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Evaluation of intestinal biopsy tissue preservation methods to facilitate large-scale mucosal microbiota research

Publication Year: 2025 Source: EBioMedicine PMID: 39742562

No Abstract

Development and validation of the Crohn's disease-intestinal failure-wean (CDIF-Wean) Score to predict outcomes of intestinal rehabilitation

Publication Year: 2025 Source: Clin Nutr PMID: 39742590

No Abstract

Smoking Experience before Adulthood Is Associated with an Increased Risk of Developing Ulcerative Colitis in Adult Ex-Smokers

Publication Year: 2025 Source: Yonsei Med J PMID: 39742880 DOI: 10.3349/ymj.2023.0612

PURPOSE: Smoking may have a protective role in developing ulcerative colitis (UC) but have the opposite effect on Crohn's disease (CD). This study aimed to determine the risk of developing inflammatory bowel disease (IBD) according to smoking status and onset age of smoking. MATERIALS AND METHODS: We collected data on …

Biological agents as attractive targets for inflammatory bowel disease therapeutics

Publication Year: 2025 Source: Biochim Biophys Acta Mol Basis Dis PMID: 39743022 DOI: 10.1016/j.bbadis.2024.167648

Inflammatory bowel disease (IBD) refers to a group of chronic, recurrent intestinal inflammatory conditions with a complex cause and unclear underlying mechanisms. It includes two main types: Ulcerative colitis (UC) and Crohn's disease (CD). The conventional treatment of IBD mainly includes 5-aminosalicylates, glucocorticoids, and immunosuppressive drugs, which have their limitations. …

Active components unveiling and pharmacodynamic research on Valeriana jatamansi jones for ameliorating ulcerative colitis based on pharmacokinetics and network pharmacology

Publication Year: 2025 Source: J Ethnopharmacol PMID: 39743185

No Abstract

Treatment Persistence Among Anti-Tumor Necrosis Factor-experienced Patients With Ulcerative Colitis Switching to a Biologic With a Different Mode of Action or Cycling to Another Anti-Tumor Necrosis Factor Agent

Publication Year: 2025 Source: Clin Ther PMID: 39743427

No Abstract

Ozanimod and Vedolizumab as First-Line Advanced Therapies in Ulcerative Colitis

Publication Year: 2025 Source: Inflamm Bowel Dis PMID: 39743498

No Abstract

The Genetic Causal Effect of Autoimmune Diseases on pan-Cancers: Evidence from Mendelian Randomization

Publication Year: 2025 Source: J Cancer PMID: 39744497

Background: Whether autoimmune diseases caused any effects on the risk of cancers remained yet clarified. This study aimed to investigate the causal effect of autoimmune diseases on pan-cancers through mendelian randomization (MR) analysis. Method: The GWAS summary datasets of 10 autoimmune diseases were derived from the IEU or UK biobank …

Ileal Predominance in Crohn's Disease Is Associated With Increased Intestinal Surgery and Biological Therapy Use, With Lower Treatment Persistence

Publication Year: 2025 Source: Am J Gastroenterol PMID: 39745305

No Abstract

Identification and characterization of Faecalibacterium prophages rich in diversity-generating retroelements

Publication Year: 2025 Source: Microbiol Spectr PMID: 39745426

No Abstract

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