source: Med Ultrason PMID: 40146980 DOI: 10.11152/mu-4500
In addition to avoidance of radiation exposure, the main advantages of ultrasound diagnostics in inflammatory bowel disease (IBD) patients are its' immediate availability, also as a component of the physical examination (extended point of care), its' repeatability and its' high patient comfort. The fact that the examination is carried out …
CGA protects against experimental colitis by modulating host purine metabolism through the gut microbiota
Publication Year: 2025 Source: Int Immunopharmacol PMID: 40147263 DOI: 10.1016/j.intimp.2025.114547
OBJECTIVE: Alterations in the gut microbiota may contribute to the development of inflammatory bowel disease (IBD). Chlorogenic acid (CGA), a product of the esterification of caffeic acid and quinic acid, is one of the most abundant polyphenols in the human diet and has potential beneficial effects on gut function. However, …
Active Inflammatory Bowel Disease on Intestinal Ultrasound During Pregnancy Is Associated With an Increased Risk of Adverse Pregnancy and Neonatal Outcomes Independent of Clinical and Biochemical Disease Activity
Publication Year: 2025 Source: Gastroenterology PMID: 40147617 DOI: 10.1053/j.gastro.2025.03.016
BACKGROUND AND AIMS: Clinically active inflammatory bowel disease (IBD) is associated with an increased risk of adverse pregnancy outcomes. However, the validity of clinical scores to assess antenatal disease activity is questionable. We aimed to assess whether active disease defined by intestinal ultrasound (IUS) may predict adverse pregnancy outcomes. METHODS: …
Flavonoids and their role in oxidative stress, inflammation, and human diseases
Publication Year: 2025 Source: Chem Biol Interact PMID: 40147618
Oxidative stress and chronic inflammation are important drivers in the pathogenesis and progression of many chronic diseases, such as cancers of the breast, kidney, lung, and others, autoimmune diseases (rheumatoid arthritis), cardiovascular diseases (hypertension, atherosclerosis, arrhythmia), neurodegenerative diseases (Alzheimer's disease, Parkinson's disease, Huntington's disease), mental disorders (depression, schizophrenia, bipolar disorder), …
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