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Bacterial dysbiosis in newly diagnosed treatment naïve pediatric ulcerative colitis in Saudi Arabia
Publication Year: 2025 Source: Saudi J Gastroenterol PMID: 38708883
No Abstract
Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder
Publication Year: 2025 Source: medRxiv PMID: 38712091
Obsessive-compulsive disorder (OCD) affects ~1% of children and adults and is partly caused by genetic factors. We conducted a genome-wide association study (GWAS) meta-analysis combining 53,660 OCD cases and 2,044,417 controls and identified 30 independent genome-wide significant loci. Gene-based approaches identified 249 potential effector genes for OCD, with 25 of …
Cardiovascular disease: extraintestinal manifestation of inflammatory bowel disease
Publication Year: 2025 Source: Intest Res PMID: 38712363 DOI: 10.5217/ir.2023.00104
Inflammatory bowel disease (IBD) is a spectrum of diseases characterized by the interplay of the aberrant immune system, genetic factors, environmental factors, and intestinal microbiota, resulting in relapsing inflammation of the gastrointestinal tract. Underlying pro-inflammatory state and immune dysregulation act as a catalyst for increasing the likelihood of developing extraintestinal …
Pediatric Participation in Biobanking Related to Inflammatory Bowel Diseases
Publication Year: 2025 Source: Clin Pediatr (Phila) PMID: 38767312
No Abstract
Predictors of Complicated Disease Course in Children and Adults With Ulcerative Colitis: A Nationwide Study From the epi-IIRN
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 38768390
BACKGROUND: Data on predictors of complicated ulcerative colitis (UC) course from unselected populations cohorts are scarce. We aimed to utilize a nationwide cohort to explore predictors at diagnosis of disease course in children and adults with UC. METHODS: Data of patients diagnosed with UC since 2005 were retrieved from the …
Safety of Immunosuppression in a Prospective Cohort of Inflammatory Bowel Disease Patients With a HIstoRy of CancEr: SAPPHIRE Registry
Publication Year: 2025 Source: Clin Gastroenterol Hepatol PMID: 38768673 DOI: 10.1016/j.cgh.2024.05.006
BACKGROUND & AIMS: In patients with inflammatory bowel disease (IBD) and a history of cancer, retrospective studies have suggested that exposure to immunosuppressive agents does not increase the risk of incident (recurrent or new) cancer compared with unexposed patients. Safety of Immunosuppression in a Prospective Cohort of Inflammatory Bowel Disease …
Jejunal strongyloidiasis mimicking crohn's colitis: A diagnostic dilemma!
Publication Year: 2025 Source: Indian J Pathol Microbiol PMID: 38769818
No Abstract
Sarcoidosis and ulcerative colitis: overlap or coexistence
Publication Year: 2025 Source: Rev Esp Enferm Dig PMID: 38775409
We show an unusual case of ulcerative colitis and sarcoidosis. This case has detailed images of skin lesions, biopsies and PET-CT results. There is limited evidence regarding the association of inflammatory bowel disease and other granulomatous diseases, especially sarcoidosis.
Predictive Factors of Inactive Patient Participation in an Inflammatory Bowel Disease Learning Health System: A Longitudinal Cohort Study
Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 38775837
No Abstract
A scoping review of the qualitative literature reporting experiences of living with a stoma for inflammatory bowel disease
Publication Year: 2025 Source: J Adv Nurs PMID: 38780277 DOI: 10.1111/jan.16254
AIMS: Surgical treatment for inflammatory bowel disease (IBD) potentially includes stoma formation. Although positive clinical outcomes are widely reported, patients' responses to stoma surgery, including coming to terms with and adjusting to the stoma, vary widely. This scoping review charts the qualitative literature addressing the question: What is known about …
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